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Scientists discover potential "electrical language" for breast cancer cells
Time of Update: 2022-11-26
"We don't yet know why the voltage of cell membranes fluctuates in cancer cells, but our findings and technology, with exciting collaboration between engineers and biologists, opens the door to further work that could help us better understand cancer signaling networks and growth.
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Neutrophils overcome their ability to cluster by synergistic production of LTB4 across cellular biosynthesis
Time of Update: 2022-11-26
Transcellular biosynthesis of leukotriene B4 orchestrates neutrophil swarming to fungi Neutrophils require lipid mediator leukotriene B4 (LTB4) aggregation in response to fungal targets.
Transcellular biosynthesis of leukotriene B4 orchestrates neutrophil swarming to fungi Neutrophils require lipid mediator leukotriene B4 (LTB4) aggregation in response to fungal targets.
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Miniature "bone marrow in a petri dish" improves anti-cancer treatment
Time of Update: 2022-11-26
"Article Human bone marrow organoids for disease modelling, discovery and validation of therapeutic targets in hematological malignancies Image: Cross-section of a miniature bone marrow organoid showing platelet-producing cells in a vascular network.
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Popular dietary supplements can lead to cancer risk and brain metastases
Time of Update: 2022-11-26
” Elena Goun While previous studies have shown that commercial dietary supplements like nicotinamide riboside (a type of vitamin B3) have benefits for cardiovascular, metabolic, and neurological health, a new study from the University of Missouri found that NR actually increases the risk of serious diseases, including cancer.
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Genes have been found to be associated with most aggressive kidney cancers
Time of Update: 2022-11-26
After studying data from tumor samples from 456 patients, Grigory Puzanov, a researcher at the International Bioinformatics Laboratory at HSE's School of Computer Science, identified cancer subtypes associated with favorable or adverse processes of the disease.
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The research team of Wei Rui/Hong Tianpei of the Third Hospital of Peking University published the research results of the regeneration mechanism of islet β cells online in Diabetologia
Time of Update: 2022-11-26
The Wei Rui/Hong Tianpei research team first reported in iScience in 2019 that glucagon receptor (GCGR) monoclonal antibody (mAb) blocking glucagon signaling can induce transdifferentiation of islet α cells to β cells in mice with type 1 diabetes with absolute deficiency of β cells, thereby promoting β cell regeneration.
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Bacteria in tumors may promote cancer!
Time of Update: 2022-11-26
Soon after, Gregory Sepich Poore, a doctoral student in Rob Knight's lab of microbiome at UC San Diego, was looking for ways to diagnose pancreatic cancer early, and inspired by Straussman's 2017 paper, Sepich Poore began searching for fragments of microbial genetic material in the Cancer Genome Atlas, a large DNA database of human 。 Gregory Sepich Poore's grandmother died of cancer, which was diagnosed too late and treatment was ineffective.
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New insights into mitochondrial nucleotic dynamics
Time of Update: 2022-11-26
They demonstrated that ATAD3A is essential for active movement of mtDNA nucleioid within mitochondria — a process known as nucleoid "transport" — and that nucleoids aggregate abnormally in cells lacking mitochondrial fission.
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Researchers have solved a century-old mystery about plants
Time of Update: 2022-11-26
Hydraulic failure as a primary driver of xylem network evolution in early vascular plants The earliest terrestrial plants were small – only a few centimeters tall at most – growing in moist swampy areas around streams and ponds.
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Princeton University has discovered a new pathway for antimicrobial peptides
Time of Update: 2022-11-26
"It's a new way to discover natural products, where you start with biosynthetic gene clusters and then do an in-depth analysis of the reaction of each enzyme to understand all the different transformations that are happening," Covington said.
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Nature Communications Daniel Falush's group reveals how Helicobacter pylori "goes out of Africa"
Time of Update: 2022-11-26
On November 11, the international journal Nature Communications published online the title Repeated out-of-Africa expansions of Helicobacter pylori driven by replacement of deleterious mutations by Daniel Falush, a team of researchers at the Shanghai Pasteur Institute of the Chinese Academy of Sciences The research paper reports the unique evolutionary history of researchers discovering that new H.
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Roundup: How exactly do intracellular droplets work?
Time of Update: 2022-11-26
Tanja Mittag, a structural biologist at St. Jude's Children's Research Hospital in Memphis, Tennessee, said, "There are many fundamental biological processes that have papers showing that phase separation plays a role.
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The world's first clinical trial of new tumor immunotherapy for pet dogs: bringing breakthroughs to the treatment of children with cancer
Time of Update: 2022-11-26
Joost Leisterhuis, an associate professor and director of the Cancer Center at Telethon Children's Institute, said that the first step for almost all sarcoma patients after diagnosis is to surgically remove the tumor.
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A potential therapy to reduce chemotherapy side effects
Time of Update: 2022-11-26
Istrafilin, which has been approved for the treatment of Parkinson's disease, not only reduces the harmful effects of cisplatin, but also improves its anti-tumor properties.
Istrafilin, which has been approved for the treatment of Parkinson's disease, not only reduces the harmful effects of cisplatin, but also improves its anti-tumor properties.
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Squid love to play pranks and how big their brains are
Time of Update: 2022-11-26
"Our conclusion is surprising because much of what we know about vertebrate nervous system development has long been thought to be specific to this lineage," said Kristen Koenig, a distinguished researcher at John Harvard University and senior author of the study.
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How history affects the success or failure of ecological restoration
Time of Update: 2022-11-26
Image credit: Lars BrudvigBright spot:Ecologists at Michigan State University have shown that efforts to restore prairie can yield very different results in terms of biodiversity and function when the only variable is the year prairie was planted.
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The agglomeration of the transcriptional regulator SEUSS mediates the perception and response of Arabidopsis osmotic stress
Time of Update: 2022-11-26
essayCondensation of SEUSS promotes hyperosmotic stress tolerance in Arabidopsis Figure: SEU is essential for resistance to osmotic stressProfessor Fang Xiaofeng of Tsinghua University and Professor Lin Rongcheng of the Institute of Botany, Chinese Academy of Sciences jointly found that the transcriptional regulator SEUSS (SEU) plays a key role in plant hypertonic stress through polycondensation.
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Nature has recently discovered an antibiotic combination to reduce Staphylococcus aureus resistance
Time of Update: 2022-11-26
Article Antibiotic combinations reduce Staphylococcus aureus clearance Researchers at the Israel Institute of Technology (Technion) have developed a technique that can measure the long-term effects of antibiotic combinations or cocktails.
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The ITEWA team of Shanghai Jiaotong University proposed an energy harvesting strategy based on water vapor adsorption to achieve all-weather air water intake and temperature difference power generation
Time of Update: 2022-11-26
Recently, the ITEWA team of the Institute of Refrigeration and Cryogenic Engineering of Shanghai Jiaotong University published a research paper entitled "Simultaneous Atmospheric Water Production and
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SCI ADV: Identifies a specific regulator that promotes breast cancer development
Time of Update: 2022-11-26
27-hydroxycholesterol (27-HC, 27-hydroxy) is the most abundant oxysterol that increases the risk of breast cancer progression, but researchers do not currently know the epigenetic regulation of 27-HC
