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Nature's intermittent fasting can make fruit flies live longer - is it useful for humans?
Time of Update: 2021-10-10
Mimi Shirasu Hiza, associate professor of genetics and development at Columbia University’s Vajlos College of Physicians and Surgeons, circadian rhythm expert, and leader of the study, said: “Because intermittent fasting limits the time to eat, some people assume that the natural biological clock is up.
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Technical serialization: Application of Cre-loxP site-specific recombination system in the study of conditioned target gene function in mice
Time of Update: 2021-10-10
The establishment of the Cre-loxP site-specific recombination system (Cre-loxP recombination system for short) provides an effective tool for perfecting the construction of gene-edited mouse models and further researching the function of conditional target genes .
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Chinese scholars have made progress in the study of fracture behavior of lamellar materials
Time of Update: 2021-10-10
Figure 1 The dominant fracture behavior of the lamella interface and the R T criterion Funded by the National Natural Science Foundation of China (92163215, 51731006, 5171093, 91860104), the research team of Professor Chen Guang from Nanjing University of Science and Technology has made important progress in the study of the fracture behavior of the lightweight, heat-resistant polymer twin TiAl single crystal high-performance material .
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Technical Serial No. 2: Application of Cre-loxP site-specific recombination system in the study of conditioned target gene function in mice
Time of Update: 2021-10-10
1. Influencing factors of Cre non-specific/error recombination/random insertion mutation At present, the commonly used Cre mouse models are mostly constructed by traditional transgenic technology, that is, the so-called cell/tissue-specific promoter partial DNA fragmentation strategy, coupled with random insertion of genes, may produce the so-called gene expression position effect and other characteristics, resulting in Cre expression The inaccuracies or leakage of, it is difficult to truly reflect the real desired specificity, resulting in off-target cleavage of Cre expression .
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Chinese scholars propose the next-generation ultra-high power density fuel cell technology route
Time of Update: 2021-10-10
This article points out the route for the research and development of the gas diffusion layer, catalytic layer, proton membrane and bipolar plate of the next-generation fuel cell.
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Novartis radioligand therapy for prostate cancer receives FDA priority review
Time of Update: 2021-10-10
Today, Novartis announced that the US FDA has accepted the company's new drug application (NDA) for the targeted radioligand therapy 177Lu-PSMA-617 and granted it priority review status for the treatment of metastatic castration-resistant prostate Cancer (mCRPC) patients .
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Use single nucleotide polymorphisms to identify pathways related to disease
Time of Update: 2021-10-10
Researchers at the University of Illinois Urbana-Champae (University of Illinois urbana-champae) have developed a new computational tool that can use single nucleotide polymorphisms to identify pathways related to disease, including breast and prostate cancer .
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The State Food and Drug Administration established the National Medical Device Clinical Evaluation Standardization Technology Center
Time of Update: 2021-10-10
See the table below for the list of the expert group of the first medical device clinical evaluation standardization technology focal point.
List of Expert Groups of the First National Medical Device Clinical Evaluation Standardization Technology Focal Point
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Pioneers of gene therapy bet on in vivo gene therapy of "larger gene fragments"?
Time of Update: 2021-10-10
On the same day, iCURE also announced a collaboration with the biotechnology company Precision BioSciences (hereinafter referred to as "Precision Bio", Nasdaq code: DTIL) to use the latter's ARCUS genome editing platform to develop allogeneic CAR-T and in vivo gene therapy .
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The application of the fungus team has made important progress in the genetic research of lentinus edodes population
Time of Update: 2021-10-10
Nanhu News Network (correspondent Shen Nan) Recently, a research team led by Professor Yinbing Bian from the School of Plant Science and Technology of our school used the population genomics method fo
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Cell Metabolism is a protein that is important for exercise coordination and performance
Time of Update: 2021-10-10
Jorge Correia, the first author of the study and a researcher in the Department of Physiology and Pharmacology of Karolinska Institutet, said: "There is still a lot of work to be done, but we believe this is important for patients with metabolic and neuromuscular diseases, such as Type 2 diabetes and amyotrophic lateral sclerosis (ALS) may have therapeutic value .
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Chinese scholars and foreign collaborators have made progress in the research of high-strength plastic gradient nano-dislocation structure high-entropy alloys
Time of Update: 2021-10-10
It is also superior to other graded nanocrystalline and graded nanotwinned structure metals and alloys in the literature; (CD) The HAADF-STEM results of the typical deformed structure when the tensile strain is 3% show that the plastic deformation of the graded dislocation structure passes through the unique ultra-high Density of sub-ten nanometers of stacking faults and a small amount of twin boundary coordination
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"The Lancet Psychiatry" published online the latest research by Professor Huang Yueqin's team from Peking University Sixth Hospital
Time of Update: 2021-10-10
9" >" The Lancet Psychiatry " published on September 21, 2021, "Study on the Epidemiology of the Prevalence of Depressive Disorders and Utilization of Health Services in China" led by Professor Huang Yueqin from Peking University Sixth Hospital .
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In vivo gene editing for treatment of congenital blindness Editas announces results of first human trial
Time of Update: 2021-10-10
Today, Editas Medicine announced the preliminary data of its in vivo gene editing therapy EDIT-101, a phase 1/2 clinical trial for the treatment of Leber congenital amaurosis 10 (LCA10) .
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Use the power of stem cells to create cartilage tissue
Time of Update: 2021-10-10
Researchers at the University of Southampton have invented a new method to generate human cartilage tissue from stem cells .
1038 / s41598-021-97934-9A scaffold-free approach to cartilage tissue generation using human embryonic stem cells
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The Institute of Zoology reveals the important role of innovation in predation behavior in the success of alien bird invasions
Time of Update: 2021-10-10
To this end, the Animal Invasion Ecology Research Group and the Bird Behavior, Function and Evolution Research Group of the Institute of Zoology, Chinese Academy of Sciences have cooperated with 9,899 successful colonization events and 2,370 failures of 247 exotic birds in 199 countries or regions around the world.
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iScience: Plant compounds can protect bees from deadly viruses
Time of Update: 2021-10-10
The research team discovered that sodium butyrate (NaB) is a compound found in many plants and is known to increase the expression of a variety of genes in animals, including those involved in immune response and learning .
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How sepsis is not fatal
Time of Update: 2021-10-10
"These biomarkers were found to have unique changes in the blood of patients with sepsis within 6 hours and affect specific cellular pathways in specific immune cells," said Nair, associate professor of biomedical sciences, who was published in " Co-leader of the research in the Journal of Leukocyte Biology .
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eLife: Rare immune cell cancer is related to bone marrow gene mutations
Time of Update: 2021-10-10
A study published in the journal eLife showed that mutations in blood cells that may be caused by smoking and aging-related changes may lead to a rare blood cancer that affects immune cells .
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Nature Microbiology Plasmodium falciparum evolves in Africa to avoid rapid diagnosis of malaria
Time of Update: 2021-10-10
Parr said: "We have found clear evidence that recently at the border between Ethiopia and Sudan and Eritrea, parasites have evolved to evade the rapid diagnostic test for malaria .
