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Qian Lichun's laboratory published a paper in ITALIAN JOURNAL OF ANIMAL SCIENCE
Time of Update: 2022-01-10
Title: Effects of dietary phytosterols supplementation on serum parameters, nutrient digestibility and digestive enzyme of white feather broilers ( IF=2. 376 )Authors: Yuan, Chunchun ; Ding, Xiaoqing
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Researcher Fei Li's team from the Center for Frontier Science of Molecular Networks of Diseases published a research paper on Microbiome, revealing that intestinal flora plays an important role in improving testicular damage
Time of Update: 2022-01-10
Recently, Li Fei's research team from the Frontier Science Center of Disease Molecular Networks of our hospital published online research results "Polyamine metabolism links gut microbiota and testicular dysfunction" in the journal Microbiome (IF=14.
The project's research found that drug-induced testicular damage can disrupt the dynamic balance of intestinal flora and reduce testicular polyamine levels.
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Precise positioning of genes contributes to the correct positioning of the human heart
Time of Update: 2022-01-10
Developmental biologists have long known that the eccentric position of the heart and other organs is related to a group of cells called the left and right organisers, which are formed briefly in the early embryo .
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The first use of CRISPR-Cas9 combined with plant bacteria to transform pathogenic fungi
Time of Update: 2022-01-10
Teresa O'Meara, Assistant Professor of Microbiology and Immunology at the University of Michigan School of Medicine, said: “Almost all fungal pathogens, from valley fever to yeast infections, have morphological changes and seem to combine toxic processes with changes in form .
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"Shengli Oilfield" discovered archaea that can convert oil into purer energy
Time of Update: 2022-01-10
Now, researchers have successfully cultivated an ancient organism called "methanobacterium" from the sedimentation tank of an oil production facility, which can handle this complex reaction on its own .
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"Nature": The latest research on Omicron's immune escape (Tengshengbo Pharmaceutical's BRII-198 maintains significant activity)
Time of Update: 2022-01-10
A new study by Columbia University researchers in collaboration with scientists from the University of Hong Kong adds more evidence that Omicron can evade the immune protection generated by vaccines and natural infections, and suggests that new vaccines and treatment methods are needed.
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Mysterious immune cells may trigger inflammation in multiple sclerosis and other brain diseases
Time of Update: 2022-01-10
According to a new study by researchers from the Weill Cornell School of Medicine and the New York Presbyterian Church, a group of immune cells can prevent gastrointestinal inflammation under normal conditions, but is associated with multiple sclerosis (MS) and other brain inflammations.
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Zhang Jinzhi's laboratory published a paper in JOURNAL OF APPLIED ANIMAL RESEARCH
Time of Update: 2022-01-10
Title: Circular RNA transcriptome analysis responses to heat stress in the hypothalamus of sows ( IF=1. 727 )Authors: Ni, Yifan ; Cai, Jianfeng ; Chen, Qiangqiang ; Wu, Fen ; Hu, Jinping ; Zhang, Jinz
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Ketamine (K powder) treatment can quickly reduce depression and suicidal thoughts
Time of Update: 2022-01-10
This review published in the British Open Journal of Psychiatry combines evidence from a growing field of research on the potential benefits of ketamine for diseases for which effective treatments are limited .
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Sun Baolin's research group from the University of Science and Technology of China reveals the molecular mechanism of LcpB protein regulating cell wall synthesis and virulence of MRSA strains
Time of Update: 2022-01-10
aureus infection mechanism, relevant research results " LcpB IS A Pyrophosphatase Responsible for Wall teichoic acid Synthesis and virulence in Staphylococcus aureus Clinical "Isolate ST59" was published in the magazine " Frontiers in Microbiology " .
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The paper published by the Key Laboratory of Restoration Ecology in Cold Regions of Qinghai Province was selected as one of the "100 Most Influential Domestic Academic Papers in China in 2020"
Time of Update: 2022-01-10
The "Statistical Report on Chinese Sci-tech Papers 2021" (https:// "China Excellence According to the scientific paper report, the paper "The relationship between the biodiversity of the alpine grassland in the Qinghai-Tibet Plateau and the function of ecosystems" published in Biodiversity by doctoral student Zhang Zhonghua, researcher Zhou Huakun, researcher Zhou Huakun, and researcher Zhao Xinquan of the Northwest Plateau Institute of Biology of the Chinese Academy of Sciences was selected.
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The stools of patients with inflammatory bowel disease (IBD) contain more microplastics!
Time of Update: 2022-01-10
Now, researchers have published a report in the ACS Journal of Environmental Science and Technology that compared with healthy controls, people with inflammatory bowel disease (IBD) have more microplastics in their stools, which shows that these The fragments may be related to the disease process .
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Cysteinyl leukotriene and IL-25 produced by clustered cells synergistically initiate lung type 2 inflammation
Time of Update: 2022-01-10
The increase in pulmonary eosinophils is mainly mediated by the classic CysLT receptor1The activation of R, type 2 cytokines and innate immune cells requires signaling through CysLT1R and part of CysLT2R, clustered cells-specific deletionsLtc4s company, To produce the end enzymes required by CysLT, reduce lung inflammation and systemic immune response after inhalation of mold gas allergensAlternaria;At the same time blocking IL-25 further enhances this effect .
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Zhou Yufeng’s team first revealed the function and regulatory mechanism of circular RNA in allergic dermatitis and psoriasis in the Journal of Allergy and Clinical Immunology
Time of Update: 2022-01-10
The expression of hsa_circ_0004287 in PBMC of AD patients is up-regulated and negatively correlated with IL-6 and SCORAD Next, the authors constructed models of acute and chronic dermatitis in mice induced by calcipotriol (MC903) and 2,4-dinitrochlorobenzene (DNCB), and then applied the hsa_circ_0004287 overexpression plasmid locally with the help of in vivo transfection reagents To the skin of mice, the results showed that topical application of hsa_circ_0004287 plasmid significantly improved the skin inflammation in mice .
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Future trend: More detailed analysis of intestinal microbial strains and diseases and health
Time of Update: 2022-01-10
Inspired by the method of analyzing only the most variable regions in the human genome, the team began to find the minimum amount of sequence information needed from the microbiome data to determine the strains contained therein .
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New model creature: dwarf spotted octopus
Time of Update: 2022-01-10
"Compared with other octopuses, the Pacific striped octopus ( Octopus chierchiae ) has certain biological characteristics that make them more attractive and more suitable for laboratory research," said Bret Grasse, who wrote this article.
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The brain is not flexible, just look at the astrocytes
Time of Update: 2022-01-10
Specifically, they found that the ability of astrocytes to simultaneously regulate and integrate nearby synaptic plasticity is important for promoting cognitive flexibility .
Combining with the previous known that astrocytes release glutamate through Best1, the co-release of D-serine and glutamate indicates that astrocytes are ideal NMDAR activity and synaptic plasticity regulators .
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New progress has been made in the study of the abnormal regulation mechanism of platelet activating factor acetylhydrolase in ovarian cancer in Kunming plants
Time of Update: 2022-01-10
PAF-AH 1B2 knockdown tumor cells significantly down-regulate the expression of several key regulatory molecules in a variety of tyrosine kinase-mediated signaling pathways, and reduce the growth factor receptor pathway and PAF-AH 1B2- mediated cell proliferation.
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The research group of Yongzhong Du from the School of Pharmacy of Zhejiang University reported on Nano Today a light-controlled "drug-free" macromolecule...
Time of Update: 2022-01-10
Based on the work foundation of the research group's early-stage cell membrane surface receptor cross-linking to induce tumor cell apoptosis ( Chemical Science, 2020 ), in response to the problem of off-target chemotherapeutic drug targeting agents, this study designed an up-conversion nanoparticle, adapted The light-controlled "drug-free" macromolecules composed of body, water-soluble polymer and cinnamic acid .
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Nature review: The decline in human fertility may be related to fossil fuels
Time of Update: 2022-01-10
Chemical pollution caused by burning fossil fuels may be an important reason for the decline in sperm counts in men worldwide .
3. The decline in human fertility may be related to exposure to chemicals in fossil fuels, which can cause human reproduction problems and cancer .