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Animal protein plays a key role in the development of childhood blood cancer
Time of Update: 2022-01-10
A new study shows that the amino acid valine, a molecular component of many animal proteins, plays a key role in the cancerous growth of T-cell acute lymphoblastic leukemia .
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Xu Shuhua’s team analyzes the genetic origin and phenotypic convergence evolution mechanism of Asian tropical natives
Time of Update: 2022-01-10
According to the population distribution rules of the early Asian ancestors, the researchers identified the gene fragments representing the components from the existing Asian tropical indigenous genomes without using any ancient DNA , and foundIt may be closely related to the adaptive evolution of human hair morphology (such as LIMS1 gene) and bone development (such as COL24A1 gene) .
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The first model to predict the lifetime risk of heart failure
Time of Update: 2022-01-10
Now, the model will allow doctors for the first time to estimate a person’s risk of heart failure in the next 30 years based on a person’s current level of risk factors, such as body mass index, blood pressure, cholesterol, diabetes, and smoking status .
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A large-scale bacterial sequencing method for only $10 per genome
Time of Update: 2022-01-10
A global consortium of scientists led by the Earlham Institute and the University of Liverpool has developed an efficient, inexpensive method for large-scale bacterial genome sequencing that can enable researchers in low- and middle-income countries (LMICs) An inexpensive and available method of sequencing bacterial pathogens—each genome costs less than $10 .
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Anti-aging new recruits scientists design "smart bombs" to remove old cells
Time of Update: 2022-01-10
Recently, Spanish and British researchers have collaborated to design a "smart bomb" antibody-conjugated drug (ADC), which can slow down aging by removing senescent cells from human tissues .
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Peng Jinrong's laboratory published a paper in NUCLEIC ACIDS RESEARCH
Time of Update: 2022-01-10
Title: Rcl1 depletion impairs 18S pre-rRNA processing at the A(1)-site and up-regulates a cohort of ribosome biogenesis genes in zebrafish ( IF=15.
542 )Authors : Zhu, Qinfang; Tao, Boxiang; Chen, Hong; Shi, Hui; Huang, Ling; Chen, Jun; Hu, Minjie; Lo, Li Jan; Peng, Jinrong* ()Source publication: NUCLEIC ACIDS RESEARCHVolume : 49 Issue : 10 Page : 5743-5759DOI: 10.
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Why is it healthy for them to eat sugar?
Time of Update: 2022-01-10
The results showed that people with this genetic variant suffer from sucrase-isomaltase deficiency, which means that they have a special way of metabolizing sugar in the intestine .
One group was artificially inhibited to absorb sugar, which is similar to the genetic variation found in Greenlanders .
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Wang Chengshu's research group reveals the regulatory mechanism and function of insect fungal synthesis of 2-pyridone
Time of Update: 2022-01-10
On December 14, 2021, the international academic journal mBio published online a research paper entitled "Inductive production of the iron-chelating 2-pyridones benefits the producing fungus to compete for diverse niches" by Wang Chengshu's research group .
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Latest study: Inhibition of kinase GCN2 improves liver lipid deposition in obese mice
Time of Update: 2022-01-10
2021 Nian 12 Yue 23 days, College of Life magazine Lu Zhongbing research group in the field of oxidative stress and free radicals authority Redox Biology Online published an article Title ldquo &; Inhibition of hepatic steatosis and GCN2 alleviates oxidative Stress in the MICE Obese: Involvement of NRF2 The research paper of regulation ” reveals the molecular mechanism of inhibiting the kinase GCN2 to improve liver lipid deposition and oxidative stress in obese mice .
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Associate Professor Xiao Yuling and Professor Hong Xuechuan's research group have made new progress in long-circulation tumor imaging and surgical navigation resection
Time of Update: 2022-01-10
Recently, the well-known journal of medicinal chemistry under the American Chemical Society, " Journal of Medicinal Chemistry " ( Journal of Medicinal Chemistry ) published an online publication of the team of Associate Professor Xiao Yuling and Professor Hong Xuechuan of our school in the near infrared second zone ( NIR-II , 1000-1700 nm ) The latest research results in the design of molecular long circulating tumor imaging fluorophores and surgical navigation resection .
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"Nature" How do our organs know when to stop growing?
Time of Update: 2022-01-10
In previous studies, Marcos Gonzalez-Gaitan's research team and the German research team have shown that these concentration gradients of DPP extend to larger or smaller areas depending on the size of the developing tissue .
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Child obesity is linked to mothers’ unhealthy diet during pregnancy
Time of Update: 2022-01-10
A new study led by the University of Southampton shows that supporting women to eat a healthy diet before pregnancy can reduce the risk of obesity in their children .
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Cell: What makes mRNA vaccines effective against SARS-CoV-2
Time of Update: 2022-01-10
"The longer the T follicle helper cells provide help, the better the antibody, and the more likely you are to have a good memory response," said Philip Mudd, MD, assistant professor of emergency medicine at the University of Washington and co-corresponding author.
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How "photosynthetic" algae survived long periods of darkness
Time of Update: 2022-01-10
This study discovered how some single-celled algae species survived the last mass extinction, and this discovery may change our understanding of global ocean processes .
In a new study, scientists from the Bigelow Laboratory for Ocean Sciences discovered how some species of single-celled algae survived the mass extinction.
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Li Weifen laboratory issued...
Time of Update: 2022-01-10
132 )Authors: Zhou, Yuanhao ; Wang, Baikui ; Wang, Qi ; Tang, Li ; Zou, Peng ; Zeng, Zihan ; Zhang, Huihua ; Gong, Li ; Li, Weifen ()Source publication: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESVolume 22 Issue 22 Literature Number 12388DOI10.
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Xu Jianqing's team and collaborator "Nature Immunology" reveal a new mechanism for virus-specific CD4+ T cell immune memory maintenance
Time of Update: 2022-01-10
A research paper by preventing ferroptosis , this paper reports a new mechanism by which mTORC2 signaling inhibits iron death and promotes the long-term maintenance of memory CD4 T cells .
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Neuron: a new GRAB fluorescent probe used to detect the spatiotemporal dynamic changes of extracellular ATP
Time of Update: 2022-01-10
On December 22, 2021, Peking University’s Li Yulong Laboratory published a research paper titled A sensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo in Neuron magazine, reporting on the new gene-encoded ATP probe GRABATP1.
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"Cell Stem Cell" changes scientific dogma
Time of Update: 2022-01-10
It is well known that in human embryos, the initiation of transcription (embryonic genome activation) occurs at the eight-cell stage .
Now, a research team in the United Kingdom has thoroughly studied gene expression in single-cell embryos, and their findings indicate that gene expression begins at the single-cell stage of human embryos .
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The Li Yulong laboratory of the School of Life Sciences developed a new GRAB fluorescent probe for detecting the spatiotemporal dynamic changes of extracellular ATP
Time of Update: 2022-01-10
On December 22, 2021, Peking University’s Li Yulong Laboratory published an online research paper entitled " A sensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo " in Neuron magazine , reporting a new gene-encoded ATP probe GRAB ATP1 .
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Studies have found that prebiotic supplements can help women reduce sugar intake by 4%
Time of Update: 2022-01-10
A new study from the University of Surrey found that young women taking prebiotic supplements for four weeks choose healthier foods and consume less sugar .
