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Potential new strategies to combat urinary tract infection (UTI)
Time of Update: 2021-11-03
Mysorekar said: "Through the animal model of UTI, we proved that DMF can activate NRF2, suppress the immune response, limit the damage caused by bacteria to urothelial cells, and promote the activation of RAB27B, thereby removing bacteria from the bladder .
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Published two "NAR" in a row, artificial chromosome research provides new ideas for gene therapy
Time of Update: 2021-11-03
These studies provide in-depth understanding of the mechanisms of DNA assembly and new centromere formation, and promote the cloning and gene therapy engineering of ACs .
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Nature Methods technological breakthrough: Use sound to "observe" a single cell?
Time of Update: 2021-11-03
In their latest paper, the research team describes how the technology’s sensitivity can be increased to such an extent that it is now possible to image individual cells carrying acoustic reporter genes in human tissues .
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Potential immunization strategies to prevent future coronavirus outbreaks
Time of Update: 2021-11-03
When the improved RBD vaccine is used to immunize mice, it mainly induces antibodies to recognize the core-RBD region of SARS-CoV-2 and other sars-related viruses, such as SARS-CoV or WIV1-CoV .
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Molecular mechanism of Plasmodium falciparum encoding super large membrane protein VAR2CSA to recognize placenta and tumor cells
Time of Update: 2021-11-03
On October 19, the international academic journal Cell Discovery published online a collaborative research paper by Wang Lanfeng's group, Jiang Lubin's group, Fudan University's Chen Zhenguo's group at the Shanghai Pasteur Institute of Chinese Academy of Sciences, and Associate Research Fellows Yang Xiuna and Gao Yan of Shanghai University of Science and Technology: The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum .
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Twist Bioscience launches exome 2.0 for genomics research
Time of Update: 2021-11-03
Twist Bioscience Corporation (Nasdaq: TWST (TWST) uses its silicon platform to provide high-quality synthetic DNA, today announced the launch of Exome 2.
0, which not only covers the genome of protein coding and non-coding regions more comprehensively, but also has first-class performance that can be reduced Downstream sequencing cost .
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"The Lancet" common antidepressants may have a fatal risk in the treatment of dementia
Time of Update: 2021-11-03
The study, led by the University of Plymouth and published in The Lancet, showed that the antidepressant mirtazapine has no effect on anxiety in patients with dementia and may be more likely to be associated with mortality than no intervention at all .
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Science sub-journals put forward a new view: red blood cells can activate the innate immune system
Time of Update: 2021-11-03
" For example, in 2018, her team showed that red blood cells use TLR9 to clear cell-free mitochondrial DNA.
They found that the cell membranes of these cells have changed, showing strange shapes, exposing more TLR9 nucleic acid binding domains, which may explain the increase in patient blood samples .
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Viral infection promotes neurodegeneration
Time of Update: 2021-11-03
Their assessment is based on laboratory experiments in which they were able to prove that certain viral molecules promote the cell-to-cell spread of protein aggregates, which are a hallmark of brain diseases such as Alzheimer's disease .
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The epidemic and centralized procurement are both suppressing the rules of the game in the equipment industry are quietly changing
Time of Update: 2021-11-03
The Mindray Medical report shows that the acquisition of Seatide Bio is aimed at strengthening the core research and development capabilities of chemiluminescence immune products and raw materials, optimizing the global layout of the upstream and downstream industrial chain, and laying the foundation for the globalization of the company's in vitro diagnostic business .
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Research on DNA repair promotes the development of gene editing technology
Time of Update: 2021-11-03
Now, the Princeton University researcher Britt Adamson of the new research laboratory, the Jonathan Sman Whitehead Institute member who conducted the laboratory with the collaborators, the MIT Insittute Professor of Biology and the Howard Hughes Medical Institute researcher , And Cecilia Cotta-Ramusino, this book details a new method called Repair-seq, which reveals in detail how genome editing tools work .
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BeiGene and Nanolek announced that Baiyueze(R) (Zebutinib) was approved in Russia for the treatment of patients with relapsed or refractory mantle cell lymphoma
Time of Update: 2021-11-03
Beijing, China, Cambridge, Massachusetts, and Moscow, October 20, 2021/PRNewswire/ - BeiGene (Nasdaq: BGNE; Hong Kong Stock Exchange: 06160) is a scientifically based global bio A technology company that focuses on the development and commercialization of innovative drugs worldwide to improve treatment effects and access to drugs for patients around the world .
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Nature Genetics: Single-cell multi-omics technology directly hits the powerful recovery ability of brain tumors
Time of Update: 2021-11-03
The researchers reported in the journal Nature Genetics that they used advanced technology to record gene mutations, gene activity, and DNA methylation in individual tumor cells collected from patients with glioma (the most common type of brain cancer).
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Watching TV shows to treat amblyopia?
Time of Update: 2021-11-03
Today, Luminopia announced that the US FDA approved its Luminopia One system as a prescription therapy to improve the vision of children with amblyopia .
Reference materials:[1] Luminopia Announces FDA Approval of Digital Therapeutic that Uses TV Shows to Improve Vision in Children with Lazy Eye.
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Lancet: Why does sitting for a long time easily lead to depression?
Time of Update: 2021-11-03
A study published in the internationally authoritative medical journal "The Lancet Psychiatry" shows that sitting for a long time increases the risk of depression in young people .
Questionnaire survey data indicate that physical activity and sedentary behavior may be related to the occurrence of depressive symptoms in adolescents .
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New cancer treatments may wake up the immune system
Time of Update: 2021-11-03
Researchers at the Massachusetts Institute of Technology have now discovered a new way to activate the immune system to attack tumors, which they hope will allow immunotherapy to treat more types of cancer .
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The world’s first case: a gene-edited pig kidney was transplanted to a human
Time of Update: 2021-11-03
For decades, people have been seeking to one day use animal organs in life-saving transplant operations, and this is just one small step .
The company focused on the use of pig organs for human xenotransplantation .
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Breakthrough results point to the deadliest brain cancer
Time of Update: 2021-11-03
This work, funded by the brain tumor research charity, may pave the way for patients diagnosed with glioblastoma multiforme (GBM) to provide truly personalized treatment .
In a trial involving 10 patients, it revealed new insights into how GBM developed and identified potential new targets for personalized treatment.
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Mammalian red blood cells are also involved in immunity: Toll-like receptor 9 binds CpG to promote inflammation and activate innate immunity
Time of Update: 2021-11-03
Red blood cells (RBC) occupies most of the circulating cells in mammals, and are mainly responsible for transporting oxygen to distant cell tissues and are an important part of aerobic respiration .
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Amec Lidocaine and Tetracaine Cream Obtained NMPA Clinical Trial Approval
Time of Update: 2021-11-03
On October 19, Amic issued an announcement stating that the application for the clinical trial of lidocaine and tetracaine cream filed on August 5, 2021 by its wholly-owned subsidiary, Beijing Nuobot Biotechnology Co.
, has been completed in October 2021.
