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Nature magazine reports that COVID-19 will accelerate cell aging
Time of Update: 2021-09-30
On this basis, the research team tried to link the host cell senescence caused by SARS-CoV-2 with Senolytics and develop new targeted treatment strategies for COVID-19 .
Therefore, Senolytics therapy for senescent cells can be used to eliminate SARS-CoV-2 infected cells and develop a new targeted therapy for COVID-19 .
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One-time gene therapy takes an important step to treat beta thalassemia
Time of Update: 2021-09-30
Reference materials:[1] bluebird bio Submits Biologics License Application (BLA) to FDA for betibeglogene autotemcel (beti-cel) Gene Therapy for Patients With β-thalassemia Who Require Regular Red Blood Cell Transfusions.
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Chinese scholar Science published breakthrough results: original research on artificial starch synthesis
Time of Update: 2021-09-30
Recently, Ma Yanhe's team from Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences has made breakthrough progress in the artificial synthesis of starch, and achieved the de novo synthesis of carbon dioxide into starch for the first time in the world .
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Studies have found that "Second-hand" psychological stress can cause depression in mice
Time of Update: 2021-09-30
One of the main authors of the study, Professor Akiyoshi Saitoh of Tokyo University of Science, further explained the motivation behind the study: "The number of people suffering from depression worldwide has been rising .
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Scientists discover key genes that regulate rice fertility and pool size
Time of Update: 2021-09-30
The study found that the PCD process of the tapetum cells of the post mutant anthers was inhibited, and the degradation of the tapetum was inhibited and delayed, leading to pollen abortion (Figure 1) .
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Blood cells: the future of drug delivery
Time of Update: 2021-09-30
EryDel's technology platform can also use the patient's own red blood cells to encapsulate proteins, which is expected to protect enzymes from immune responses and exert its expected therapeutic effects, thereby providing new treatments for rare enzyme deficiencies (a field with high unmet needs) .
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Japanese knotweed extract can reduce the carcinogenic risk of processed meat
Time of Update: 2021-09-30
In a paper published in "Molecular Nutrition and Food Research", an international team of scientists tested the comparison of this specially formulated product with traditionally processed red and white meat .
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Scientists have discovered that sterols are necessary for the accumulation of oil in plants
Time of Update: 2021-09-30
Professor Xu said: "We found that the lack of a special type of sterol can lead to a decrease in the accumulation of oil in seeds and leaves .
If a sample of plant tissue-leaves, stems or seeds-contains lipid droplets, they will turn into small green spots under a fluorescence microscope .
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Song Mingke's research group at Shanghai Jiaotong University proposes a new biomarker for Alzheimer's disease
Time of Update: 2021-09-30
Recently, the Song Mingke research group of the School of Basic Medical Sciences published a paper "Imaging asparaginyl endopeptidase (AEP) in the live brain as a biomarker for Alzheimer's Disease" in the Journal of Nanobiotechnology, the first to report that brain imaging analysis of asparaginyl endopeptidase (AEP) is expected to become A new biomarker for early diagnosis of AD .
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An inherited brain disease actually "counter-attacked" after birth
Time of Update: 2021-09-30
Our research in mice provides New information about the causes of abnormal behaviors related to the syndrome, and shows that it is truly possible to cure in the future .
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Genetic regulation of blood cells: proximity of genes to genetic changes plays an important role
Time of Update: 2021-09-30
Christiansen, Rick Jansen, Ilkka Seppälä, Lin Tong, Alexander Teumer, Katost Verlou Schramm, Gibran Hewlou, , Hanieh Yaghootkar, Reyhan Sönmez Flitman, Andrew Brown, Viktorija Kukushkina, Anette Kalnapenkis, Sina Rüeger, Eleonora Porcu, Jaanika Kronberg, Johannes Kettunen, Bernett Lee, Futao Zhang, Ting Qi, Arnin Jose Alquicira, Frank, Wibo Beutner, Peter AC ’t Hoen, Joyce van Meurs, Jenny van Dongen, Maarten van Iterson, Morris A.
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Nature: New research "sniffs out" how associative memory is formed
Time of Update: 2021-09-30
" Today, scientists agree that the medial temporal lobe, also known as the “memory center” of the brain, has discovered the structure responsible for the formation of associative memory, but the specific cells involved and how these cells are controlled have remained the same until now.
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Current Biology Yao Meng and Li Sheng's research group report based on DNA macrobarcoding to analyze the complex food web structure and species coexistence mechanism of a variety of carnivores in the mountains of southwest my country
Time of Update: 2021-09-30
The mountainous region of southwest China has the world's most diverse carnivore community (the photo is taken by the research team's infrared camera in the field) How carnivorous species coexist in the community in terrestrial ecosystems, and how to construct a complex food web structure between predators and prey, is one of the core issues of animal ecology research .
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Research finds ways to use radiation to convert organic waste into renewable biofuel additives
Time of Update: 2021-09-30
In a research paper titled "Renewable Fuel Additives for Organic Waste Produced by Nuclear Power" published in the scientific journal "Communication Chemistry", the engineers proposed a method for using biochemical and nuclear industry waste to produce this additive Sol The process of ketones, which is called nuclear refining .
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"One arrow and three eagles" for the treatment of solid tumors CAR-M therapy obtained FDA fast track qualification
Time of Update: 2021-09-30
Reference materials:[1] CARISMA Therapeutics Announces US Food and Drug Administration Grants Fast Track Designation to CT-0508 for the Treatment of Patients with Solid Tumors.
Retrieved September 22, 2021, from https:// -therapeutics-announces-us-food-and-drug-administration-grants-fast-track-designation-to-ct-0508-for-the-treatment-of-patients-with-solid-tumors-301381843.
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Scientists develop artificial intelligence methods to predict anti-cancer immunity
Time of Update: 2021-09-30
The pMTnet technology detailed online in "Natural Machine Intelligence" may lead to new methods for predicting cancer prognosis and potential responses to immunotherapy .
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Special transcription factors and their target genes are important ways to treat rare leukemias
Time of Update: 2021-09-30
BATF3 as an important transcription factor for signal transmission in anaplastic large cell lymphoma caused by a team of researchers Olaf Merkel of MedUni Vienna and Lucas Kenner (also at the Institute of Clinical Pathology at the Vienna Veterinary University) collaborative research The group's Stephan Mathas Max Delbrück Molecular Medicine Center Helmholtz Association (MDC), Charité-Universitätsmedizin Berlin and MDC's Experimental and Clinical Research Center (ECRC), and Charité have now tested the role of the transcription factor BATF3 in ALCL .
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Enhertu compared with enmetrastuzumab (T-DM1) reduces the risk of progression or death in patients with HER2-positive metastatic breast cancer by 72%
Time of Update: 2021-09-30
Based on the results of the DESTINY-Breast01 trial, DS8201 is approved in the United States, Japan, the European Union and several other countries for the treatment of unresectable or metastatic HER2-positive breast cancer adult patients who have received two or more anti-HER2 therapies .
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Thousands of clinical research sites get together and three major paths help global simultaneous R&D registration and review
Time of Update: 2021-09-30
The significant improvement in the time for the approval of innovative drug clinical research and registration and marketing applications has resulted in a significant increase in the number of innovative drugs (including Class 1 innovative drugs and overseas original research drugs) approved in China in recent years, which has approached the level of developed countries and regions .
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The research team of ANGEW Shanghai Institute of Medicine has constructed a diversified molecular framework of spiro heterocycles
Time of Update: 2021-09-30
The joint research team of Liu Hong and Zhou Yu of Shanghai Institute of Materia Medica, Chinese Academy of Sciences has long been committed to the efficient construction of spiro-ring dominant frameworks.
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