-
"The Lancet" single-dose Chinese Ad5-NCOV COVID-19 vaccine is safe and effective in Phase III clinical trials
Time of Update: 2022-01-10
"Our research shows that a single dose of Ad5-nCoV is very effective for serious diseases and may help relieve the tremendous pressure COVID-19 has placed on health systems around the world, because it can prevent people from getting serious illnesses or needing to be hospitalized .
-
The way to improve eye health is through the intestines?
Time of Update: 2022-01-10
After completing the National Institutes of Health (NIH) "Clinical Scientist Research Guidance Career Development Award", Lin became the first recipient of the Ohio State University School of Medicine "Physician-Scientist Transitional Support Award" .
-
He Fang's laboratory published a paper in JOURNAL OF VIROLOGY
Time of Update: 2022-01-10
078 )Authors: Zheng, Suya ; Gu, Han ; Han, Guangwei ; Xu, Huiling ; Liu, Zehui ; Lu, Ying ; He, Fang* ()Source publication: JOURNAL OF VIROLOGYVolume 95, Issue 22, Literature Number e01119-21DOI10.
1128/JVI.
-
Li Xiaoliang's laboratory published a paper in JOURNAL OF VIROLOGY
Time of Update: 2022-01-10
078 )Authors: Xu, Jidong ; Mao, Junyong ; Han, Xiao ; Shi, Fushan ; Gao, Qin ; Wang, Tingjun ; Zhang, Zhenning ; Shan, Ying ; Fang, Weihuan ; Li, Xiaoliang* ()Source publication: JOURNAL OF VIROLOGYVolume 95, Issue 18, Literature Number e00853-21DOI10.
-
Nature's new achievement solves ten-year mystery and analyzes the structure of key proteins in Parkinson's disease
Time of Update: 2022-01-10
Zhong Yan Gan said: “An important discovery of ours is that PINK1 forms a dimer, which is essential for initiating or activating proteins to perform their functions .
-
Effective mixed backbone antisense oligonucleotides inhibit the expression of mutant C9orf72
Time of Update: 2022-01-10
Using C9-ALS/FTD patient-derived cells and C9ORF72 BAC transgenic mice, we generated and optimized antisense oligonucleotides (ASOs), which can selectively attenuate the expression of G4C2 repeat transcripts and effectively Inhibit the level of poly (GP) dipeptide in the tissue .
-
The Kunming Institute of Botany and a number of units took loquat as an example to reveal that the tropical and subtropical transition areas are hot spots for paleohybridization
Time of Update: 2022-01-10
The study collected a total of 47 populations of 23 species of loquat in China and Southeast Asia (Figure 2 ), a total of 817 individuals (including 12 species and 19 populations of the Yunnan-Guizhou Plateau ), and selected 3 chloroplast fragments and 5 nuclear gene fragments Group sequencing was carried out.
-
Nature Sub-Journal: Monitoring bacterial strains, not just species
Time of Update: 2022-01-10
Katie Pollard of the Gladstone Institute has published two new research reports showing that monitoring bacterial strains, not just species, can better understand the microbiome .
-
Shao Qingjun's laboratory published a paper in ANIMALS
Time of Update: 2022-01-10
Title: Experimental Studies on the Impact of the Projected Ocean Acidification on Fish Survival, Health, Growth, and Meat Quality; Black Sea Bream (Acanthopagrus schlegelii), Physiological and Histological Studies ( IF=2.
3390/ani11113119Publication time NOV 2021Document Type ArticleAttachment: Full text link
-
Professor Jianqing Xu’s team and collaborators reported that the combination of Lactobacillus plantarum strain and the new crown vaccine can significantly improve and maintain the immune response against the new crown after vaccination
Time of Update: 2022-01-10
<> </> Vaccination of the new coronavirus (SARS-CoV-2) vaccine is a key means to prevent and block the spread of the new coronavirus . Numerous studies at home and abroad have shown that the serum a
-
Mitochondrial C5aR1 activity in macrophages controls IL-1β production in aseptic inflammation
Time of Update: 2022-01-10
It is proved that the complement protein C5a sends a signal on the mitochondrial membrane through its receptor C5aR1 to control the production of IL-1β in response to the uptake of cholesterol crystals (CC) .
-
Science: High-fiber diet can improve immunotherapy for patients with melanoma
Time of Update: 2022-01-10
According to a latest large-scale international collaborative study, when patients with melanoma receive immunotherapy, if their diet is rich in fiber, their immune system is more likely to kill cancer cells and produce a better response to the therapy .
-
Neuron discovers key neural mechanisms that support advanced cognitive abilities
Time of Update: 2022-01-10
The research team found that when the brain uses these strategies to organize information, the neural code in the prefrontal cortex is less dependent on the highly selective responses of individual neurons .
-
Chen Lingling's group discovered the immunogenic mechanism and potential applications of in vitro synthesis of circular RNA
Time of Update: 2022-01-10
Through in-depth comparison and analysis of the characteristics of different methods of in vitro synthesis of circular RNA, the study clarified the immunogenicity of in vitro synthesis of circular RNA and the molecular mechanism, and found that circular RNA with no immunogenicity and double-stranded structure can effectively inhibit natural immunity The activation of factor PKR reveals the application potential of in vitro synthesized circular RNA for the treatment of autoimmune diseases related to abnormal activation of PKR .
-
In experimental models, CBD can reduce the size of glioblastoma and support the environment
Time of Update: 2022-01-10
They found that CBD seems to be good at changing the tumor’s ecosystem or supporting the tumor’s microenvironment, including restoring inflammation levels, rather than protecting glioblastoma, which may make it a safe, effective and novel adjuvant treatment for these patients .
-
Nature: No more flu shots every year?
Time of Update: 2022-01-10
Researchers have designed a more versatile experimental flu vaccine that stimulates the body to produce antibodies against HA's hard-to-change stem, which stretches like a stem between the influenza virus particles and the HA head .
-
Controlling the burning of the natural environment helps offset our carbon emissions
Time of Update: 2022-01-10
But we have found that in ecosystems including temperate forests, prairies, and grasslands, fires can stabilize or even increase soil carbon," Dr.
"Fires will burn the plant matter and organic layers in the soil, and in severe wildfires, this will cause carbon erosion and leaching .
-
Crop disease green prevention and control research team reveals new functions of pathogenic fungi early secretion pathway
Time of Update: 2022-01-10
SsEmp24-SsErv25 interaction regulates the early secretion pathway of Sclerotinia sclerotiorum and affects its growth and pathogenesisIn their research, scholars from our school revealed that the p24 family protein Emp24-Erv25 complex in filamentous fungi recruits cargo proteins into vesicles and participates in the early secretory pathway through vesicle transport .
-
Sun Baolin's research group from the University of Science and Technology of China revealed that the LcpB protein regulates the cell wall synthesis and virulence of MRSA strains...
Time of Update: 2022-01-10
aureus infection mechanism, relevant research results " LcpB IS A Pyrophosphatase Responsible for Wall teichoic acid Synthesis and virulence in Staphylococcus aureus Clinical "Isolate ST59" was published in the magazine " Frontiers in Microbiology " .
-
Nature Methods: A new technology that can perform detailed genetic analysis on resting human immune cells
Time of Update: 2022-01-10
Keppler of the LMU Max von Pettenkofer Institute have now developed a method that allows these specific immune cells to be genetically manipulated in an efficient and simple manner under physiological conditions for the first time .
