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New insights into wound healing
Time of Update: 2021-09-20
"Researchers have revealed how GRHL3 activates a protein-coding gene called fascial actin binding protein 1 (Fscn1) during wound healing to loosen the adhesions between injured skin cells so that they can effectively migrate.
Our findings reveal GRHL3 How the abnormality of the /FSCN1/E-cadherin pathway plays a role in non-healing wounds requires further research .
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Zai Lab's Nirapali ovarian cancer first-line maintenance treatment indication approved in Hong Kong, China
Time of Update: 2021-09-20
Zele® is an oral poly(ADP-ribose) polymerase (PARP) inhibitor once a day .
Unlike other PARP inhibitors that have been approved in Hong Kong, Zele® does not require BRCA mutation or other biomarker testing before medication .
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The School of New Materials publishes a tutorial review article on the application of ion weighing technology in batteries in the "Chemical Society Review"
Time of Update: 2021-09-20
The electrochemical quartz crystal balance (EQCM) ion weighing technology is a powerful tool to achieve this goal, because it can study various phenomena of the battery under in-situ conditions, including ion insertion/deintercalation in the electrode, and The solid nucleation, formation of an interface / evolution and solid-like ligand .
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JAMA: Emojis allow patients and doctors to communicate better
Time of Update: 2021-09-20
Doctors at Massachusetts General Hospital believe that emoji (Emoji) is becoming a valuable tool in the medical field, allowing patients to better express symptoms, concerns, and other clinically relevant information .
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Newly developed software reveals the relationship between epitranscriptomics and cancer
Time of Update: 2021-09-20
Henry Young, scientists designed ModTect, a new computing software that can use existing sequencing data from clinical cohort studies to identify RNA modifications .
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eLife: Protect the microbiota necessary to fight antibiotic-resistant bacteria
Time of Update: 2021-09-19
The research results further prove that a healthy microbiome not only plays a key role in preventing or fighting infections, but also helps reduce the spread of resistant strains of harmful bacteria .
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Why do words become harder to remember with age
Time of Update: 2021-09-19
Martin said that there is a theory that as people age, they rely more and more on existing language knowledge, so communication between networks becomes the focus, while young people rely more on their fast working memory And cognitive control process .
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New technology aims to genetically control mosquitoes that spread diseases
Time of Update: 2021-09-19
Omar Akbari, Professor of Biological Sciences at the University of California, San Diego, said: “pgSIT is a new scalable genetic control system that uses a CRISPR-based approach to design deployable mosquitoes to suppress populations .
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New progress has been made in imaging research on the ratio of vertical and horizontal wave velocity in the ocean-continent transition zone of the Zhongsha block
Time of Update: 2021-09-19
In order to accurately determine the COT structure, the researchers took the COT on the south side of the Zhongsha block as an example, using active source submarine seismograph ( OBS ) detection data, proposed a set of S- wave crustal / upper mantle velocity structure inversion method, and obtained Vp /Vs model results .
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Scientists propose a new model: binge eating is not the main cause of obesity
Time of Update: 2021-09-19
The carbon water-insulin Model: A Physiological Perspective on The Obesity Pandemic, published in The American Journal of Clinical Nutrition The author of the book pointed out that the energy balance model has fundamental flaws, and believes that the carbohydrate-insulin model can better explain obesity and weight gain .
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Research on the source of CRISPR-Cas9 reveals a class of RNA-guided nucleases with genome editing potential
Time of Update: 2021-09-19
They discovered a class of transposon-encoded RNA-guided nucleases, which they called "OMEGA", which can be used for genome editing in human cells .
The CRISPR-Cas system has changed genome editing and other biotechnologies, however, the broad origins and diversity of these RNA-guided mechanisms remain largely unexplored .
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In order to protect the shea tree, scientists constructed a reference genome
Time of Update: 2021-09-19
The genome of the shea tree will allow researchers to assess the potential of the seedlings when they germinate.
Using the newly mapped genome, the researchers discovered 45 fatty acid biosynthesis genes in the shea tree, which may control the content of stearin .
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Researchers at UIC have discovered a link between herpes simplex and neuroreproductive diseases
Time of Update: 2021-09-19
A new study conducted by researchers at the University of Illinois Chicago (University of Illinois Chicago) shows that when optic nerve protein (OPTN) is present in cells, it can limit the spread of herpes simplex virus type 1 (HSV-1) .
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The relationship between standing and insulin sensitivity: standing more may help prevent chronic diseases
Time of Update: 2021-09-19
Researchers observed that standing is associated with better insulin sensitivity and is related to daily physical activity or sitting time and fitness level.
The results show that in terms of insulin sensitivity, the increase in body fat percentage is a more important factor than physical activity, health or sitting time .
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FDA-approved oral gout drug has powerful anti-COVID-19 virus properties
Time of Update: 2021-09-19
The study, published in Scientific Reports under the journal Nature , found that Probenecid (Probenecid) has a wide range of antiviral properties, making it an effective fight against SARS-CoV-2 infection and other common and deadly respiratory viruses, such as The drug of choice for RSV and influenza .
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Blood lipoprotein levels are linked to the risk of ALS in the future
Time of Update: 2021-09-19
A large epidemiological study published online in the Journal of Neurology, Neurosurgery and Psychiatry showed that some blood lipid biomarkers related to cardiovascular disease risk are also associated with lower risk of amyotrophic lateral sclerosis (ALS) Related .
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Thousands of tiny anchor points keep our cells in place. How is this done?
Time of Update: 2021-09-19
Maria Lastra Cargas, a PhD candidate of Science at the University of New South Wales School of Medicine and Health, said: "We have identified the proteins necessary for the function of these attachments .
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Nature Sub-Journal: Epigenetic changes in the elderly increase the risk of osteoporosis and fractures
Time of Update: 2021-09-19
"To clarify whether this change in the epigenome may also be the cause of the increased risk of fracture or osteoporosis in the elderly, the researchers studied human bone marrow mesenchymal stem cells from patients after hip surgery .
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Free radicals are related to heart damage caused by cancer and can be reversed by consuming specific antioxidants
Time of Update: 2021-09-19
Adding specific types of antioxidants to the food eaten by tumor-bearing fruit flies can reverse the damage to the heart-this finding suggests that the damage caused by free radicals may be a link between cancer and heart dysfunction .
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The research team invented an oral injection needle that is non-invasive and painless to achieve better efficacy
Time of Update: 2021-09-19
The test results show that for the needle injection depths of 3mm and 4mm, the drug dose is sometimes delivered to the mucosa instead of the submucosa.
