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[Blood Adv] Results of a Phase I study of carfilzomib in combination with R-ICE regimen in the treatment of R/R DLLBCL
Time of Update: 2023-01-04
Kafilzomib-R-ICE For diffuse large B-cell lymphoma (DLBCL), first-line chemoimmunotherapy cures most patients, but relapsed/refractory (R/R) disease occurs in about 30% of patients with DLBCL. Patient
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The risk of all-cause death is 8.8 times higher than that of the general population! Complications of HSCT should not be underestimated
Time of Update: 2023-01-04
Classification of hematopoietic stem cell transplantation The BMTS cohort studied long-term outcomes in patients who survived ≥ 2 years after Allo-HSCT was performed between January 1, 1974 and December 31, 2014 at the University of Minnesota or the University of Alabama at Birmingham.
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[BLOOD] del(1p32) is a poor prognosis for NDMM, and biallele censoring is ultra-risky
Time of Update: 2023-01-04
of France analyzed the data of 2551 NDMM patients in the French Myeloma Collaboration Group (IFM), confirming the adverse effects of del(1p32) in MM, and the copy number of del(1p32) is also important.
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Preliminary exploration of lenalidomide in combination with obinutuzumab and CHOP in the treatment of treatment-naïve DLBCL
Time of Update: 2023-01-04
hypothesized that lenalidomide and obinutuzumab in combination with CHOP chemotherapy would exhibit high efficacy and tolerable toxicity profile, and conducted a Phase Ib/II single-center clinical trial (NCT02529852) of LO-CHOP for the treatment of patients with newly diagnosed DLBCL, which also included circulating tumor DNA (ctDNA) analysis to measure baseline tumor burden, molecular response, and molecular 。 The findings were recently published in Blood Advance.
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Type O blood wins! The latest research has found that blood type can predict the risk of stroke before the age of 60, and blood type O has the lowest risk!
Time of Update: 2023-01-04
Mitchell said: "Our meta-analysis looked at people's genetic profiles and found an association between blood type and early-onset stroke risk.
Mitchell said: "Our meta-analysis looked at people's genetic profiles and found an association between blood type and early-onset stroke risk.
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Int J Clin Pract: Effects of anaemia on hospital readmissions and death in octogenarians with lower respiratory tract infections: a retrospective cohort study
Time of Update: 2023-01-04
A team of researchers investigated whether anemia is a risk factor for hospital readmissions and death in octogenarians due to LRTI.
A team of researchers investigated whether anemia is a risk factor for hospital readmissions and death in octogenarians due to LRTI.
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A clinical predictive model for first-line imatinib treatment failure in chronic myeloid leukemia
Time of Update: 2023-01-04
Recently, the team of Professor Jiang Qian & Huang Xiaojun of the Institute of Hematology of Peking University published a clinical prediction model on the failure of chronic myeloid leukemia to receive imatinib.
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Professor Zhu Jun: A new generation of anti-CD20 monoclonal antibody brings new choices and hopes to lymphoma patients!
Time of Update: 2023-01-04
As the first monoclonal antibody applied to clinical tumor treatment, its emergence has increased the cure rate and 5-year survival rate of lymphoma patients, especially aggressive B-cell lymphoma patients, by at least 15%~20%, bringing good news to millions of patients around the world.
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Anemia blood diseases, what are the routine test items?
Time of Update: 2023-01-04
If the diet does not pay attention to iron supplementation, it will lead to iron deficiency anemia, which is the most common in China, which can occur both men and women, with an incidence of 40% in infants and young children, 20% in pregnant women and 12% in women during childbirth.
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A condensation specimen that made me break out in a cold sweat
Time of Update: 2023-01-04
PrefaceWith the continuous development of science and technology, the degree of automation of inspection equipment is getting higher and higher, and when processing specimens in large quantities, it i
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Clinical significance and value of the new four tests for thrombosis!!
Time of Update: 2023-01-04
What is a thrombotic disease?Thrombosis is a disease with insidious onset, sudden onset, and high rate of death and disability, which can be found in almost all clinical departments, and its pathological process involves three major systems: vascular endothelium, coagulation and fibrinolysis.
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Urine hCG positive, serum hCG negative, what causes it?
Time of Update: 2023-01-04
Case studyThe patient is a woman of childbearing age, the following abdominal pain is admitted to the hospital, the clinician immediately prescribes the examination items, and the telephone informed our department that the patient requested to be urgent, and after receiving the specimen, the personnel of each position immediately began the experiment, the test results showed: urine pregnancy test (+), after confirming that the report was correct, is it an ectopic pregnancy?
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Thrombocytopenia? Differential diagnosis in three steps!
Time of Update: 2023-01-04
Step two Thrombotic thrombocytopenic purpura/haemolytic uremic syndrome (TTP/HUS) should be considered, as these conditions require special approaches to urgent treatment (e.
Step two Thrombotic thrombocytopenic purpura/haemolytic uremic syndrome (TTP/HUS) should be considered, as these conditions require special approaches to urgent treatment (e.
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Get to know thrombotic thrombocytopenic purpura in five minutes
Time of Update: 2023-01-04
【Clinical manifestations】The clinical manifestations of classic TTP include the five signs of microangiopathic hemolytic anemia, thrombocytopenia, neurological symptoms and signs, renal damage, and fever.
【Clinical manifestations】The clinical manifestations of classic TTP include the five signs of microangiopathic hemolytic anemia, thrombocytopenia, neurological symptoms and signs, renal damage, and fever.
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Have a "feeling" and talk about those things in the inflammatory response
Time of Update: 2023-01-04
Continue to pay attention to the progress of the patient's disease course, severe pneumonia runs through the entire process of the patient's admission to discharge, and the test results are as follows (chronological order from right to left):As can be seen from the table above, the following changes occur as the disease progresses:(1) White blood cells: gradually rise, and neutrophils are mainly elevated.
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Clinical application of serum amyloid A (SAA)!
Time of Update: 2023-01-04
Clinical significance of SAA △ Clinical interpretation of SAA level△ Summary of applicable departments, indications and clinical applications of SAA SAA is widely used in the auxiliary diagnosis of infectious diseases, the risk prediction of coronary heart disease, the dynamic observation of the efficacy and prognosis of tumor patients, the observation of transplant rejection, and the observation of rheumatoid arthritis improvement.
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【Key points】Diagnosis of iron deficiency anemia!
Time of Update: 2023-01-04
Bone marrow iron stainingWith ACD and iron deficiency anemia, transferrin saturation decreases, and ferritin levels are defined as <100 micrograms/L.
In IR iron deficiency anemia, transferrin saturation is low, but serum ferritin levels are normal or low (Figure 1).
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Recognize drug-induced thrombocytopenia
Time of Update: 2023-01-04
summary Drug-induced thrombocytopenia (DITP), which also includes thrombocytopenia caused by beverages, foods and herbal remedies, is an important clinical problem for hematologists.
summary Drug-induced thrombocytopenia (DITP), which also includes thrombocytopenia caused by beverages, foods and herbal remedies, is an important clinical problem for hematologists.
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The world's first! Artificial blood successfully transfused into the body, no adverse reactions, blood type customization!
Time of Update: 2023-01-04
” "Artificial blood" test: addressing the need for rare blood types NHSBT is responsible for blood donation services in England and transplant services across the UK, including managing donation, storage and transplantation of blood, organs, tissues, bone marrow and stem cells, as well as researching new treatments and processes.
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The Phase 3 trial of ICLUSIG® (ponatinib) for the treatment of newly diagnosed Ph+ ALL met the primary endpoint, and no targeted agents have been approved in the US for these patients
Time of Update: 2023-01-04
® Important security information Warnings and precautions Arterial occlusive events (AOE): AOE occurs in both OPTIC and PACE patients, including fatal cases, in patients treated with ICLUSIG.
