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Evidence that common herpes virus causes multiple sclerosis
Time of Update: 2022-01-24
The research team examined the association between Epstein-Barr virus infection and MS by analyzing serum samples and medical data collected from a cohort of more than 10 million U.
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New therapeutic target for multiple myeloma
Time of Update: 2022-01-24
In 2016, the team discovered how bacterial lactones cause the clinical manifestations of Buruli ulcer: by targeting the transposon (Sec61) .
"This study provides proof-of-concept that the transposon is a new therapeutic target in multiple myeloma .
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PNAS: Previously little-known protein involved in metabolic pathway required for cancer cell survival
Time of Update: 2022-01-24
But now that its important role in AML cells has been discovered, Polyanskaya said, "Other researchers can use this system, tweak some other things, and really try and pinpoint the exact pathway .
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The sensory mechanisms that enable magnetic perception in life
Time of Update: 2022-01-24
The magnetite crystals that form inside special receptor cells in salmon and other animals may be related to ancient genetic systems that were developed from bacteria and passed on to animals through evolutionary genetics long ago .
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Preventive skin cancer vaccine
Time of Update: 2022-01-24
UV radiation from the sun causes oxidative stress, which increases the risk of developing skin cancers such as melanoma, explains Arup Indra, professor of pharmacy at OSU and leader of the study .
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Research and develop a new tool for base editing delivery - virus-like particles can be multi-organ targeted editing
Time of Update: 2022-01-24
11 in the journal Cell, a research team in David Liu's lab at the Broad Institute of MIT and Harvard has developed an engineered DNA-free virus-like particle (eVLP) that can efficiently package and delivery of base editors or Cas9 ribonucleoproteins .
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Autoimmune gastritis may be an important factor in gastric cancer
Time of Update: 2022-01-24
Given the increasing trend of autoimmune diseases, women with FMC are born later, which may explain the higher prevalence of autoantibodies in the ATBC study [9] .
pylori in the general population declines, an autoimmune drive may be an important factor in gastric cancer incidence .
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Harvard University discovers the mystery of "foot" genes forming "eyes"
Time of Update: 2022-01-24
Researchers from the FAS Center for Systems Biology have discovered an important gene network in squid eye development that is also known to play a key role in limb development in animals such as vertebrates and insects .
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Zhou Ming's research group from the Institute of Botany published a paper in Nature Commun. to reveal plant tissue-specific DN...
Time of Update: 2022-01-24
<> </>Recently, a research paper titled The CLASSY family controls tissue-specific DNA methylation patterns in Arabidopsis jointly completed by Zhou Ming's research group of the Institute of Botany and Julie Law 's research group of the Salk Institute of Biology in the United States was published in Nature Communications .
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Novel mechanisms by which vascular smooth muscle cells sense, transduce and respond to extracellular matrix stiffness
Time of Update: 2022-01-23
Here, we report that a collagen receptor in vascular smooth muscle cells, discoid domain receptor 1 (DDR1), acts as a mechanoreceptor to sense increased extracellular matrix stiffness in a ligand-independent manner and mediate Intracellular mechanical signal transduction, inhibits the contractile function of smooth muscle cells and promotes the synthesis of pro-inflammatory factors, causing changes in the microenvironment of the vessel wall and aggravating vascular sclerosis .
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A nationwide survey by the team of researcher Liu Jue from the School of Public Health shows that more than 90% of the research subjects are willing to receive a booster shot of the new crown vaccine
Time of Update: 2022-01-23
The results of the National Survey on China's New Crown Vaccine Booster Inoculation Willingness and Its Related Factors by the research team of Liu Jue from the School of Public Health of Peking University showed that more than 93.
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The research results of Prof. Ping Jianfeng and Prof. Ying Yibin's team (IBE) are published online in Nature Food
Time of Update: 2022-01-23
Therefore, in view of the practical difficulties of electric growth-promoting technology in agricultural applications, researchers proposed to replace the traditional high-voltage electrostatic field power supply with TENG to achieve self-powered electric-stimulated growth of crops .
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The research group of Meng Anming from the School of Life Sciences found that the second polar body of mouse embryos establishes cell fate asymmetry
Time of Update: 2022-01-23
Previous studies in mice found that after the second polar body of the fertilized egg was removed, the shape and number of cells of the blastocyst did not change when the embryo developed to the blastocyst stage.
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ITEWA team from Shanghai Jiaotong University Refrigeration Institute published research results on new thermally driven adsorption refrigeration materials in Nature Communications
Time of Update: 2022-01-23
Aiming at the problems of low performance of traditional adsorbents, high cost of metal organic frameworks (MOFs) and difficulty in large-scale production, this paper developed a new type of aluminum phosphate molecular sieve adsorption with SFO topology with excellent adsorption performance and potential for industrialization.
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Nat Commun︱ Shanghai Institute of Materia Medica collaborated to discover new targets for diabetes CREB/CRTC2 protein-protein interaction inhibitors lead compounds
Time of Update: 2022-01-23
Through in vitro and in vivo experiments, it was verified that the natural product Apidiline C binds to CREB, blocks the CREB/CRTC2 protein-protein interaction, regulates the expression of gluconeogenesis-related genes, and then exerts the therapeutic effect of reducing fasting blood glucose .
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scDIOR software breaks through the barriers of single-cell omics R/Python platform
Time of Update: 2022-01-23
The software unifies the data structure of multiple single-cell analysis tools, enables single-cell data to be quickly converted between different platforms, reduces storage and memory consumption, and significantly improves the efficiency of single-cell research .
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The scientific research achievements of Xu Yanhui's team were selected into the "Top Ten Progresses in China's Life Sciences" in 2021
Time of Update: 2022-01-23
Recently, the research results of Professor Xu Yanhui's team from Fudan Shanghai Medical University on the "Assembly Mechanism of Transcription Initiation Supercomplex" have been selected into the "Top Ten Progresses in China's Life Sciences" in 2021 announced by the Chinese Association for Science and Technology of Life Sciences .
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Cell sub-journal: Decoding epigenetic mechanisms of parent-specific gene activation
Time of Update: 2022-01-23
However, for about 1% of our genes, only the one inherited from the father or mother is active, and the other gene is inactive, a phenomenon known as genomic imprinting .
"There are almost three known epigenetic mechanisms that we can use to explain gene expression specific to all parents," Andergassen said .
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Declines in animal species dispersing seeds hinders ability of plants to adapt to climate change
Time of Update: 2022-01-23
These findings highlight the dynamic plant-animal interactions that support ecosystem function and illustrate worrisome feedbacks between biodiversity loss and the ongoing climate crisis .
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Science Sub-Journal: Scientific Explanation of "Temporary Visual Blindness"
Time of Update: 2022-01-23
"If our brains were constantly updating in real time, the world would be a jittery place, with shadows," said David Whitney, the study's senior author and professor of psychology, neuroscience and visual sciences at UC Berkeley.
