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The CRISPR system developed by GenKOre is recognized as a potential disruptor in the field of gene therapy
Time of Update: 2021-11-03
gene scissor technologyOnly by delivering the genetic load to the necessary location in the patient can efficient gene therapy be performed, and the best way to achieve this is to use adeno-associated virus (AAV) as a vector .
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Scientists have discovered how bacteria use liquid protein droplets to overcome stress
Time of Update: 2021-11-03
One of the main authors of the study, Professor Mark Lick of the Department of Physics and Biology of York University, said: "Our research shows that aggregates in bacteria are highly dynamic structures; they are what we call "organelles", but They lack a kind of membrane on the outside, and this kind of membrane is usually found in the organelles of more in-depth study, such as the nucleus of our own cells .
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Does eating nuts have health protection for breast cancer survivors?
Time of Update: 2021-11-03
A study on breast cancer survivors published in the International Journal of Cancer showed that eating nuts is associated with reducing the risk of breast cancer recurrence or death .
The 3449 breast cancer survivors in the Shanghai Breast Cancer Survival Study completed their dietary assessment 5 years after diagnosis.
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Science Sub-Journal: Evidence that Fetal Sex Affects Maternal Immunity
Time of Update: 2021-11-03
According to a new study published in the journal Science Translational Medicine , among pregnant women who tested positive for SARS-CoV-2 (the virus that causes COVID-19), the male placenta showed certain genes related to enhanced immune activation And protein levels are significantly higher than female placenta .
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Re-examination of Holliday junction: static and dynamic angle control
Time of Update: 2021-11-03
Scale bar: 100 nanometers The research results were jointly completed by the Wei Diming Molecular Design Group (MADlab) of the School of Life Sciences of Tsinghua University and the Seaman Group of New York University.
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Over 1.3 billion U.S. dollars to develop a new generation of bispecific antibody therapy Janssen reached cooperation
Time of Update: 2021-11-03
▲The Fcab platform can add 2 antigen binding sites in the Fc region of natural antibodies (picture source: F-star official website)mAb2 works through 3 mechanisms:1) Crosslinking: Bring together two different cells, or two receptors on the same cell, to activate the immune system .
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The origin of Nature’s horse is finally set
Time of Update: 2021-11-03
Farmers in north-central Kazakhstan are catching horsesPicture: Photo by Ludovic Orlando of the French Scientific Research Center The horse was first domesticated in the Ponte-Caspian steppe of the North Caucasus, and then conquered other parts of Eurasia within a few centuries .
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Most sunscreens are only one-fourth of the boasted SPF of UVA protection
Time of Update: 2021-11-03
Carla Burns, senior director of cosmetic science at EWG and one of the co-authors of the new study, said: "Most sunscreen products sold in the United States do not provide adequate protection against UVA and UVB .
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Researcher Lingling Chen was invited to publish a Preview article on circular RNA translation in Molecular Cell
Time of Update: 2021-11-03
TRS_Editor A{font-family:;font-size:12pt;}</> On October 21st, Researcher Chen Lingling from the Center for Excellence in Molecular Cell Science (Institute of Biochemistry and Cell Biology) of the Chinese Academy of Sciences was invited to publish an article entitled "Expanded regulation of circular RNA translation" in the international academic journal Molecular Cell.
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A gene was found in a high-fat diet that prevents excessive weight gain and diabetes
Time of Update: 2021-11-03
Researchers at the University of Tartu recently published a paper showing that the lack of a special protein, NEGR1, may lead to pre-diabetes in male mice.
The fact that Negr1 deficiency mainly affects male mice indicates that sex hormones play an important role in the development of diabetes .
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Scientists use primate stem cells to grow sperm cells
Time of Update: 2021-11-03
This study, recently published in the journal Fertility and Sterility Science, shows for the first time that primate embryonic stem cells can produce functional sperm cells in a petri dish .
Collaborators include Jon Hennebold of the National Primate Research Center of Oregon and Kyle Orwig and Gerald Schatten of the University of Pittsburgh .
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Cell Reports: Keep the balance of the brain
Time of Update: 2021-11-03
Image: A research team led by Lennart Mucke shows how reducing tau can prevent abnormal brain activity associated with Alzheimer's disease, autism, and epilepsy .
Mucke and his team found that reducing tau protein levels affects both excitatory and inhibitory cells, but in different ways .
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How bacteria can help solve the plastic pollution crisis
Time of Update: 2021-11-03
"Our research shows that the Ideonella sakaiensis bacteria can convert PET into poly(3-hydroxybutyrate) (PHB), a poly(hydroxyalkanoate) (PHA) plastic that is biodegradable," he continued .
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Porcine kidney is successfully used for human transplantation and has normal function in a short period of time
Time of Update: 2021-11-03
ArticleMedicine GuanlanAccording to the latest industry reports, the New York University Langone Medical Center team achieved a historic breakthrough: They transplanted a gene-edited pig kidney through a blood vessel in the thigh to a brain-dead volunteer .
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Class I new drug CS0159 was approved to enter clinical research
Time of Update: 2021-11-03
The Xu Huaqiang team of the Shanghai Institute of Medicine has conducted in-depth research on the mechanism of nuclear hormone receptor drugs for more than 20 years; Li Jia’s team has long been committed to the research and development of innovative drugs for metabolic diseases, focusing on metabolic diseases such as diabetes and non-alcoholic steatohepatitis.
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Nature Sub-Journal: Electric Liquid Drop
Time of Update: 2021-11-03
A group of physicists from HHU, Darmstadt University of Technology and the University of Gothenburg in Sweden have determined that this maxim is also correct in the field of physics, combining individual components to create something with completely new properties .
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The "sweet spot" of sleep: too little or too much sleep will cause cognitive decline
Time of Update: 2021-11-03
Over the years, researchers have tracked the cognitive function of a large number of elderly people and compared it with the measurement data of Alzheimer’s disease-related protein levels and brain activity during sleep.
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The University of Washington received $7.5 million to study elusive cell types in diseases such as aging and cancer
Time of Update: 2021-11-03
Louis is joining the National Institutes of Health (NIH) new research network focusing on the study of senescent cells, a rare and important cell that is difficult to study but vital to understand aging and aging diseases.
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Nature Methods technological breakthrough: Use sound to "observe" a single cell?
Time of Update: 2021-11-03
In their latest paper, the research team describes how the technology’s sensitivity can be increased to such an extent that it is now possible to image individual cells carrying acoustic reporter genes in human tissues .
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PNAS reveals the logic of the "second brain" of the body
Time of Update: 2021-11-03
"Neurons are the more common cell type and are mainly responsible for the electrical signals of the nervous system .
Gulbransen and his team have now demonstrated that glial cells play a more active role in the enteric nervous system .
