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An Alzheimer's disease vaccine shows safety and immune response
Time of Update: 2021-06-28
(China News Network) Springer Nature's professional academic journal "Nature-Aging" recently published a medical research paper saying that researchers conducted Phase 2 clinical trial results of a vaccine developed for Alzheimer's disease (AD) commonly known as Alzheimer's disease Shows that this vaccine called AADvac1 is safe and can induce immune responses in patients with mild Alzheimer's disease .
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Cell sub-news reveals a new mechanism of hair regrowth potential
Time of Update: 2021-06-21
Recently, researchers from the Chinese Academy of Sciences published an online article entitled miR-24 controls the regenerative competence of hair follicle progenitors by targeting Plk3 in the internationally renowned journal Cell Reports, revealing a miRNA-mediated skin follicle (HF) The regeneration mechanism of precursor cells provides important clues for the treatment of hair loss .
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The latest international research: an Alzheimer's disease vaccine shows safety and immune response
Time of Update: 2021-06-21
The authors of the paper generally concluded that although patients have a good tolerance to AADvac1 and can produce an immune response to tau protein, the vaccine cannot produce statistically significant cognitive benefits.
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A synthetic probiotic can treat colorectal cancer
Time of Update: 2021-06-21
The author’s work in this study showed that effective and stable synthetic probiotics composed of Pseudomonas pentosaceus and P8 therapeutic protein can reduce colorectal cancer and help rejuvenate bacteria, and cell-based design of biological drugs Effectiveness and feasibility in treating colorectal cancer and improving the damaged microflora .
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Human Virome Heterogeneity Assessment Report Published
Time of Update: 2021-06-16
(Technology Daily)Recently, it was learned from the Computational Biology and Medical Ecology Group of the Kunming Institute of Zoology, Chinese Academy of Sciences that the research group recently published a human virion heterogeneity assessment report in the international journal "Journal of Computational and Structural Biotechnology" to deepen the understanding of the human virion group.
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No medicine, no surgery, FDA approves new technology to relieve pain from osteoarthritis
Time of Update: 2021-06-16
Retrieved June 9, 2021, from https:// -stimulation-system-to-treat-osteoarthritic-kneeOn June 9, 2021, CyMedica Orthopedics announced that the US FDA has approved a regulatory application for its IntelliHab system to relieve knee osteoarthritis (knee osteoarthritis) pain .
Retrieved June 9, 2021, from https:// cymedica-orthopedics-announces-fda-clearance-for-intellihab-a-novel-drug-free-non-invasive-modality-for-treatment-of-knee-osteoarthritis-pain-301308495.
Retrieved June 9, 2021, from https:// cymedica-orthopedics-announces-fda-clearance-for-intellihab-a-novel-drug-free-non-invasive-modality-for-treatment-of-knee-osteoarthritis-pain-301308495.
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Xinrui α-Radiation Cancer Therapy Receives FDA Breakthrough Medical Device Certification
Time of Update: 2021-06-16
Recently, Alpha Tau Medical announced that its alpha-radiation cancer therapy Alpha DaRT has obtained the Breakthrough Device Designation granted by the US FDA, which is suitable for the treatment of skin and oral scaly without standard treatments.
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Science: Demystifying the mechanism of obesity genes affecting the brain
Time of Update: 2021-06-16
The researchers used a mouse model that lacked obesity-related regions in the FTO gene to observe the expression of IRX3 and IRX5 genes in different tissues of mice .
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Seeing through the "trick" of cancer cells brings new hope to patients with colorectal cancer
Time of Update: 2021-06-16
Therefore, in order to explore the interaction between cancer-promoting mutant cells and normal neighboring cells, researchers at the Cambridge Stem Cell Institute developed a microscopy technique that uses multicolor labeling technology to track the trajectories of single mutant genes Kras and Pik3ca , Studies have found that mutated cancer stem cells can secrete specific cytokines and inhibit the activity of surrounding healthy intestinal stem cells .
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China's self-developed ADC new drug approved for the market for the treatment of gastric cancer
Time of Update: 2021-06-16
By tumor Peking University Hospital of registered clinical trials Wei Dixi trastuzumab Shen Lin, vice president of Tianjin Cancer Hospital, vice president and a co-lead Pakistan to carry out the treatment of gastric cancer showed for 127 had received second-line chemotherapy in HER2 For patients with moderately high expression of advanced or metastatic gastric cancer, the objective remission rate reached 24.
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The research and development of antibody conjugate drugs continues to heat up
Time of Update: 2021-06-11
ADC market heats up ADC is formed by coupling a monoclonal antibody targeting a specific antigen and a small molecule cytotoxic drug through a linker.
ADC market heats up ADC is formed by coupling a monoclonal antibody targeting a specific antigen and a small molecule cytotoxic drug through a linker.
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New drug for treatment of essential hypertension approved in China to lower blood pressure while reducing the risk of cardiovascular events
Time of Update: 2021-06-11
A number of studies have also shown that, regardless of the level of blood pressure in hypertensive patients, whether they are associated with risk factors or heart and kidney damage, sacubitril and valsartan show a general antihypertensive effect.
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New research finds: oral bacteria may activate oncogenes
Time of Update: 2021-06-10
In the future, researchers will focus on the prevalence of Candida albicans and Staphylococcus aureus biofilms in the dentures and oral cavity of patients with head and neck cancer.
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Nature Sub-Journal: Single-base editor helps treat liver disease
Time of Update: 2021-06-10
The use of lipid nanoparticles to achieve the delivery of ABE-encoding genes and a single guide RNA targeting PCSK9 (negative regulator of LDL), which can achieve up to 67% base editing (an average of 61%) level in mice, and in rhesus monkeys Editing efficiency of up to 34% (26% on average) can also be achieved.
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Innovative domestic drug approved for treatment of advanced squamous non-small cell lung cancer
Time of Update: 2021-06-10
It is reported that in Daboshu's layout for squamous non-small cell lung cancer, in addition to the first-line treatment approved this time, the key phase III clinical study of the second-line treatment also achieved positive results.
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New method to correct disease-causing gene mutations makes gene therapy safer
Time of Update: 2021-06-08
A research team led by Professor Feng Guoping, a professor at the McGovern Brain Institute at the Massachusetts Institute of Technology (MIT) and an academician of the American Academy of Arts and Sciences, unexpectedly discovered that a molecule can Greatly increase the efficiency of CRISPR gene editing tools, and on this basis, developed a new gene editing technology that can be used to study and change disease-causing gene mutations.
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The first Shandong pharmaceutical company that has been evaluated for anti-tumor injection is about to be approved
Time of Update: 2021-06-04
Source: Company announcement, Minet database Medical Network News, June 2 Recently, Shandong New Times Pharmaceutical's application for the imitation of Epirubicin Hydrochloride Injection Type 4 has entered the administrative examination and approval stage.
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Reactivate "paralyzed" immune system to attack deadly brain cancer
Time of Update: 2021-06-04
The study found that it was the cancer-promoting metabolite R-2-HG that interfered with the amino acid metabolism of "cell scavenger" macrophages, and activated the central immune system regulatory molecule aryl hydrocarbon receptor (AHR), thereby causing macrophages to produce Immunosuppressive response.
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Geologists reveal the structure of kidney stones and propose new methods of prevention and treatment
Time of Update: 2021-06-04
Recently, this research team collaborated with researchers from Mayo Clinic to publish a paper in Nature Reviews Urology under the umbrella of Nature, detailing the various stages of the kidney stone deposition process.
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Niacinamide can also regulate retinal function and effectively improve glaucoma
Time of Update: 2021-06-04
In short, the study found that taking nicotinamide can supplement NAD that is gradually depleted with age or IOP, protect retinal ganglion cells, and effectively prevent glaucoma in animal models.
