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The study revealed the mechanism by which APOE4 regulates Alzheimer's disease
Time of Update: 2021-01-05
September 3rd, Professor Jia Jianping of Xuanwu Hospital, Capital Medical University, published a study online in the journal Alzheimer's disease and dementia on the distribution and action patterns of the Alzheimer's risk gene APOE 4.
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The new fusion protein therapy is expected to treat clotting disorders
Time of Update: 2021-01-05
researchers have developed an experimental fusion protein called BIVV001, which has not been shown to stop haemophilia patients from bleeding in a large-scale clinical trial, but it can prolong the clotting factor, much to the excitement of some researchers.
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FMD |。 How long can immunity last after a new coronavirus infection?
Time of Update: 2021-01-05
In order to determine whether antibodies can exist in the human body for a long time after the new coronavirus infection, the National Translational Medical Center of Ruijin Hospital, Shanghai Hematology Research Institute, National Key Laboratory of Medical Genomics, Shanghai Public Health Clinical Center and China Food and Drug Inspection Research Institute have carried out long-term monitoring of new crown infection.
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Studies have found that a protein secreted by the liver lowers blood sugar
Time of Update: 2021-01-05
australia and other countries have found that a protein naturally secreted by the liver can lower blood sugar levels in mice with diabetes, hoping to develop new drugs to treat type 2 diabetes in the future.
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The study found a new disease-caused gene for weak malformation sperm disease
Time of Update: 2021-01-05
recent years, The team of Cao Yunxia, president and professor of Anhui Medical University, has been working on the study of weak malformation sperm disease and has identified a number of disease-causing genes that cause multiple morphological abnormalities (MMAF) of sperm whiplash.
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The mechanism of immune T cell "dryness" to promote anti-tumor effect is revealed
Time of Update: 2021-01-05
The joint study found that cGAS-STING is important for dry CD8T cells in patients with gynaecological tumor ovarian, cervical and endometrial cancers.
STING excitants can promote the differentiation of outer blood T-cells in healthy populations and cancer patients, and can significantly improve the efficacy of CAR-T immunotherapy for solid tumors.
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A new type of primary myoprotein-like subject kinase inhibitor has been developed
Time of Update: 2021-01-05
recently, Liu Qingsong and Liu Jing Pharmaceuticals, researchers at the Institute of Health and Medical Technology of the Hefei Institute of Physical Sciences in China, developed a new type of primary muscle -subject kinase (TRK) small molecule inhibitor IHMT-TRK-284.
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Urban air pollution may be added to the condition of re-coronary pneumonia
Time of Update: 2021-01-05
In a recent study published in the journal of Cell Press, researchers at Emory University in the United States found that long-term exposure to urban air pollution may make COVID-19 more deadly.
" long-term exposure to urban air pollution, particularly no pollution, may increase the sensitivity of severe COVID-19 deaths.
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BMC focuses on post-epidemic era . . Go ahead and talk about public health and epidemiology
Time of Update: 2021-01-05
。 Citation Impact 2.567 - 2-year IF 3.275 - 5-year IF 1.342 - SNIP 1.382 - SJR is an open access, peer-reviewed journal that considers articles on the epidemiology of disease and the understanding of all aspects of public health.
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The association between cooking oil and diabetes risk
Time of Update: 2021-01-05
At the same time, the study also analyzed the relationship between dietary n-6 fatty acids and intestinal bacteria diversity and diabetes: Dietary n-6 polyunsaturated fatty acids are likely to reduce bacterial diversity and increase the risk of diabetes, the results confirm the association between blood metabolites γ-flax acid and bacteria and diabetes.
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Studies have confirmed the effectiveness of ctDNA methylation screening techniques
Time of Update: 2021-01-05
Fudan University Taizhou Institute of Health Sciences and human esophagic group research institute researcher Chen Xingdong team found that for colorectal cancer, esophageal cancer, liver cancer, lung cancer and stomach cancer, such as 5 common malignancies, before reaching the existing standard of clinical diagnosis, even before the patient has conscious symptoms, early cancer signal - trace tumor methylation is present in the blood circulation, and can be non-invasing detection, time can be 4 years earlier than conventional diagnosis.
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Add a "safety lock" to gene and cell therapy
Time of Update: 2021-01-05
on August 8th, Ye Haifeng, a researcher at the School of Life Sciences and the Center for Medical Synthetic Biology research at East China Normal University, published their latest research results online in Science Advances, using the design ideas of synthetic biology to develop a safe and efficient gene control switch for the regulation of the natural green small molecule, clinically approved drug sodium aweiteate.
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Scientists advance research and practice on "healthy" childbirth
Time of Update: 2021-01-05
As World Health Organization mentioned in its 2018 "Birth Care for a Positive Delivery Experience", women's experience of childbirth care is a global public health issue.
, Patrick Moran of the University of Dublin in Ireland and colleagues studied the long-term effects of reducing caesarean section rates and increasing vaginal delivery (VBAC) rates.
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Scientists build better antibiotics
Time of Update: 2021-01-05
Ian Seiple and colleagues at the University of California, San Francisco, reported a method of synthesized streptococcus A that avoids resistance caused by Vatase.
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What used to help you withstand famine now makes you stock up on fat
Time of Update: 2021-01-05
Wang Lifeng, the first author of the paper, told China Science that in his previous work, he and his co-author Anders Naar, a former Harvard Medical School professor, screened several small RNAs associated with metabolic diseases such as obesity and diabetes.
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Models predict which children are at risk of obesity
Time of Update: 2021-01-05
researchers at the Centers for Disease Control and Control in Yantai City collected data on 45,540 boys and 43,440 girls aged 6-11 in the city from 2013 to 2018 and divided them into four groups by BMI: underweight (2,940), normal weight (48,924), overweight (15,278), and obesity (21,838).
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Scientists have confirmed that sleeping 6-7 hours a night can prevent dementia
Time of Update: 2021-01-05
For the first time, researchers have confirmed the U-shaped relationship between nighttime sleep time and Alzheimer's pathology in middle-aged and elderly people: sleep deprivation or excess can promote abnormal deposition of amyloid protein in the body, which is a common pathogen and a key factor in the formation and development of Alzheimer's disease, and one of the core pathological characteristics of Alzheimer's disease.
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The general nutritional intake of lactating women in China is not balanced
Time of Update: 2021-01-05
However, a recent Danon Newdishia in China participated in a sample size of more than 5000 people "maternal and child population dietary nutrition survey analysis study" (referred to as maternal and child nutrition survey) shows that China's lactating women generally nutritional imbalance, such as more than 90% of the respondents vitamin A intake did not reach the average demand.
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Regulating the core rhythm protein may help to delay disease prevention
Time of Update: 2021-01-05
Qu Jing, co-author of this paper and a researcher at the Institute of Zoology of the Chinese Academy of Sciences, said that injection of THEC zovirus expression vector through joint cavity can reduce the proportion of senescing cells, inhibit inflammatory reactions and stimulate cartilage regeneration, relieve age-related bone and joint degeneration, and improve the motor ability of elderly mice.
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The flux vaccination tool recreates the history of the virus
Time of Update: 2021-01-05
, published July 20 in Genomic Biology, showed that strains of the virus used in the U.S. Civil War vaccine had been identified and their genomes reconstructed.
Duggan and colleagues collected genetic material from U.S. Civil War-era vaccination tools to identify the strains used to vaccinate against the flux.