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The best blood thinners to reduce the risk of bleeding
Time of Update: 2022-11-04
" A new study led by researchers at University College London made a large-scale comparison of direct oral anticoagulants (blood thinners) and found that the drug had the lowest risk of causing bleeding.
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Nature sub-journal: PAPP-A three-dimensional structure
Time of Update: 2022-11-04
Article Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism The complex between PAPP-A and STC2 is a macromolecule consisting of 3600 amino acids.
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The reprogramming of immune cells has been shown to fight melanoma
Time of Update: 2022-11-04
The results of the experiment show that protocells are able to efficiently deliver and reprogram human immune cells to develop towards a longer-lasting pro-inflammatory and potentially anti-cancer state.
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【Cell Storage】Cell technology may help humans live to 120 years old!
Time of Update: 2022-11-04
How old is a person's normal life expectancy?American microbiologist Leonardo ▪ Hayvlik found that human embryonic lung fibroblasts can only divide about 50 times, and then appear malformed, stop dividing, and die.
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The preaxial development pattern of limbs in the early evolution of quadrupeds is related to the formation of five fingers/toes
Time of Update: 2022-11-04
Fig. 4 Limb bone development and evolution patterns of quadrupedsFig. 5 Early quadruped pentafinger/toe formation, origin and ossification polarity comparison of distal carpal bone and tarsal boneThe work was published in Science Advances under the title "Ossification patterns of the carpus and tarsus in salamanders and impacts of preaxial dominance on the fin-to-limb transition.
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Professor Ren Changliang and his collaborators have made important progress in the construction of artificial transmembrane channels and their anti-cancer applications
Time of Update: 2022-11-04
Recently, the team of Professor Ren Changliang, School of Pharmacy, State Key Laboratory of Cell Stress Biology, Fujian Provincial Key Laboratory of New Drug Target Research, and the team of Professo
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How quickly fruit flies "count" odors, the new model tells you
Time of Update: 2022-11-04
”A neural theory for counting memories Imagine you're sitting at home and hear someone knocking on the front door.
”A neural theory for counting memories Imagine you're sitting at home and hear someone knocking on the front door.
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Holographic microscopes provide insight into plankton life
Time of Update: 2022-11-04
Using holograms made with digital microscopes and interpreted using artificial intelligence (AI), researchers can now track plankton life on an individual level for the first time.
Using holograms made with digital microscopes and interpreted using artificial intelligence (AI), researchers can now track plankton life on an individual level for the first time.
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The team of Xu Yikai of Nanfang Hospital has published a series of new results in internationally renowned academic journals
Time of Update: 2022-11-04
Recently, the research results of Professor Xu Yikai's team in the field of tumor molecular imaging and functional imaging of Nanfang Hospital have been published online in internationally renowned j
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The new technology solves the long-standing challenge of self-healing materials
Time of Update: 2022-11-04
This latest technology solves two long-standing challenges faced by self-healing materials and can significantly extend the life of structural components such as wind turbine blades and aircraft wings.
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A new live-of-life imaging method of light film of C. elegans adults
Time of Update: 2022-11-04
"In the 2021 embryology course, we set out to develop a technique that would allow us to image adults Caenorhabditis elegans to visualize worms over a longer period of time and at high resolution by using light-sheet microscopy," Wolf said.
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Nature Metabolism: Synthetic energy metabolism provides a dual engine for cells
Time of Update: 2022-11-04
Figure: Schematic of a twin-engine designA research team led by Professor YU Tao of the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences has proposed a new synthetic energy system that can support yeast cell growth and the production of highly reducible chemicals.
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Overcoming drug resistance to colon cancer treatments
Time of Update: 2022-11-04
The team used an optimized combination of tyrosine kinase inhibitors that attack cancer cells through a different pathway than chemotherapy.
The team used an optimized combination of tyrosine kinase inhibitors that attack cancer cells through a different pathway than chemotherapy.
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Artificial intelligence helped researchers design microneedle patches to restore hair in bald mice
Time of Update: 2022-11-04
“Machine Learning Guided Discovery of Superoxide Dismutase Nanozymes for Androgenetic Alopecia” Mice treated with manganese nanoenzyme microneedle patch have thicker hair regrowth (right image, labeled MnMNP) compared to mice treated with testosterone as control (left picture).
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Use 3D modeling to stop the spread of cancer
Time of Update: 2022-11-04
Ioannis Zervantonakis, assistant professor of bioengineering at Pitt University, and his team received a four-year, $792,000 grant from the American Cancer Society to understand the biology behind the cellular interactions that lead to ovarian cancer metastasizing to other parts of the body.
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Nature Methods: A new way to construct detailed maps of human tissue
Time of Update: 2022-11-04
However, "it is crucial for researchers to learn more about the details of the organizational structure; Fundamental changes in the relationships between cells within tissues drive the function of healthy and diseased organs," said senior author Dr Olivier Elemento, director of the England Institute of Precision Medicine.
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Attenuation evolution of mammals in the Cenozoic era
Time of Update: 2022-11-04
Certain lifestyles, such as aquatic habitats or herbivory, lead to faster changes, while in some species, such as rodents, morphological changes appear to be decoupled from taxonomic diversificationsummaryThe diversification of Cenozoic placental mammals is the prototype of adaptive radiation.
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Neuron's new view on the blood tumor barrier
Time of Update: 2022-11-04
Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity Huang's team, co-led by Chen Xin, Ali Momin and Siyi Wanggou of SickKids, found that medulloblastoma tumor cells rely on ion channels "pressure sensitive," a protein that plays an important role in cell signaling, to help form a blood-tumor-related barrier.
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PNAS Sleep Special: It is the brain, not age, that determines children's naps
Time of Update: 2022-11-01
Proceedings of the National Academy of Sciences, 2022; 119 (44) Why do some 4- and 5-year-olds still nap punctually every afternoon, while others start giving up habitual naps at age 3?There's no doubt that this is something that many parents are pondering, and one that sleep scientists at the University of Massachusetts Amherst have been pondering for years.
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Methylation of the young brain may be the key to obesity
Time of Update: 2022-11-01
A team of researchers reported in the journal Science Advances that neurons and glial cells in the mouse arcuate nucleus (the region of the hypothalamus that regulate energy balance) underwent sex-specific methylation changes.
