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Cancer Cell Zhang Zemin's research group and collaborators reveal the mechanism of action of anti-PD-L1 immunotherapy combined with chemotherapy in triple-negative breast cancer
Time of Update: 2021-10-20
October 14, 2021, Biological forefront of innovation Medical Center (BIOPIC) Peking University, College of Life Sciences, Beijing future genetic diagnosis sophisticated Innovation Center (ICG) Zhang
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Evidence that "mindful breathing" can be used to treat pain
Time of Update: 2021-10-20
Alexandre DaSilva , an associate professor at the School of Dentistry, said that they found that each one reduces pain by regulating the somatosensory cortex, which is the area of the brain responsible for processing pain, but each uses a different mechanism .
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Clarification of research contradictions: the relationship between diabetes and dementia risk
Time of Update: 2021-10-20
A longitudinal study by the Karolinska Institute in Sweden showed that poorly controlled type 2 diabetes mainly increases the risk of cognitive impairment and dementia, rather than diabetes itself .
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Global new coronary pneumonia treatment urgently needs a breakthrough
Time of Update: 2021-10-20
At present, the treatment of new coronary pneumonia has risen to be a strategic issue for advanced medical countries, and Eglin's new anti-inflammatory drug EG-009A is achieving breakthroughs through a six-point development strategy .
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The He Ming team of the School of Basic Medical Sciences reveals new mechanisms and new therapeutic targets for alcoholic liver disease?
Time of Update: 2021-10-20
On October 12th, the team of Professor Ming He from the Department of Pathophysiology and the Key Laboratory of Cell Differentiation and Apoptosis of the Ministry of Education, Shanghai Jiaotong University School of Medicine, published an online publication titled "SIRT2-mediated deacetylation and deubiquitination of C/EBPβ prevention" in Cell Discovery.
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Stem cell transplantation: how skin-derived T cells damage other organs
Time of Update: 2021-10-20
In skin samples from patients before and after transplantation, Stary and research author Johanna Strob were able to prove that host-derived T cells in the skin tissue are responsible for the inflammation .
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Eating mushrooms can reduce the risk of depression
Time of Update: 2021-10-20
Not only do they reduce the risk of cancer and premature death, but a new study led by the Pennsylvania State University School of Medicine also reveals that these superfoods may benefit people’s mental health .
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The asteroid hit the earth, why did the primate ancestors survive?
Time of Update: 2021-10-20
"Although primates live on trees, one possible explanation for how to survive across the K-Pg boundary may be due to certain behavioral flexibility, which may be a key factor for their survival," the first of the paper Said Jonathan Hughes, one of the authors and a PhD student in the laboratory of Jeremy Searle, Professor of Ecology and Evolutionary Biology at Cornell University's School of Agriculture and Life Sciences .
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Zhang Xinzheng's research team and Tsinghua University Xiang Ye's research team cooperated to reveal the Venezuelan equine encephalitis virus binding receptor...
Time of Update: 2021-10-20
On October 13, 2021, " Nature " magazine published online the research paper "Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3", which was completed by Zhang Xinzheng's group of Institute of Biophysics of Chinese Academy of Sciences and Xiang Ye's group of Tsinghua University School of Medicine.
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The "Science" single domain antibody TB202-3 has shown effective binding to a variety of SARS-CoV-2 strains in preclinical studies, including α, β and γ strains
Time of Update: 2021-10-20
Leproust continued: "These comprehensive results indicate that TB202-3 may be more resistant to receptor-driven selection pressure, and Twist antibody may have a therapeutic effect on the emerging SARS-CoV-2 mutation .
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Nature: Leuven University has developed a very effective antiviral drug for dengue fever
Time of Update: 2021-10-20
Photo: Researchers from the Riga Institute of Leuven University and CD3 have developed a super-strong dengue virus inhibitor, which causes a tropical disease called dengue fever .
"The team and Professor Xavier de Lamballerie (University of Aix-Marseille) demonstrated that this antiviral drug is very effective against all known dengue virus variants .
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How long do you sleep at night?
Time of Update: 2021-10-20
Compared with sustained normal sleep duration, sustained short sleep duration at 50, 60, and 70 years of age is also associated with a 30% increased risk of dementia, independent of socio-demographic, behavioral, and cardiometabolic factors.
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Tianjing Biotech announces the progress of multiple registered clinical studies on the differentiated CD38 antibody fezetuzumab
Time of Update: 2021-10-20
The clinical research data will support the company's submission of a biological product marketing application (BLA) for the second-line treatment of multiple myeloma in China .
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Zhou Bin's group reveals the differentiation potential of adult Sca1+ endothelial progenitor cells
Time of Update: 2021-10-20
Using this specific mouse, the researchers tested the differentiation potential of Sca1 + endothelial progenitor cells under physiological conditions, cardiac aortic stenosis-induced fibrosis, and femoral artery injury models .
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PNAS: a key gene that leads to cancer resistance
Time of Update: 2021-10-20
Thang Van Nguyen, an assistant research professor and lead researcher at the Precision Medicine Center, discovered that a protein called USP15 is highly expressed in cancer cells and is resistant to standard immunomodulatory drugs .
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Obesity Magazine Announces Groundbreaking Research in 2021
Time of Update: 2021-10-20
"Policies to address discrimination and bullying weight: from six countries Views on adult participation in weight management""Sex Dimorphism in Cardiac and Aerobic Capacities: The Influence of Body Composition," Candela Diaz-Cañestro, PhD, University of Calgary, Canada.
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Unusual kidney cancer characteristics reveal how cancer invades and metastasizes
Time of Update: 2021-10-20
In a study published in the journal Nature Communications, they showed that invasion involves the transient activation of an abnormal cell fate program, and it is not always the most evolved and aggressive tumor Sexually driven subpopulations of cancer cells (also called clones) .
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The first neuroscientific evidence that team mobility is a unique brain state
Time of Update: 2021-10-20
The research team led by Mohammad Shehata, an associate professor at Toyohashi University of Technology and Science, worked with researchers from California Institute of Technology and Tohoku University to discover brain waves and areas that are sensitive to team flow compared to non-participating teamwork or individual heart flow .
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Maternal stress "memory" affects grandson's biology
Time of Update: 2021-10-20
Researchers led by Wiener Prallard, associate professor of the Department of Biology and the Aging Mind and Brain Initiative, observed how nematode mothers react when they feel danger, such as temperature changes, which are harmful or even fatal to animals .
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Gan Lai will report the clinical and pre-clinical data of four non-alcoholic steatohepatitis pipelines in the form of oral reports or posters at the 2021 American Association for the Study of Liver Disease Annual Meeting
Time of Update: 2021-10-20
A PHASE Ib STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF ASC41, A THR-β AGONIST, FOR 28-DAYS IN OVERWEIGHT AND OBESE SUBJECTS WITH ELEVATED LDL-C, A POPULATION CHATERISTIC OF NAFLDReport format: poster presentation Abstract number: 1851 Conference theme: NAFLD and NASH: Clinical research presentation time: November 12, 2021, Friday, 6:00-11:55 AM EST Key information:-The liver-targeted prodrug ASC41 is a small molecule, highly effective and selective thyroid hormone Beta receptor (THR-Beta) agonist.