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Primate-specific genes are involved in the cell cycle processes of the brain in cancer and embryonic stages
Time of Update: 2022-12-30
The Daniel Zhang research group and collaborators of the Institute of Zoology, Chinese Academy of Sciences explored the above questions by integrating data from The Cancer Genome Atlas (TCGA), brain development transcriptome [10] and primate-specific gene collection [11], and the relevant results were published in Genome Biology (GB) on December 6, 2022, with the paper "Pan-cancer surveys indicate cell.
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A novel ribosomes (RibosomeST) in spermatogenesis are capable of producing sperm-specific proteomes
Time of Update: 2022-12-30
On December 14, 2022, the team of Sha Jiahao and Guo Xuejiang of Nanjing Medical University and the team of Qin Yan of the Institute of Biophysics of the Chinese Academy of Sciences published the article "A male germ-cell-specific ribosome controls male fertility" in Nature, and found that the novel ribosomeST in spermatogenesis can produce sperm-specific 。Ribosomes are direct 20~30nm near-spheroids, and a wide range of ribosomes can be seen in high-resolution imaging of cells (Figure 2).
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The new combination of drugs holds promise for improved treatment of cervical cancer
Time of Update: 2022-12-30
A study led by the University of Texas Southwestern Medical Center has shown that a new combination of drugs slows the growth of cancer cells through an unexpected mechanism, which promises to improve the treatment of cervical cancer.
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Fudan University published a preprint: neutralizing antibodies that are effective against new crown mutant strains
Time of Update: 2022-12-30
The scientific research team composed of Wang Qiao's laboratory and Ai Di Weixin Biopharmaceutical of Fudan University School of Basic Medicine discovered a broad-spectrum neutralizing antibody XG005, which is highly effective against all domestic new crown mutant strains, and verified through experiments that it has super high neutralizing activity against various strains such as new coronavirus wild type, Alpha, Beta, Gamma, Delta, OmicronBA.
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Ma Renmin's research group realizes a high-quantum efficiency topological polarization singularity laser
Time of Update: 2022-12-30
The research group of Professor Ma Renmin, Institute of Condensed Matter Physics and Materials Physics, Nanophotoelectronics Frontier Science Center, and State Key Laboratory of Artificial Microstruc
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The maternal factor Nanog promotes a novel mechanism of fish oogenesis and egg quality through translational control
Time of Update: 2022-12-30
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Science Advances: Observation of the atomic structure of staphylococcal bacteriophages with cryo-electron microscopy
Time of Update: 2022-12-30
essayStructure and host specificity of Staphylococcus epidermidis bacteriophage Andhra Image: Andhra bacteriophageResearchers at the University of Alabama at Birmingham used cryo-electron microscopy to expose the structure of a bacterial virus in unprecedented detail.
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Nature Cancer has found why immunotherapy is ineffective for the most difficult breast cancers to treat
Time of Update: 2022-12-30
"essayBreast cancer cells survive chemotherapy by activating targetable immune-modulatory programs characterized by PD-L1 or CD80 Due to advances in cancer treatment, most forms of breast cancer are highly treatable, especially when detected early.
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The research team of the School of Pharmacy of Shanghai Jiaotong University published a review of the research progress of STING signaling pathway mediating the multiple mechanisms of the new crown
Time of Update: 2022-12-30
The antagonistic mechanism of viral proteins on STING pathway and the activation effect of host cells on STING pathway were discussed, the inflammatory abnormalities caused by continuous activation of STING during SARS-CoV-2 infection were emphasized, the antiviral effect of STING agonists on SARS-CoV-2 was summarized, and the potential application value of STING agonists as adjuvants in the development of new crown vaccines was summarized.
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Extending life is not the same as slowing down aging, and Nature questions three anti-aging treatments
Time of Update: 2022-12-30
1038/s41467-022-34515-y In a new study, German scientists delved into three treatments widely believed to slow down the aging process.
1038/s41467-022-34515-y In a new study, German scientists delved into three treatments widely believed to slow down the aging process.
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Nature Neuroscience | released the research results of the Chinese Brain Connectome Program and its big data resources for the first time
Time of Update: 2022-12-30
Figure 2: Comparison results of Chinese and Western brain function activation maps under seven classical cognitive task states The co-first authors of the paper are Ge Jianqiao, a lecturer at the Institute of Advanced Interdisciplinary Studies of Peking University, Yang Guoyuan, assistant professor of the Institute of Advanced Interdisciplinary Sciences of Beijing Institute of Technology, and Professor Gao Jiahong of Peking University as the corresponding author.
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Chinese scholars published the article Nature to reveal the key to male fertility: an unknown ribosome
Time of Update: 2022-12-30
" According to a mouse study published yesterday (Dec. 14) in the journal Nature, a newly discovered ribosome type appears to play a key role in male reproductive health, synthesizing and neatly and safely folding proteins in sperm in preparation for their arduous journey.
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Novel chemotherapy regimens reduce the risk of postoperative recurrence in patients with hepatocellular carcinoma
Time of Update: 2022-12-30
This study was selected for poster discussion at the 2022 American Society of Clinical Oncology Annual Meeting and published online on December 16 under the title "The Role of Postoperative Adjuvant FOLFOX Hepatic Arterial Perfusion Chemotherapy in Patients with Hepatocellular Carcinoma with Microvascular Invasion: A Multicenter, Phase III Randomized Controlled Study" in the Journal of Clinical Oncology, a top journal in oncology.
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Xi Qioran's research group in the School of Life Sciences cooperated with Xiaoyi's research group to reveal that PML nucleosomes recruited TRIM33 to regulate in mouse embryonic stem cells.
Time of Update: 2022-12-30
On December 16, 2022, Xi Qiaoran's research group and miserly research group of Tsinghua University published an online publication entitled "Recruitment of TRIM33 to cell-context specific PML nuclear bodies in mouse embryonic stem cells" in the journal The EMBO Journal regulates Nodal signaling in mESCs).
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Pei Jian's research group in the School of Chemistry Prog. Polym. SCI Review: Solution aggregation state regulation of conjugated polymers
Time of Update: 2022-12-30
Link to paper: The macroscopic photoelectric function of conjugated polymers is closely related to its microscopic multi-level assembly structure at different spatial scales, including chemical structure, conformational distribution, intermolecular interaction, chain arrangement, crystallization behavior, film morphology and other structural characteristics.
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The mouse genome database is included in the global core biological data resource
Time of Update: 2022-12-30
Guy Cochrane, Executive Director of GBC, said: "The announcement of this list will bring funders and biological data resources together to develop sustainability models that meet their needs and ensure that these data resources can continue to support the global research community.
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Nature Communications: Mechanism of abnormal cholesterol metabolism leading to osteoarthritis
Time of Update: 2022-12-30
Cholesterol-LRP3-SDC4 regulates the occurrence of OADr. Cao Chenxi and Dr. Shi Yuanyuan of the Department of Sports Medicine are the co-first authors of the paper, and Assistant Researcher Cheng Jin, Hu Xiaoqing and Ao Yingfang are the co-corresponding authors of the paper.
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The Tang Xueming team of Shanghai Jiaotong University reviewed the research and application progress of RNA interference technology for pest control
Time of Update: 2022-12-30
Recently, Tang Xueming's team from the School of Agriculture and Biology of Shanghai Jiao Tong University published a review article entitled "RNAi-based pest control: Production, application and the fate of dsRNA" in Frontiers in Bioengineering and Biotechnology 。 This paper comprehensively and systematically reviews the research and application progress of RNA interference technology for pest control, mainly including: (1) the synthesis and construction of dsRNA and large-scale production methods.
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The ultimate method of ancient Chinese medicine to treat the new crown virus - Hu Tu Medicine
Time of Update: 2022-12-30
For any of the people who originally belong to the first three conditions mentioned above, once such people have some kind of therapy - especially natural remedies - such as the intervention and use of our ancient Chinese medicine medical software "Digital Care App", even if there are some diseases in the body, its symptoms will gradually decrease, disappear and heal.
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Nature: Significant progress! Ursodeoxycholic acid, which was originally used to treat liver disease, is expected to be used to prevent new coronavirus infection
Time of Update: 2022-12-30
In a new study, researchers from research institutions such as the University of Cambridge in the United Kingdom and the Charité Inky in Berlin, Germany, looked at miniature organs, donor organs, ani
