-
Gut Wars: How the Human Microbiota Fights Cholera Bacteria
Time of Update: 2021-10-22
Studies have shown that intestinal pathogens need to interact with bacteria in the gut microbiota-ranging from competition for nutrients to full-scale bacterial warfare in order to gain a foothold in this environment .
-
Toxic fatty acids may become a new target for the treatment of neurodegenerative diseases
Time of Update: 2021-10-22
"Our findings indicate that the toxic fatty acids produced by astrocytes play an important role in brain cell death, providing a promising new target for treatment, and even preventing, many neurodegenerative diseases," said Shane Liddelow , PhD, who is the second author of the article and the corresponding researcher's paper published in the book "Nature" .
-
Potential "first-in-class" targeted protein degradation agents enter the clinic
Time of Update: 2021-10-22
On October 6, 2021, Dialectic Therapeutics announced that the first-generation compound DT2216, constructed based on its proprietary new anti-apoptotic protein targeted degradation technology (APTaD), has completed the first patient administration in a phase 1 clinical trial.
-
Do you think the census is difficult?
Time of Update: 2021-10-22
CSHL professor Anthony Zador's laboratory developed MAPseq to describe how different brain cells connect and interact .
He and his laboratory developed qBrain, a method that combines brain imaging technology to map the cells and connections in the primary motor cortex of mice in three dimensions .
-
Zhao Qing's research group has made important progress in the study of methoxyflavonoid metabolism in Scutellaria baicalensis Georgi
Time of Update: 2021-10-22
On September 7, 2021, Plant Biotechnology Journal published an online publication titled "Two types of O-methyltransferase are involved in biosynthesis of anticancer methoxylated 4′-deoxyflavones in Scutellaria baicalensis Georgi" by Zhao Qing's research group from the Center for Excellence in Molecular Plant Science, Chinese Academy of Sciences .
-
Benefit more cancer patients. This method allows the immune cells to be fully fired.
Time of Update: 2021-10-22
For example, only about 25% of patients with non-small cell lung cancer can respond optimistically to ICI .
In a patient with an excellent response to ICI, the T cells in his body that respond to cancer proteins have reprogrammed their transcriptomes into complete tumor killer cells .
-
Science explains the white matter of the brain
Time of Update: 2021-10-22
However, the Hebrew University research team was the first to use Nissl-stained brain slices to reveal fiber pathways in the white matter .
Researchers realized that by using simple computational tools in the field of image processing, they could use the pattern of cell organization to reveal the structure of white matter .
-
Hidden Problem-Orphans in the U.S. Coronavirus-19 Pandemic
Time of Update: 2021-10-22
The authors of the study estimate that 120,630 children in the United States have lost their primary caregivers (parents or grandparents who provide housing, basic needs and care) due to covid-19-related deaths .
-
Viagra's "cousin" reduces obesity by stimulating cells to burn fat?
Time of Update: 2021-10-22
"What's exciting is that, We have discovered an oral drug that can activate fat burning in mice and reduce obesity and fat accumulation in disease-causing organs such as the liver and heart; this is new .
To test the effects of PDE9 inhibitors on obesity and cardiometabolic syndrome, the researchers asked mice to eat high-fat foods.
-
New research shows the link between poor eyesight in children and learning and development
Time of Update: 2021-10-22
Research highlights the link between uncorrected poor vision and children's potential DALLAS, October 4, 2021/PRNewswire/ - Vision Impact Institute, EdGuard Institute, and Essilor's Vision for Life™ Social Impact Fund collaborated on a new study , It provides new insights into the correlation between uncorrected poor vision and children’s abilities, learning and behavior .
-
Cell Metab Shanghai Institute of Drugs analyzes the new molecular mechanism of mitochondrial homeostasis in non-alcoholic fatty liver disease and proposes original innovative drug targets
Time of Update: 2021-10-22
On October 5, 2021, the Shanghai Institute of Materia Medica Li Jingya and Tan Minjia's research team, together with the Gao Xin/Xia Mingfeng team of Zhongshan Hospital of Fudan University Affiliated Hospital, published the title "DRAK2 aggravates nonalcoholic fatty liver disease progression through SRSF6 on Cell Metabolism .
-
China's trip to the moon surprisingly reveals recent volcanic activity
Time of Update: 2021-10-22
According to the samples returned by the Apollo and Moon Project, scientists have evidence that the time of volcanic eruptions on the moon can be traced back more than 4 billion years ago, most of which occurred between 3.
-
Cell Research: Customize personalized medicine by measuring cancer cells
Time of Update: 2021-10-22
In recent years, Manalis and Ligon have been working on a new method of predicting patient response based on measuring the response of tumor cells to treatment rather than genomic characteristics .
-
The co-authored paper by Professor Dun Jia from HSBC Business School was officially accepted by the American Economic Review
Time of Update: 2021-10-22
9" >Recently, the paper Dynamic Price Competition, Learning-By-Doing and Strategic Buyers by Professor Jia Dun from the HSBC Business School of Peking University and his collaborators was officially accepted by the top international economics journal American Economic Review and will be published soon .
-
The 10,000-year-old evolution of hepatitis B virus
Time of Update: 2021-10-22
All the ancient HBV strains found in western Eurasia after this period belong to the new virus lineage that is still circulating in the region today .
-
How to protect privacy while sharing treatment information to speed up research
Time of Update: 2021-10-22
SAIL co-founder and Massachusetts Institute of Technology (MIT) professor Manolis Kellis hopes to save researchers from negotiating with hospitals to obtain data to run machine learning algorithms .
-
Multiple Nature papers: Neuroscientists complete the first comprehensive brain cell atlas
Time of Update: 2021-10-22
A large number of new studies have shown that the area of the brain responsible for initiating this action-the primary motor cortex that controls the action-has as many as 116 different types of cells that work together to make this action happen .
-
The Institute of Zoology has cooperated to reveal the route and mechanism of the rapid expansion of the distribution area of China's main domestic pest-Yellow-breasted rat to the north
Time of Update: 2021-10-22
In order to explore the routes and patterns of the proliferation and invasion of Yellow-breasted rat, reveal the impact of low-oxygen adaptability on the successful invasion of plateau areas and replace the original Rattus norvegicus in the marginal areas of plateaus, the research team used a series of methods such as genome and transcriptome The invasion mechanism of Yellow-breasted rat and the molecular basis of its adaptability to high altitude hypoxic environment were studied .
-
Science: A method to improve deep brain stimulation in Parkinson's disease
Time of Update: 2021-10-22
Spix and colleagues developed a deep brain stimulation (DBS) method that focuses on specific neural circuits and produces lasting effects in mouse models of Parkinson's disease .
-
Small molecules with dual functions
Time of Update: 2021-10-22
Researchers from the excellent cluster of "Microcosmic Balance" at Friedrich Schiller University in Jena are investigating how cholera bacteria manage to disrupt the intestinal balance while producing a pathogenic toxin .
"Our research shows that the production of toxins and the pathogenic properties of cholera bacteria are directly related to its metabolism," Papenfort said .
