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PNAS: Calculating the path of cancer
Time of Update: 2021-10-20
This tool was originally invented to understand the interaction between different mutations in proteins, and now McCandlish and his collaborators are using this tool to understand the complexity of cancer-related gene expression and chromosomal mutations .
They worked with McCandlish to apply his methods to the evolution of gene expression and cancer mutations .
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Microbiologists study the relationship between fermented soy products and human health
Time of Update: 2021-10-20
Assistant Professor of Biology, University of Texas at Arlington, Woo-Suk Chang A microbiologist at the University of Texas at Arlington is studying how fermented soy products affect human digestive health .
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Breaking the traditional view: connecting histones regulate the length and shape of chromosomes
Time of Update: 2021-10-20
Now, new research has determined a protein called junctional histone, which controls whether DNA is wound into long and thin chromosomes (consisting of many small loops) or short and thick chromosomes (consisting of fewer loops).
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A new mouse model reproduces the subtype-specific pathological transmission of tau protein
Time of Update: 2021-10-20
Figure: Tau fibrils from AD, CBD and PiD patients were injected into the brains of Tau 3R/4R mice, and Tau accumulation was stained with 3R Tau specific antibodies (upper image) and 4R Tau specific antibodies (lower image) .
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Yaoshi Xinghui has made breakthrough progress in the field of meta-universe
Time of Update: 2021-10-20
"CheerChat" provides simple voice matching function and intelligent voice translation technology in single or multi-person rooms, and builds high-quality content communities, relying on professional product technology and mature business models as support, providing users with audio online and voice social networking Provide more novel social scenes and more personalized entertainment experience .
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eLife: How do human disease-causing genes exist for a long time in the human body
Time of Update: 2021-10-20
Their research shows that these genes prevent adaptation (or the evolution of beneficial genes) from occurring in the genome, allowing them to survive longer in the human population by preventing themselves from being removed by selective scanning .
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Changes in the length of the menstrual cycle before menopause can predict the risk of heart disease
Time of Update: 2021-10-20
Combined with other menopausal-related characteristics and health measures, changes in cycle length can help clinicians predict which patients are at higher or lower risk of cardiovascular disease and recommend prevention strategies .
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Takeda Vonola Fumarate Green Tablets Approved for New Indication for Maintenance Treatment of Reflux Esophagitis
Time of Update: 2021-10-20
Shanghai, October 14, 2021/PRNewswire/ - Takeda China announced today that its innovative acid-suppressing drug, voronola fumarate, has been officially approved by the National Medical Products Administration (NMPA) for use in recurrent cases Maintenance treatment for patients with reflux esophagitis (Reflux Esophagitis, RE) .
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Personality traits related to the characteristics of Alzheimer's disease
Time of Update: 2021-10-20
The study combines data from the Baltimore Longitudinal Study of Aging (BLSA) and the work of a previously published meta-analysis that summarized 12 studies on personality and the neuropathology of Alzheimer's disease .
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"Nature" reported that leprosy was found in wild chimpanzees for the first time
Time of Update: 2021-10-20
The origin of the infection is not yet clear, but a research team led by the University of Exeter and the Koch Institute said that the results show that leprosy may be spread in more wild animals than previously suspected, due to contact with humans or Other unknown environmental sources .
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For the first time, it is proved that "nano silver" can also produce drug resistance!
Time of Update: 2021-10-20
A new study by the University of Technology Sydney (UTS) found that pathogens that form biofilms can evolve to survive nano-silver treatment .
This study proved for the first time that long-term nanosilver treatment increases the risk of recurring infections .
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Committed to "green storage" Fujifilm LTO tape emission reduction benefits recognized
Time of Update: 2021-10-20
Fujifilm, which aims to reduce carbon dioxide emissions in data storage to achieve "green storage", has been promoting the popularization of LTO tapes that can greatly reduce the environmental load*[2] .
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Wang Hongyan's team collaborates to reveal the mechanism by which macrophages regulate sugar metabolism and eliminate bacteria
Time of Update: 2021-10-20
student of Wuhan Institute of Virology, Chinese Academy of Sciences) from the Research Group of Wei Bin, Shanghai University ) Is the co-first author of this article .
1985338 Macrophages use the VEGFR3-AMPK signal axis to integrate sugar metabolism, inflammasome activation and pyrolysis, and phagocytosis of bacteria.
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A new approach to optimize dendritic cell tumor immunotherapy
Time of Update: 2021-10-20
Importantly, the researchers found that when integrins are turned off, dendritic cells start a gene expression program that allows them to better regulate T cell activation and tumor rejection .
By inhibiting these receptors, the anti-tumor response of dendritic cells becomes more effective .
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Cancer Cell: Molecular Atlas of Small Cell Lung Cancer Reveals Unusual Cell Types
Time of Update: 2021-10-19
"The most exciting thing we found is that there is a rare group of stem cell-like cells in these tumors, which are closely related to the patient's prognosis," explained Charles Rudin, an internal medicine scientist at MSK.
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Proof of Eshelby's Conjecture in Anisotropic Medium
Time of Update: 2021-10-19
The research was published online in the International Solid Mechanics flagship journal Journal of the Mechanics and Physics of Solids with the title " Solutions to the generalized Eshelby conjecture for anisotropic media: Proofs of the weak version and counter-examples to the high-order and the strong versions " .
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Chinese Academy of Sciences scholars discovered a new regulatory mechanism for starvation-induced ketone body production
Time of Update: 2021-10-19
On August 30, 2021, the international academic journal Molecular Metabolism published an online article "PAQR9 regulates hepatic ketogenesis and fatty acid oxidation during fasting by modulating protein stability of PPARα" by Chen Yan's research group, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences .
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Impaired white matter integrity in patients with Alzheimer's disease gene mutations
Time of Update: 2021-10-19
Prescott and his colleagues on patients with sporadic Alzheimer’s disease (accounting for 99% of cases) found that as the burden of amyloid protein in patients increases, through a method called diffusion tensor imaging (DTI) MRI technology measurement, the connectivity of the white matter structure is significantly reduced,Jeffrey R.
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[China Agriculture Net] Combining agriculture and animal husbandry to repair saline-alkali land
Time of Update: 2021-10-19
From October 9th to 10th, Huazhong Agricultural University and Jilin Research Institute of China Engineering Science and Technology Development Strategy held "Agriculture and Animal Husbandry, Restoration of Saline-alkali Land, and Soil Fertility Field Observation Seminar" in Changchun City and Baicheng City, Jilin Province .
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Make desalinated water safer and cheaper
Time of Update: 2021-10-19
Under the guidance of Professor Matthew Suss of the School of Mechanical Engineering and Technology, PhD students Amit Shocron and Eric Guyes, together with collaborators from Wageningen University and Wetsus, developed a new modeling technique that uses capacitive deionization to predict The behavior of boron in the desalination process .
