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Phase 3 clinical results of recombinant protein new crown vaccine candidate are positive
Time of Update: 2021-06-21
On June 14, 2021, Novavax announced that its recombinant protein-based nanoparticle new crown vaccine candidate NVX-CoV2373 has reached the primary endpoint in a pivotal phase 3 clinical trial, with an overall protective efficacy of 90.
com/pr/novavax -covid-19-vaccine-19-demonstrates-90-overall-efficacy-and-100-protection-against-moderate-and-severe-disease-in-prevent-19-phase-3-trial
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Alzheimer's vaccine shows good momentum
Time of Update: 2021-06-21
The researchers said that although patients tolerate AADvac1 well and can produce an immune response to tau protein, the vaccine cannot produce statistically significant cognitive benefits.
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New research details arena virus replication regulation mechanism
Time of Update: 2021-06-21
In order to systematically study the replication mechanism of arenavirus, Shi Yi's team analyzed the fine three-dimensional structure of two representative viruses in the Old World and New World arenavirus groups-Lassa virus and Maqiubo virus polymerase .
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The new crown pneumonia vaccine is safe and effective for cancer patients
Time of Update: 2021-06-21
Cancer Cell In a study of 200 confirmed cancer patients, researchers at Montefiore Health Center and Einstein College of Medicine found that after the vaccination was completed, 94% of patients showed seroconversion as a whole.
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The director of the National Analysis and Testing Center and the head of the local association jointly researched instrument innovation
Time of Update: 2021-06-17
Professor Zaipal Abulizi, Vice Chairman of China Analysis and Testing Association, Vice President of Minzu University of ChinaTopic of the report: Research progress of biomedicine based on modern analytical technology Professor Zaipal Ablizi introduced cryo-electron microscopy, near-infrared spectroscopy, mass spectrometry including capillary isoelectric focusing directly coupled to high-resolution mass spectrometry and other applications and research progress in different fields .
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How healthy are you
Time of Update: 2021-06-16
The research team also measured the participants’ maximum oxygen uptake before and after a 20-week exercise program, an indicator of cardiometabolic health .
With the deepening of the research, the author stated that the blood's oxygen-carrying protein can be used as a biomarker of a person's health and future health risks .
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S protein is easy to mutate, can N protein take up the important task of new crown antibody drugs
Time of Update: 2021-06-16
It is precisely because of the increased drug resistance of the virus and the increased risk of single-agent treatment failure caused by the mutation that the US Food and Drug Administration revoked the emergency use authorization of Eli Lilly's new crown antibody drug LY-CoV555 in April this year .
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Tetanus monoclonal antibody is expected to become mainstream drugs
Time of Update: 2021-06-16
In the study of tetanus monoclonal antibody, the researchers obtained the co-crystal structure of TT0067Fab and the C segment of recombinant tetanus toxin, and found that TT0067Fab can replace the GD1a receptor of ganglioside and bind to the C segment of tetanus toxin, thus acting Effectively neutralize the effects of toxins .
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Is the risk of stroke destined?
Time of Update: 2021-06-16
Based on this, Lu Xiangfeng and the team of Gu Dongfeng, an academician of the Chinese Academy of Sciences, established the first Chinese stroke polygenic genetic risk scoring model after years of research, and combined with traditional risk factor screening, it helps to accurately predict and analyze the risk of stroke.
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Rewriting the genetic code of bacteria to open the "gate" to new drug research
Time of Update: 2021-06-16
Jason Chin, a synthetic biologist at the Molecular Biology Laboratory of the American Medical Research Council, said that although this method has become more complicated, under normal circumstances, each protein can still only insert one amino acid .
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Research found a new mechanism of foot-and-mouth disease virus L protein antagonizing host immunity
Time of Update: 2021-06-16
The study found that FMDV L protein inhibits the activation of the OAS/RNase L signaling pathway by interacting with the N-terminal domain of RNase L, revealing a new mechanism by which FMDV L protein antagonizes the host’s innate immunity.
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Alcohol consumption is linked to a lower chance of pregnancy
Time of Update: 2021-06-16
Studies have shown that during the luteal phase, which is the last two weeks of the menstrual cycle, before bleeding begins and during implantation, both heavy and moderate drinking are significantly associated with a lower probability of pregnancy .
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Chinese scholars innovate the treatment model of nasopharyngeal carcinoma
Time of Update: 2021-06-16
Unlike traditional chemotherapy that uses the maximum tolerated dose to treat tumors, capecitabine can be administered for a long time by low-dose, long-term oral administration of "beating" Maintained at a relatively low blood drug concentration, which can reduce toxic side effects while continuing to fight tumors, and is especially suitable for maintenance treatment of patients after radiotherapy and chemotherapy .
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From "no one cares" to "people in the world", how mRNA drugs become the new darlings
Time of Update: 2021-06-16
In the same year, Translate Bio and Sanofi established a cooperative relationship to use breakthrough mRNA platform technology to develop mRNA vaccines against a variety of infectious diseases; in March 2020, both parties The agreement reached in 2018 will continue to cooperate in the development of an mRNA vaccine for the new coronavirus pneumonia .
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Another inactivated new crown vaccine in my country is on the market, using 2 doses throughout the course of vaccination
Time of Update: 2021-06-16
(Sina Pharmaceutical News)On June 9th, the first batch of Covey's new coronavirus inactivated vaccines independently developed by the Institute of Medical Biology of the Chinese Academy of Medical Sciences (hereinafter referred to as the Institute of Biology of the Chinese Academy of Medical Sciences) was launched for emergency domestic use .
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High-fat diet induces antibiotic tolerance
Time of Update: 2021-06-16
The first author and co-corresponding author of the paper, Professor Liu Yuan of Yangzhou University, said in an interview with "China Science Daily" that antibiotic resistance can be determined by genomic analysis and minimum inhibitory concentration (MIC) test: antibiotic resistant bacteria Not only has the corresponding drug resistance gene, but also the MIC will increase significantly .
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Bayer promotes two first cell and gene therapies to treat Parkinson's disease
Time of Update: 2021-06-16
Bayer Group announced on June 8 that its wholly-owned clinical trial phase biopharmaceutical company BlueRock (BlueRock Therapeutics) has successfully completed the administration of a Parkinson’s disease patient in an open-label phase I clinical study.
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Wake up 1 hour early to reduce the risk of depression by 23%
Time of Update: 2021-06-16
Researchers from the University of Colorado at Boulder, Massachusetts Institute of Technology, and Harvard University studied 840,000 people, providing strong evidence that sleep patterns (a person’s tendency to sleep at a specific time) affect the risk of depression .
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No fish to eat will cause malnutrition
Time of Update: 2021-06-16
Shahid Naeem, co-author of the study and director of Columbia University’s Center for Sustainable Research on the Earth’s Environment, said: “Different types of plants and animals contain different nutrients, so biodiversity is the key to adequate human nutrition .
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Novartis announces overall survival data for MET inhibitors
Time of Update: 2021-06-16
(WuXi AppTec) Recently, at the American Society of Clinical Oncology in 2021, Novartis announced the latest phase 2 clinical trial data of the oral highly selective small molecule MET inhibitor Tabrecta in the treatment of adult patients with metastatic non-small cell lung cancer .
