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New evidence for a link between herpes simplex (aphtha) and neurodegenerative diseases
Time of Update: 2021-10-21
A new study conducted by researchers at the University of Illinois Chicago (University of Illinois Chicago) shows that when optic neuroprotein (OPTN) is present in cells, it can limit the spread of herpes simplex virus type 1 (HSV-1) .
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FDA suspends CAR-T clinical trials based on gene editing
Time of Update: 2021-10-21
This paper in the journal Nature Genetics pointed out that DNA double-strand breaks introduced during the CRISPR-Cas9 gene editing process may cause chromosomes to fragment .
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Gale will report the results of the ASC22 (Envolimab) chronic hepatitis B phase IIa study at the 2021 American Association for the Study of Liver Diseases Annual Meeting
Time of Update: 2021-10-21
(Hong Kong Stock Exchange code: 1672) today announced its subcutaneous injection of PD-L1 antibody ASC22 (Envolimab) chronic type B The results of the phase IIa hepatitis study will be reported in the form of an oral report at the 2021 American Association for the Study of Liver Diseases (AASLD) Annual Meeting (The Liver Meeting® 2021) .
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Chinese scholars and overseas collaborators have made progress in the research of novel non-Hermitian acoustics and sound field control
Time of Update: 2021-10-21
Figure 1 Non-Hermitian topology phononic crystal construction and phase control Under the support of the National Natural Science Foundation of China (approval number: 11922407, 12074183
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The José C. Pastor-Pareja research team of the School of Life Sciences solved the decades-old mystery of how insect wings flatten
Time of Update: 2021-10-21
5 h to 22 h APF) In order to further study how cable-like cytoskeletal protrusions assemble and disaggregate, the Pastor-Pareja research group carried out genetic screening experiments for cytoskeleton-related proteins in Drosophila wings .
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vTv Therapeutics' breakthrough type 1 diabetes therapy mechanism research achieves positive results
Time of Update: 2021-10-21
On October 12, vTv Therapeutics announced that the study of the mechanism of TTP399 in the treatment of type 1 diabetes has obtained positive results, proving that patients with type 1 diabetes who received TTP399 did not have an increase in keto acid levels during the withdrawal of insulin treatment compared with the placebo group, which means that TTP399 does not Increase the risk of ketoacidosis .
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Li Peng Laboratory of the School of Life Sciences reveals that gel-like two-dimensional phase separation mediates lipid droplet interaction, lipid droplet fusion, and lipid homeostasis regulation
Time of Update: 2021-10-21
The author found that Cidec, an important protein that regulates lipid droplet fusion, can pass through the gel through biochemistry, cell biology, super-resolution imaging systems, and biophysical modeling methods.
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Scientists can initiate the response of plants to light
Time of Update: 2021-10-21
Under light conditions, phytochrome B inhibits the stability and activity of PIF3, slows down its growth rate and shortens seedlings .
"Chen's team demonstrated that by reducing the activity of the PIF protein, they can slow the growth of stems .
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Chinese scholars have made progress in the research of Fermi steady-state superradiation quantum phase transition
Time of Update: 2021-10-21
The strong coupling between the cold Fermi atoms and the optical cavity makes the steady-state superradiation quantum phase transition of Fermi atoms observed for the first time, revealing the role of Fermi atom statistics in the steady-state superradiation quantum phase transition .
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Scientists have discovered a highly effective antibody with 4-6 months of protection against SARS-CoV-2
Time of Update: 2021-10-21
The newly identified antibody was isolated from the lymphocytes of COVID-19 patients who participated in the immunization coronavirus research conducted by CHUV's Immunization and Allergy Service Center .
This means that the antibody prevents the virus replication process, allowing the patient's immune system to clear SARS-CoV-2 from the body .
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Break the tumor's protective barrier
Time of Update: 2021-10-21
The new treatment concept presented here ensures that the tumor cells themselves produce CD47 blocking and immune activating proteins .
005Article titleCD47-targeted cancer immunogene therapy: secreted SIRPα-Fc fusion protein eradicates tumors by macrophage and NK cell activation
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New advances in DON-induced muscle cell damage and accurate detection of major derivatives
Time of Update: 2021-10-21
On October 1, 2021, the international academic journal Ecotoxicology and Environmental Safety published an online publication titled "Mycotoxin deoxynivalenol affects myoblast differentiation via downregulating cytoskeleton and ECM-integrin-FAK-RAC-PAK signaling" by the Wu Aibo research group of the Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences.
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Using demographic data to assess the cumulative cancer risk caused by tap water pollution
Time of Update: 2021-10-21
EWG researchers applied this new framework to assess the cancer risk from a toxic mixture of tap water pollutants in California and Texas, where more than one-fifth of American residents live in these two states .
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The José C. Pastor-Pareja group of the School of Life Sciences reported on the structure of the endoplasmic reticulum-Golgi apparatus in Drosophila
Time of Update: 2021-10-21
Pastor-Pareja research group of the School of Life Sciences of Tsinghua University published a titled "There are a large number of vesicles and beaded tubules at the exit of the endoplasmic reticulum of fruit flies, but no "ER exit sites in Drosophila display abundant ER-Golgi vesicles and pearled tubes but no megacarriers)".
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The study found that Alzheimer's disease and the new coronavirus have a common genetic risk factor
Time of Update: 2021-10-21
PhD student Naciye Magusali (British Dementia Research Institute, University College London) said: “Our research shows that regardless of age, some people may be more susceptible to Alzheimer’s disease and severe Covid-19 because of some of our immune systems.
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The charge properties of the gas-liquid interface determine the protein orientation advantage of cryo-electron microscopy
Time of Update: 2021-10-21
Li Bufan, Zhang Xinzheng's research group from the Institute of Biophysics, Chinese Academy of Sciences, conducted mechanism research on the common protein dominant orientation problem in cryo-electron microscopy three-dimensional reconstruction, and found that the protein is adsorbed on the gas-liquid interface, and its orientation is controlled by the charge carried by the gas-liquid interface (Figure) .
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Idorsia Fabry disease trial failed oral therapy lucerastat uncertain future
Time of Update: 2021-10-21
CompilationFan DongdongA few days ago, Itorsia reported that the candidate oral therapy lucerastat failed to meet the primary endpoint, and the clinical trial for the treatment of Fabry disease was declared a failure .
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Drug Y officially landed in Jiahui International Cancer Center and became a pioneer in the use of dual immunotherapy in China
Time of Update: 2021-10-21
Shanghai, October 12, 2021/PRNewswire/ - On June 10, 2021, the first CTLA-4 inhibitor ipilimumab in China was approved by the China National Medical Products Administration (NMPA) to join Navuriu Mono
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Peking University Yao Maosheng's team has developed a non-invasive rapid screening technology for new coronary pneumonia based on the fingerprint of exhaled breath volatile organic compounds
Time of Update: 2021-10-21
Recently, Professor Yaosheng from the School of Environmental Science and Engineering of Peking University and Beijing Chaoyang District Center for Disease Control and Prevention and other cooperative teams have integrated exhaled breath sampling, gas chromatography-ion mobility spectrum detection and machine learning models to develop a non-invasive exhalation screen for new crown infections.
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Xiong Wei's research group from the School of Life Sciences published a report on a mouse model of deafness caused by ectopic insertion of a retrotransposon
Time of Update: 2021-10-21
On October 5, 2021, the Proceedings of the National Academy of Sciences (PNAS) published an online publication titled "An L1 retrotransposon insertion induced deafness mouse model for studying" The development and function of the cochlear stria vascularis" research paper elaborated on a mouse model of deafness in which the development of stria vascularis caused by retrotransposon L1 is impaired .
