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Hippo signaling does not direct normal organ growth
Time of Update: 2023-01-06
According to a new study, the Hippo signaling pathway — a genetic program thought to play a central role in organ development — does not direct normal organ growth in fruit flies and mice.
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PNAS: Down syndrome, like Alzheimer's, is a biprion disease
Time of Update: 2023-01-06
essayAβ and tau prions feature in the neuropathogenesis of Down syndrome People with Down syndrome develop neurodegenerative tangles and plaques associated with Alzheimer's in their brains and often show signs of neurodegenerative diseases at the age of forty and fifty.
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The sense of smell affects the causes of obesity
Time of Update: 2023-01-06
From there, the scientists used the same two groups of mice to see how the smell of food or the visual stimuli of food affected the distribution of body fat during fasting.
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A novel adamantane-type PPAP pain relief molecule with significant Cav3.2 T-type calcium channel inhibition
Time of Update: 2023-01-06
8;font-family:;font-size:12pt;}Polycyclic polyprenylated acylphloroglucinol (PPAP) is a class of natural products with heterozygotic pathways, mainly including bridge ring type, adamantane type and further cracking ring due to the above two architecture types, Rearrangement and sidechain looping of its precursors results in a variety of structurally diverse derivative structure types.
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MINQI WANG'S LAB PUBLISHED PAPERS IN FERMENTATION-BASEL
Time of Update: 2023-01-06
3390/fermentation8100531Published: OCT 2022Document type: ArticleAttachment: Full text link ：Production of Butyric Acid from Hydrolysate of Rice Husk Treated by Alkali and Enzymes in Immobilized Fermentation by Clostridium tyrobutyricum Ct Delta pta（ IF=5.
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The molecular enzymatics research team of Shanghai Jiaotong University developed an unnatural substrate binding adaptation strategy to achieve efficient evolution of aminotransferases
Time of Update: 2023-01-06
Recently, the internationally renowned journal ACS Catalysis published the research results of Cui Li, an associate researcher of Professor Feng Yan's team of Shanghai Jiaotong University, "Molecular
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A new method of delivering drugs to malignant brain tumors
Time of Update: 2023-01-06
In a new study, researchers show how a modified peptide helps an anti-cancer drug cross the blood-brain barrier in mice.
In a new study, researchers show how a modified peptide helps an anti-cancer drug cross the blood-brain barrier in mice.
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A new method of delivering drugs to malignant brain tumors
Time of Update: 2023-01-06
In a new study, researchers show how a modified peptide helps an anti-cancer drug cross the blood-brain barrier in mice.
In a new study, researchers show how a modified peptide helps an anti-cancer drug cross the blood-brain barrier in mice.
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Guangzhou Health Center has made progress in the research of antibody immune response in the new coronavirus escaping population
Time of Update: 2023-01-06
The study found a human neutralizing antibody R1-32 that targets the viral protein receptor binding domain (RBD) semi-hidden epitope and has a high affinity, mainly Prevents the virus from entering the cell by breaking open the spike protein and disintegrating it; Analysis of the antibody panel library showed that R1-32-like antibodies encoded by IGHV1-69 were widely induced in people infected with the new crown.
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Nature Zhang Ning/Zhang Zemin/Zhu Jiye collaborated to reveal liver cancer immune microenvironment subtypes and neutrophil heterogeneity
Time of Update: 2023-01-06
The heterogeneity of the immune microenvironment is one of the important reasons for tumor resistance, recurrence and poor prognosis. In recent years, immunotherapy and combination therapy have broug
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Academician Park Shilong's team wrote an article in Nature Earth Science showing that greening vegetation is beneficial to global surface water resources through cross-regional water vapor transport
Time of Update: 2023-01-06
Pattern of integrated hydrological effects of global vegetation (+ indicates significantly advantageous, O indicates insignificant, in the legend on the left, ?) indicates significant disadvantage; The left and right symbols indicate the impact on local/regional and downwind surface water availability, respectively)The research team further focused on the cross-regional impact of the current large-scale afforestation projects around the world, and developed the first global comprehensive hydrological pattern of afforestation (Figure 1).
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Journal of Cell Biology I The team of Professor Xuebiao Yao of the University of Science and Technology of China discovered a new mechanism of polar growth regulation of asymmetric cell division
Time of Update: 2023-01-06
, 2020J Biol ChemJ Biol Chem In view of the biological significance of GAP protein of Cdc42 in the process of cell polarity formation, the research team first established a model system for using fission yeast spores to study asymmetric cell division.
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Chinese scholars and overseas collaborators have made progress in the study of the tectonic pattern of the New Archean plate
Time of Update: 2023-01-06
Fig. 1 Phase equilibrium-trace element simulation reveals geothermal gradients in subduction zones (left) and tectonic patterns (right) Fig. 2 Conceptual model of plate tectonic process at the Archea
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Cell subissue: How did the brains of squid and octopuses come about
Time of Update: 2023-01-06
This suggests that although vertebrates and cephalopods began to differentiate 500 million years ago, not only did they use similar mechanisms to make their large brains, but that this process and the way cells move, divide, and form may have fundamentally mapped out the blueprints needed to develop such nervous systems.
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Tomson By-Health Collagen Chondroitin Calcium Tablets care for the joint health of the elderly
Time of Update: 2023-01-06
In addition to daily improvement of diet and exercise, many careful children will prepare some dietary supplements such as Tomson By-Health Collagen Chondroitin Calcium Tablets for their parents, why is it?
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Tang Hongzhi's research group of Shanghai Jiaotong University reviewed the theory of microbiome engineering and its application and prospect in the field of environment
Time of Update: 2023-01-06
The collaborative review "Guided by the principles of microbiome engineering: Accomplishments and perspectives for environmental use" by Professor Tang Hongzhi of Shanghai Jiao Tong University and Associate Professor Nie Yong of Peking University was officially launched on mLife on November 3, 2022 。 This review was jointly completed by young scholars from Shanghai Jiao Tong University, Peking University and ETH Zurich, and supported by Professor Wu Xiaolei of Peking University.
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Nature's dominoes of hormones
Time of Update: 2023-01-06
At the same time, during directed mutagenesis, we change the structure of the protein, which means that we exclude three functional amino acids in one sequence or in one group, which completely takes away the activity of the studied adenylate cyclase.
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DNA barcoding reveals the ability of cancer cells to evade immune system defenses
Time of Update: 2023-01-06
According to a new scientific study from the Gavin Institute for Medical Research, some cancer cells can use parallel mechanisms to circumvent the immune system's defenses and resist immunotherapy treatments.
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Wang Hongwei and his collaborators jointly developed a new functional graphene for improving the advantage orientation of cryo-EM
Time of Update: 2023-01-06
In response to these problems, Wang Hongwei's research group, Rao Liao's research group and Peking University Peng Hailin's group jointly developed a new functional graphene electron microscope carrier network, which can help solve the problems of sample particle advantage orientation and gas-liquid interface.
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The latest paper from Xiamen University: A new mechanism of adaptive thermogenesis mediated by beige adipose tissue under long-term cold stimulation
Time of Update: 2023-01-06
Paper link: class="vsbcontent_end" _msthash="101744" _msttexthash="978393">(Photo/text Li Boan's research group) Adaptive thermogenesis is a metabolic thermogenic mechanism of the body to external stimuli, which plays an important role in regulating energy homeostasis and is essential for maintaining body temperature and promoting the survival of animals in cold environments.
