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Speed up the development of effective drugs for new coronary pneumonia
Time of Update: 2021-11-15
In the race against the virus, we need to speed up vaccination and build an immune barrier, and we also need to step up the development of effective drugs to make people feel more confident and safe in the face of this super infectious disease .
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In embryonic stem cells, scientists found that genes link pluripotency and apoptosis resistance
Time of Update: 2021-11-15
Researchers use genome-wide genetic screening to overexpress and inactivate ("knock out") thousands of genes that control the proliferation and differentiation of embryonic stem cells into the three germ layers .
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International team unites Chinese scientists to develop new virus "Google" map
Time of Update: 2021-11-15
David Cooper, a researcher in the Minor laboratory, said: “The most promising strain-independent antibody therapy developed for the treatment of COVID-19 uses this information to improve a method isolated from survivors who were infected with the SARS virus in 2003.
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How is the "multiple identities" of dopamine achieved in "Nature Neuroscience"?
Time of Update: 2021-11-15
Video: When the fruit flies received a drop of sucrose, the researchers recorded the activity of neurons in the brain's olfactory learning center .
Like humans, the dopamine neurons in fruit flies provide learning signals that help them associate specific odors with specific results .
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Guangzhou Health Institute proposes a model for phase separation to regulate the spatial order of mitochondrial genomes
Time of Update: 2021-11-15
The study found that the mitochondrial genome and its binding proteins used the most basic spontaneous aggregation of biomolecules to regulate the complex process of mitochondrial nucleoid assembly and transcription, and constructed the first model of phase separation to regulate the structure and function of the mitochondrial genome .
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Fujian Agriculture and Forestry University publishes a paper in Nature to reveal the important mechanism of auxin "acid hypothesis"
Time of Update: 2021-11-15
The research team of Fujian Agriculture and Forestry University-University of California Joint Center found that receptor-like kinase (TMK1) and multiple members of the proton pump family (H+-ATPase, AHAs) located on the cell membrane can specifically bind to protein profiles by immunoprecipitation.
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Gong Jiming's research group found that nitrate transporter mediates iron redistribution in plants
Time of Update: 2021-11-15
Further research found that these two genes both regulate low-affinity nitrate transport, and also significantly affect the nitrate distribution in plants, but the accumulation of nitrate and iron does not affect each other, indicating that NPF5.
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Nature Sub-Journal: The fatter women are, the more they have an advantage!
Time of Update: 2021-11-15
In mice (top) and humans (bottom), female adipose tissue (left) has a higher mitochondrial OXPHOS gene Second, it has been found in mice and humans that mitochondria in fat can predict metabolic syndrome .
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eLife: Turning off this gene can offset the genetic risk of Alzheimer's disease
Time of Update: 2021-11-15
When the researchers turned off the NHE6 gene and removed its protein from the cell, the primary endosome became more acidic, and this biochemical change seemed to prevent the accumulation of beta amyloid .
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Gene markers identify the drivers of resistance to treatment of metastatic breast cancer
Time of Update: 2021-11-15
A multi-institutional research team led by scientists at Baylor College of Medicine has discovered a genetic signature that can identify drivers of poor prognosis for advanced estrogen receptor-positive (ER+) breast cancer, which may be patients in the future Provide personalized treatment .
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Gong Jiming's research group reveals a new mechanism for reutilization of apoplast iron in plant roots (2021-06-23)
Time of Update: 2021-11-15
This paper reveals that Cdi gene-mediated cell wall synthesis plays an important role in the reutilization mechanism of apoplast Fe in plant roots .
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my country's first realization of the synthesis from carbon monoxide to protein
Time of Update: 2021-11-15
Researcher Dai Xiaofeng, director of the Feed Institute of the Chinese Academy of Agricultural Sciences, said that under artificial conditions, the use of naturally occurring carbon monoxide and nitrogen sources (ammonia) to biosynthesize protein on a large scale has long been considered by the international academic community to affect the development of human civilization and to life phenomena.
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4 commonly used drugs can reverse symptoms of Alzheimer's disease mouse model
Time of Update: 2021-11-15
Researchers have characterized the comprehensive characteristics of the mouse AD model in the early, middle and late stages at the phenotypic and molecular level, including transcriptomics and proteomics characteristics, and explored the molecular changes related to the onset, progression, and late stages of AD, and Correlate them with cognitive status and Aβ accumulation to study disease dynamics and compare observed changes with healthy aging processes .
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"First Evidence" Supports Research on Precision Treatment of Type 2 Diabetes Reveals Differences in Patients' Hypoglycemic Response
Time of Update: 2021-11-15
This crossover test called TriMaster evaluated 3 different types of commonly used drugs in second/third-line treatment, including DPP-4 (dipeptidyl peptidase-4) inhibitor sitagliptin, SGLT2 (sodium-glucose synergy) Transporter 2) Inhibitors canagliflozin and thiazolidinedione pioglitazone .
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Stem cell therapy for Alzheimer's disease shows positive potential
Time of Update: 2021-11-15
Recently, GABAeron announced positive preclinical research data obtained from Alzheimer's disease cell therapy based on induced pluripotent stem cells (iPSC) .
In this study, scientists first successfully induced human iPSCs carrying the APOE3 gene to differentiate into GABAergic interneuron progenitor cells.
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Prevent breast cancer like infectious diseases?
Time of Update: 2021-11-15
Recently, the Cleveland Clinic in the United States announced the launch of a unique phase 1 clinical trial that will evaluate the effect of a preventive cancer vaccine in preventing cancer recurrence in patients with early triple-negative breast cancer (TNBC) .
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Important pathogenic genes found in sudden cardiac death
Time of Update: 2021-11-15
Science and Technology Daily (Reporter Wu Chunxin, Correspondent Du Weiwei and Yang Cen) On October 25, the reporter learned from the People’s Hospital of Wuhan University that the latest issue of the
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Against the new crown mutation, "Science" releases a vaccine to strengthen the protection of primates
Time of Update: 2021-11-15
This preclinical study showed that six months after the macaque was vaccinated with the new crown vaccine mRNA-1273, the third dose of the mRNA vaccine can enhance the animal's antibody response, especially the neutralizing activity of the antibody against the mutant virus .
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Driven by innovation - Hollykangyuan fully automatic packaging solutions help the packaging industry to upgrade intelligently
Time of Update: 2021-11-15
Core technology accumulationIn order to promote the progress of the packaging industry in an all-round way, after years of scientific and technological innovation and core technology accumulation, Helixangyuan has realized accurate and stable drug dispensing, automatic adjustment of filling volume, touch terminal control, side film, rear discharge, and front opening in the field of automated packaging.
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Science Advances: Bacterial cells form membraneless organelles through liquid-liquid separation to enhance drug resistance
Time of Update: 2021-11-15
Screenshot of the paperPeking University Biomedical Frontier Innovation Center (BIOPIC), Beijing Future Gene Diagnosis Advanced Innovation Center (ICG), School of Life Sciences Researcher Bai Fan's research group once published in Molecular Cell in 2018 entitled "ATP-dependent dynamic protein" The research paper "aggregation regulates bacterial dormancy depth critical for antibiotic tolerance" reports a new type of intracellular structure in bacteria that can dynamically aggregate and disperse-protein precipitation aggregates (aggresomes) .
