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A mechanism may affect the infectivity of new coronavirus mutant strains
Time of Update: 2021-12-03
Scientists at the National Institutes of Health found that mutations in Alpha and Delta mutant strains overcome the activity inhibitory effect of an enzyme called GALNT1, which may enhance the ability of the virus to enter cells and increase the ability of the virus to spread .
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What can you eat to reduce the risk of heart disease in middle-aged?
Time of Update: 2021-12-03
Spinach cannot explain Popeye’s "superhuman power", but spinach and other iron-rich foods may have other effects in real life: reducing the risk of heart disease and premature death in middle age .
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Overcoming the shortcomings of oral Parkinson's disease therapy
Time of Update: 2021-12-03
The test results showed that compared with oral levodopa/carbidopa (levodopa/carbidopa), subcutaneous infusion of ABBV-951 for 24 hours a day significantly improved the fluctuation of motor symptoms in patients with advanced Parkinson's disease .
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There is a difference in the time of taking the same hypoglycemic drugs
Time of Update: 2021-12-03
It turned out that Master Wang was taking a hypoglycemic drug called "Uglucose", which should be taken 30 minutes before meals .
Some diabetics also take two or more hypoglycemic drugs, which need to be taken at different times, and feel more troublesome, so they take them together .
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Gene therapy targeting neurons in the substantia nigra is expected to improve the efficacy of levodopa in the treatment of Parkinson's disease
Time of Update: 2021-12-03
In the advanced stages of Parkinson's disease, the drug levodopa becomes less effective in treating symptoms due to the unstoppable loss of dopamine-releasing neurons .
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Can lipid-lowering drugs and vitamins also treat Alzheimer's disease?
Time of Update: 2021-12-03
Recently, a study published in Science Signaling, a sub-Journal of "Science", shows that the combination of two "old drugs" that have been on the market for decades not only significantly reduces the beta amyloid associated with Alzheimer's disease in animal models.
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Dialysis treatment takes an important step towards precision medicine
Time of Update: 2021-12-03
Science and Technology Daily, Berlin, November 2 (Reporter Li Shan) Recently, an international research team led by scientists from the University of Zurich found that a common gene mutation of aquaporin-1 (AQP1) reduces the number of water channels in the cell membrane, and thus Increase the risk of death in patients receiving peritoneal dialysis due to renal failure .
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This neural circuit identified by scientists will make you "shocked" by stimulation
Time of Update: 2021-12-03
The reporter learned from the University of Science and Technology of China on November 8 that the research team of Professor Xiong Wei from the Department of Life Sciences and Medicine and the First Affiliated Hospital of the school revealed the cochlear nucleus-pontine caudal reticular nucleus-spinal cord motor neurons.
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How to treat fatty liver?
Time of Update: 2021-12-03
SAB gene activation and increased protein levels are related to liver disease progression in mice and human fatty liver .
But Neil Kaprowitz, a professor of medicine at the Keck Medical Center, said that even after being fed a high-fat, high-sugar diet for one year, the liver of mice has already developed inflammation and fibrosis.
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Why is the most dangerous breast cancer difficult to treat?
Time of Update: 2021-12-03
In a new study published in Nature, a joint team found a key clue: A molecule called DDR1 erects a fortification around the tumor to prevent immune cells from attacking and killing tumor cells .
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Targeting antibodies can "break the prevention" of breast tumors
Time of Update: 2021-12-03
Science and Technology Daily, Beijing, November 4 (Reporter Zhang Mengran) American researchers have discovered a key molecule in certain types of breast cancer that can prevent immune cells from entering the tumor to kill the cancer cells inside .
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It is expected to control hypertension with one shot in half a year!
Time of Update: 2021-12-03
On November 8, 2021, Alnylam Pharmaceuticals announced the initiation of a global phase 2 clinical trial to evaluate RNAi therapy zilebesiran (formerly ALN-AGT) in hypertensive patients whose blood pressure cannot be adequately controlled by standard antihypertensive drug therapy.
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These "hard technologies" are indispensable for blocking the "chain of transmission" of the new coronavirus
Time of Update: 2021-12-03
What measures has the city taken to stop the spread of the new crown virus as quickly as possible?Make nucleic acid screening information run faster and more punctuallyAfter the outbreak, the city’s epidemic prevention and control headquarters responded quickly, acted overnight, and handled decisively.
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New liquid biopsy technology: a urine test to predict the risk of cancer progression within 5 years
Time of Update: 2021-12-03
After their comparison, they found that when the patient was classified as PUR 4 risk by urine test, a large number of grade 4 cancer cells would appear in samples still at Gleason 2-3 level.
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Johnson & Johnson's Ebola vaccine program safely induces strong immune responses in healthy and HIV adults
Time of Update: 2021-12-03
Recently, data from a study published in the journal PLOS Medicine in the United States showed that Johnson & Johnson (JNJ)'s Ebola vaccine program (2-dose immunization)-Zabdeno® (Ad26.
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Preliminary clinical results of innovative TCR immunotherapy combination for treating melanoma are positive
Time of Update: 2021-12-03
Recently, Immunocore announced that it will demonstrate its T-cell receptor therapy tebentafusp combined with PD-L1 inhibitor durvalumab and/or CTLA4 inhibitor tremelimumab at the 36th annual meeting of the Society for Cancer Immunotherapy (SITC) in the treatment of metastatic skin melanoma (MCM) Phase 1b clinical trial results .
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How to resist cognitive decline in the brain? Research discovers new treatment targets
Time of Update: 2021-12-03
In mice living in a rich environment, the activity of this transcription factor in neurons is particularly high; and in patients with Alzheimer's disease whose cognitive function remains normal, many downstream genes regulated by MEF2 show enhanced expression, and The transcriptional activity of MEF2 can strongly predict the end-stage cognitive performance of patients .
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Accelerate the development of gene therapy FDA/NIH leads the establishment of a research and development alliance
Time of Update: 2021-12-03
A few days ago, the US FDA announced that the FDA, the National Institutes of Health (NIH), 10 biopharmaceutical companies and 5 non-profit organizations have reached a partnership to jointly accelerate the development of gene therapies and treat patients with rare diseases .
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Robust Medical will exhibit innovations in wound care and infection protection at MEDICA 2021
Time of Update: 2021-12-03
We continue to promote innovation, and constantly explore the use of environmentally friendly and sustainable raw materials to create a new generation of wound healing and infection prevention products, and minimize the impact on the climate and the environment.
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AbbVie's oral JAK1 inhibitor Rinvoq in the treatment of moderate to severe RA shows long-term sustained response
Time of Update: 2021-12-03
AbbVie recently announced the evaluation of an oral JAK1 inhibitor Rinvoq (upadacitinib, upatinib, 15 mg, once daily) for the treatment of patients with rheumatoid arthritis (RA) in the Phase 3 SELECT-BEYOND clinical trial of a post-mortem analysis New data .
