-
The second-generation new crown vaccine is here!
Time of Update: 2022-01-08
On December 27, the UAE Ministry of Health and Prevention approved the emergency use license for the second-generation recombinant protein COVID-19 vaccine of Sinopharm Group China Biotech .
-
Chinese scholars have made new progress in the research field of circular RNA regulation of vascular remodeling and protection
Time of Update: 2022-01-08
The phenotypic transformation of vascular smooth muscle cells (VSMC) is the pathophysiological basis for the occurrence and development of major cardiovascular and cerebrovascular diseases such as coronary heart disease, stroke, and hypertension.
The research team screened highly expressing circular RNA-circEsyt2 from a variety of VSMC phenotypic transformation disease mouse models.
-
PNAS: Alzheimer's disease risk genes interfere with the protective mechanism of the brain
Time of Update: 2022-01-08
In this study, “the formation of glial lipid droplets induced by neuron ros was altered by the loss of Alzheimer’s disease-related genes,” an article published in the Proceedings of the National Academy of Sciences (PNAS) also revealed The evidence supports reactive oxygen species (ROS), which is a natural by-product of cell metabolism, is related to inflammation and other processes, and is a key factor leading to the destruction of neuroprotective mechanisms .
-
Fallopian tube organoids show how BRCA1 mutant women with ovarian cancer start
Time of Update: 2022-01-08
Stem cell scientists at Cedars-Sinai Medical Center have revealed the origin of a common ovarian cancer by establishing a fallopian tube tissue model .
-
Sub-Journal of "Nature": Miniature Drug Factory——CAR-T Cells
Time of Update: 2022-01-08
"This anti-cancer molecule was discovered by Derek Tan, chairman of the SKI Chemical Biology Project, when he was developing antibiotics, and he was Dr.
But getting CAR-T cells to produce a small molecule anti-cancer drug is a tricky prospect .
-
Neuroprotective mechanism of Alzheimer's disease dangerous gene changes
Time of Update: 2022-01-08
This model allows them to observe the effects of knocking out specific genes in neurons or glial cells on lipid droplet formation and neurodegeneration with or without ROS .
-
The Ren Qiushi team of the Future Institute of Technology proposes a new multimodal functional imaging technology for non-invasive screening of major chronic diseases
Time of Update: 2022-01-08
Words for Java 18. 9" >The human brain obtains more than 80% of external information through the eyes, so eye health is very important to ensure people's quality of life . At the same time, the huma
-
Can eating walnuts make people smarter?
Time of Update: 2022-01-08
"Our results show that adding choline to the standard prenatal vitamin regimen is beneficial for all people," said Barbara Strupp, a professor in the Department of Nutritional Science (DNS) and Psychology , "Prenatal choline supplementation improves children's sustained attention: a 7-year follow-up of a randomized controlled feeding trial", published in the "Journal of the Federation of American Societies for Experimental Biology" on December 28 .
-
South China Botanical Garden reveals that chloroplast genome trees optimize the cognition of community construction in large forest plots in my country
Time of Update: 2022-01-08
A first-generation DNA barcode fragment ( matK + rbcL + trnH-psbA ) and 79 protein-coding genes of the chloroplast genome constructed a community phylogenetic tree, and compared the effects of different tree-building methods on the calculation results of phylogenetic diversity index and functional trait phylogenetic signals .
-
Nature Aging: Naked mole rats reveal their age through epigenetics
Time of Update: 2022-01-08
They say that using epigenetic clocks can not only estimate the age of wild naked mole rats, but also help study their potential as model organisms for aging, longevity, and disease suppression .
-
Science Sub-Journal: Why exercise can prevent insulin resistance?
Time of Update: 2022-01-08
"He said: "Using compounds to activate the NOX4 synergistic adaptation mechanism may improve key aspects of aging, including the development of insulin resistance and type 2 diabetes .
-
Depression, blood markers of antidepressant response are confirmed
Time of Update: 2022-01-08
Researchers led by Mark Rasenick, a well-known professor of physiology and biophysics and psychiatry at the University of Illinois at Chicago, published a new proof-of-concept study that discovered a biomarker in human platelets that can be used to track the degree of depression .
-
The Li Faxin research group of the School of Engineering developed the world's first hard material DMA-dynamic thermomechanical analyzer
Time of Update: 2022-01-08
Figure 1 Hard material DMA based on electromechanical impedance method and its automatic measurement software interfaceModulus and internal friction (or damping) is the basic physical properties of all solid material, which can change with temperature accurately reflects the evolution of the interior of the material, such as atomic diffusion, grain boundary sliding, solid state phase transition .
-
Recombination of CAR-T cells in Nature's sub-publication, discovering a "mini pharmacy" for cancer drugs
Time of Update: 2022-01-08
In order to overcome these obstacles, a team of ski researchers designed a brand-new car T cell as a "micropharmacy": it can provide a toxic drug to directly load tumors, killing tumor cells contains cancer markers and nearby tumor cells.
-
Will the next breakthrough in diabetes treatment be "it"?
Time of Update: 2022-01-08
In the coming decades, the dual prevalence of type 2 diabetes (T2DM) and obesity will continue to be a major global health challenge . For patients with T2DM and obesity, because life> . Recently, "
-
Science: Invasive species can be found through airborne DNA from plants
Time of Update: 2022-01-08
"The DNA in the air may change our ability to monitor and study biodiversity," said Kristine Bohmann, a molecular ecologist at the University of Copenhagen, who was not involved in the work .
-
A small maneuver space may be the key to effective peptides for the treatment of diabetes
Time of Update: 2022-01-08
New research shows that peptides (short pieces of protein) used to treat type 2 diabetes may be more effective if they can move flexibly back and forth between different shapes .
-
"Cryogenic bioprinting" can provide a large number of frozen cells
Time of Update: 2022-01-08
Researchers from the Zhang laboratory at Brigham and Women’s Hospital have developed a technology they call “low-temperature bioprinting,” which uses bio-ink embedded in cells to print frozen, complex structures that can be easily Store it up for later use .
-
High resolution showing how cells "eat"
Time of Update: 2022-01-08
Kural said: "It is important to understand the origin and dynamics of membrane-bound vesicles-they can be used for drug delivery, but they can also be hijacked by viruses and other pathogens to enter and infect cells .
-
【Document Express】Nature Communications explores the mystery of zygotic genes
Time of Update: 2022-01-08
First, the author analyzed the zygotic transcripts in the ZGA period through GRO-seq and found 6249 key genes, and 5680 of them do not depend on Zelda for activation transcription; confirmed by ChIP-seq, ATAC-SEQ, MNase-seq The transcription initiation sites of these genes are abundantly enriched in H2A.
