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The gut microbiota improves nonalcoholic steatohepatitis aggravated by smoking by degrading nicotine
Time of Update: 2022-10-25
Tobacco use is the leading preventable cause of disease and death globally. China's direct smoking population exceeds 300 million, and the number of people passively exposed to the smoke environment
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It's not just neurons that cause pain, there are another type of cell!
Time of Update: 2022-10-25
In a study published Oct. 7 in Science Advances, the team dubbed the phenomenon a "macrophage-to-neuron-like transition," or MNT, which may explain why some cancer patients are unable to relieve pain by using traditional painkillers, said co-author Patrick Tang, a biochemist at Chinese University in Hong Kong.
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Personalized fingerprinting of sleep brain waves provides powerful new tools for understanding disease
Time of Update: 2022-10-25
In fact, since the mid-30s of the 20th century, people have begun to study sleep EEG by observing brain wave graphics drawn by machines on paper tape.
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Cell Rep: The assembly mechanism of microbial communities in metabolic division of labor
Time of Update: 2022-10-25
The famous economist Adam Smith pointed out in his classic book "The Wealth of Nations" that the division of labor is one of the main ways to increase labor productivity and increase national wealth.
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The ancestors of this fruit are more interesting and complex than imagined
Time of Update: 2022-10-25
An extensive genetic analysis of more than 100 species of wild and cultivated bananas uncovered the tangled history of bananas during domestication, revealing the existence of three previously unknown ancestors who may still be alive.
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PNAS: a new strategy to inhibit the growth of prostate cancer
Time of Update: 2022-10-25
essayA COP1-GATA2 axis suppresses AR signaling and prostate cancer The search for valuable interventions for prostate cancer treatment has guided research in Dr. Yang Feng's lab at Baylor College of Medicine.
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PNAS Cognitive Processing Innovation Theory: In addition to neurons, astrocytes are also involved in memory and behavior
Time of Update: 2022-10-25
"New research paves way for innovative theory of cognitive processing Textbooks we are familiar with generally describe the role of glial cells as follows: (1) providing scaffolding for neuronal growth; (2) Formation of an insulating layer (myelin sheath) around neurons, so that nerve impulses can be transmitted quickly; (3) Deliver nutrients to neurons and remove excessive neurotransmitters between neurons.
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The NIH allocated $4.6 million to better identify lung cancer
Time of Update: 2022-10-25
His goal is to develop and validate innovative biomarkers extracted from nasal swabs, blood, and advanced imaging assays to identify intermediate-risk lung nodules detected through screening or as part of routine clinical care as lung cancer.
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Both drugs reversed a key step in pancreatic cancer in the lab
Time of Update: 2022-10-25
The hidden nature of pancreatic cancer caught the attention of scientists at the University of Florida, who discovered a way to reverse a key cellular process in its development.
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Nucleic Acids Research: Questioning the safety of in vivo gene editing
Time of Update: 2022-10-25
In recent years, a new generation of gene editing tools such as CRISPR-Cas has shown great application prospects in the process of tumor immunotherapy and gene in vivo therapy. The optimization of ge
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PNAS: How the virus attacks a cat's kidneys and then passes it on to humans
Time of Update: 2022-10-25
In a study published this week in the Proceedings of the National Academy of Sciences, virologists at the University of Pittsburgh's Vaccine Research Center reverseengineered an elusive virus linked to chronic kidney disease in cats and described its infection mechanism, outlining its potential to infect humans.
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Wang Yingxiang's team revealed the molecular mechanism of meiosis heterochromatin concentration
Time of Update: 2022-10-25
Wang Yingxiang's team revealed the molecular mechanism of meiosis heterochromatin concentrationMeiosis is a necessary life process for the sexual reproduction of eukaryotes, which through homologous chromosome recombination, free combination of non-homologous chromosomes and two divisions finally form haploid gametes, which ensures the relative stability of genetic material and increases the differences between individuals, so that species can reproduce and evolve.
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Xiao Hua's research group and collaborators of Shanghai Jiaotong University proposed a new strategy for macroproteomics research
Time of Update: 2022-10-25
In order to break through the above bottlenecks, researchers developed a new strategy for preprocessing microbial samples, constructed high-resolution free-flow isoelectric focusing electrophoresis, realized the isolation, enrichment and preparation of complex microorganisms, significantly improved the protein elucidation and identification ability of microbiome by liquid chromatography-mass spectrometry, and established an integrated macroproteomics analysis module, which provided a comprehensive analysis strategy for in-depth exploration of the species composition and executive function of the microbiome.
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PNAS: changes in intestinal mucus may trigger ulcerative colitis
Time of Update: 2022-10-25
Using colon cell lines, they found that different levels of FUT8 altered the ratio of two different types of mucin secreted by the cells—mucin2 and Mucin5AC—that make up the scaffold of the mucus layer.
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PGG.SV of the Human Genome Structural Variation Database and Computational Analysis Platform
Time of Update: 2022-10-25
SV of the human genome structural variation database jointly developed by Professor Xu Shuhua's team from the School of Life Sciences/Institute of Human Phenomics of Fudan University, Zhang Guoqing, researcher from the Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, and researcher Fan Shaohua from the School of Life Sciences, Fudan University PGGSV/), titled "PGG.
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Four epigenetic clocks based on a small number of CpG loci showed that centenarians had a younger epigenetic age than their chronological age
Time of Update: 2022-10-25
"In the current study, we estimated the age of DNA methylation (DNAmage) using four epigenetic clocks based on small cpg from French centenarians and semi-supercentenarians (CSSC, n=214) and offspring of 90- and 100-year-olds (NCO, n=143) and the general French population (CG, n=149).
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Nature Genetics has found a range of DNA variants associated with dyslexia
Time of Update: 2022-10-25
Some associated genetic variants were also significant in one of the Chinese samples, suggesting that there are general cognitive processes that do not depend on language type in learning to read.
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The Yin Kun team from the Department of Environmental Health and Ecological Security, School of Global Health, Advanced Science, published a review...
Time of Update: 2022-10-25
In recent years, infectious diseases such as new crowns and monkeypox have emerged one after another, seriously affecting the healthy life of human beings. Nucleic acid-based molecular amplification
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Liu Kexuan's team at Nanfang Hospital published important research results in top international journals in the field of respiratory
Time of Update: 2022-10-25
Recently, Professor Liu Kexuan's team from the Department of Anesthesiology of Nanfang Hospital published a paper entitled "Gut microbiota-derived succinate aggravates acute lung injury after intestinal" in the form of a paper in the top international respiratory journal, European Respiratory Journal (Region I of Small Respiratory Diseases, Chinese Academy of Sciences, IF=33.
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Chinese scholars have made new progress in thermal/electrical integration rectification
Time of Update: 2022-10-25
The study shows that the new two-dimensional in-plane heterojunction device not only has the advantages of atomic thickness, wide bandgap and high mobility, but also significantly improves the thermal conductivity of the material in a specific direction under high-power working conditions, which can greatly reduce the temperature and thermal stress of high temperature hot spots without external cooling, effectively improving device performance and prolonging service life.
