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Two years later, Gene Editing Pioneer published several articles such as Cell: Leading editing efficiency increased by 10 times!
Time of Update: 2021-10-19
In order to further develop this technology, scientists at MIT and Harvard's Broad Institute have improved a key component of the lead editing system, which is called prime editing guide RNAs (pegRNAs).
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Science: How the brain filters interference signals to coordinate actions
Time of Update: 2021-10-19
Azim and colleagues want to understand exactly how a healthy brain screens, picking out the tactile signals it needs to consider to coordinate some dexterous actions, such as manipulating objects .
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Cell: Possible Alternative Therapy for Lyme Disease
Time of Update: 2021-10-19
Hygromycin A can eliminate mice ( Including animals that ingest the compound in the bait, Borrelia burgdorferi is infected, and the damage to the fecal microbiota is less than that of clinically relevant antibiotics .
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Researchers have discovered a protein that can prevent severe brain damage and reduce the risk of fatal HSV-1 infection
Time of Update: 2021-10-19
A new study by researchers at the University of Illinois at Chicago shows that a mechanism can prevent the herpes simplex virus from causing severe brain damage and death .
During herpes infection, mTORC2 activates the cell survival mechanism of the eye and neuronal tissues .
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Only a quarter of the Western Roman emperors died from the mathematical principles of natural causes
Time of Update: 2021-10-19
Researchers at the S?o Paulo School of Mathematics and Computer Science (ICMC-USP) in S?o Carlos (S?o Paulo State, Brazil) investigated the underlying mathematical patterns associated with the Roman emperor’s reign and showed that they followed statisticians The so-called "Power Law" .
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"Neuron" solves the mystery of our overeating
Time of Update: 2021-10-19
The Stuber laboratory studies the functions of the main cell groups in the brain's reward circuit and describes their role in addiction and mental illness, hoping to find a cure .
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Tang Fuchou and Li Tiejun's research team collaborated to develop a new method for integrating single-cell data based on molecular network features
Time of Update: 2021-10-19
(A) SCORE assumes that the transition of cell state is related to the activation/inhibition of molecular network functional modules, which can be inferred from single-cell transcriptome data .
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Supercomputer reveals how the X chromosome is folded and inactivated
Time of Update: 2021-10-19
"This is the first time we have been able to simulate all RNA that spreads around chromosomes and shuts them down," said a visiting scientist at Los Alamos National Laboratory, Massachusetts General Hospital and Harvard.
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Chinese scholars have developed a fiber-optic micro-force sensor to achieve nano-Newton-level weak force measurement
Time of Update: 2021-10-19
In response to this challenge, the research team used femtosecond laser two-photon polymerization nanolithography technology to 3D print a micro-sized fixed-supported beam probe-based micro-force sensing structure on the end face of a single-mode fiber for the first time .
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New method can reduce the side effects of antibiotic treatment
Time of Update: 2021-10-19
Recently, an international research team led by German scientists analyzed the effects of 144 antibiotics on common human intestinal bacteria and proposed a new method that can reduce the negative impact of antibiotic treatment on the intestinal microbiota .
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New technology shows early biochemical changes in tumors
Time of Update: 2021-10-19
Narasimhan Rajaram, associate professor of biomedical engineering, said: "We have demonstrated that spectroscopy can provide sensitive detection of early changes in tumor biomolecular composition .
In this study, researchers used machine learning methods to train hundreds of Raman data sets obtained from colon cancer tumors treated with different immunotherapy drugs .
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A collaborative team from the Institute of Zoology, Chinese Academy of Sciences found that seasonal patterns of climate change affect the outbreak of Brandt's vole populations in the grassland
Time of Update: 2021-10-19
A cooperative team led by researcher Zhang Zhibin from the Institute of Zoology, Chinese Academy of Sciences, established 24 large-scale ecological factor simulation experimental fences (fence size: 60 meters * 80 meters) in Maodeng Ranch, Xilinhot City, Xilin Gol League, Inner Mongolia, using Brandt's vole as research For the object (Figure 1), 12 fences were selected to study the impact of changes in climate change falling water patterns on the outbreak of Brandt's vole population (Figure 1) .
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New study accurately identifies patients with colorectal cancer through analysis of the composition of the microbiome
Time of Update: 2021-10-19
Colorectal cancer (CRC) is a challenging public health problem facing the global population. Successful treatment depends on the stage of the disease when the patient is diagnosed. Recently, researc
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Science: Cambridge University discovered why T cells can kill cancer cells again and again
Time of Update: 2021-10-19
Researchers at the University of Cambridge discovered how T cells-an important part of our immune system-continuously kill cancer cells in the process of hunting them, and constantly reload their toxic weapons .
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Solve a puzzling and delightful mystery: the mystery of rare cancers directly caused by HIV
Time of Update: 2021-10-19
A team led by scientists from the University of Pittsburgh School of Medicine and the National Cancer Institute (NCI) announced today in the journal Science Advances that they have discovered why doctors have not found T-cell lymphoma (or immune system cancer) in HIV-infected people.
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iScience: Losing this protein will make the appetite strong
Time of Update: 2021-10-19
In order to further study how the lack of XRN1 leads to leptin resistance and increased appetite, the scientists observed whether the activity of appetite-regulating genes in the hypothalamus has changed .
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A new study discovers the molecular basis of plant sugar transport
Time of Update: 2021-10-19
Bj?rn Panyella Pedersen said: "Combining these methods, we are not only able to identify the key elements of the transport cycle in STPs, but also provide new evidence for the conserved regulatory mechanism in the sugar porter family .
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Cancer Research: Using Raman spectroscopy to predict whether immunotherapy is effective
Time of Update: 2021-10-19
"Combined with machine learning, Raman spectroscopy is expected to change the clinical method of predicting response to treatment," Paidi said .
Raman spectroscopy and machine learning reveals early tumor microenvironmental changes induced by immunotherapy.
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Science Advances: Pain relief technology without side effects!
Time of Update: 2021-10-19
" Our research results show that it is actually possible to develop powerful and Analgesics without side effects have been a major challenge so far,” explains Mathilde Forney, a PhD student and the first author of this new pain study .
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Discovery of a new role for brain immune cells may have an impact on Alzheimer's disease
Time of Update: 2021-10-19
The researchers said that in addition to revealing a new aspect of human biology, these findings may have important implications for diseases related to cerebral small blood vessel diseases, such as cognitive decline, dementia, and stroke .
