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The team of Professor Li Qian from the Center for Anesthesiology and Surgery published an article in Advanced Materials systematically summarizing the research progress of biomaterial-targeted treatment of myocardial ischemic injury and proposing...
Time of Update: 2022-01-24
Responsive biomaterials designed based on the characteristic ischemic microenvironment (IME) of the heart can target the delivery of therapeutic drugs to damaged cardiomyocytes, and have great therapeutic potential and application prospects in the field of ischemic cardiomyopathy .
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A new study provides a new therapeutic target for the treatment of sepsis
Time of Update: 2022-01-24
Image: The study also demonstrates that a drug originally developed to treat alcohol dependence can inhibit the activity of the molecule, preventing complications In an article published in the journal Blood, USP researchers and their collaborators propose a new strategy to prevent complications of sepsis .
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"Nature" challenges evolutionary DNA mutation theory!
Time of Update: 2022-01-24
"We've always thought of genetic mutations as basically random," said Grey Monroe, an assistant professor in the UC Davis Department of Plant Sciences and lead author of the paper .
"The plant has evolved a way to protect its most important places from mutation," Weigel said .
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UC Davis: Dried goji berries may prevent age-related vision loss
Time of Update: 2022-01-24
Researchers found that eating 28 grams (about 1 ounce or a handful) of goji berries five times a week for 90 days in 13 healthy participants between the ages of 45 and 65 increased the density of protective pigments in the eyes .
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The research results of Professor Han Jingyan's team were selected into the top ten academic progress of traditional Chinese medicine in 2021
Time of Update: 2022-01-24
The traditional method of regulating osmotic pressure cannot improve the damaged microvascular barrier, and the curative effect of treating edema is unsatisfactory .
On January 13, 2022, People's Daily announced the results of the selection of "Top Ten Academic Progresses in Traditional Chinese Medicine in 2021" https://m.
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Scientists achieve genome editing of vascular endothelial cells for the first time!
Time of Update: 2022-01-24
Image Credit: Pixabay/CC0 Public Domain"The nanoparticle we developed is a powerful new delivery system for genome editing in vascular endothelial cells, which may be used to help treat a variety of human diseases, including acute respiratory distress in severe COVID-19," said Zhao.
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PNAS Announces Breakthrough New Technology: Identifying Pathogenic Particles in Blood
Time of Update: 2022-01-24
He is the lead author of a recently published study describing how researchers took advantage of a new technology that allowed them to track specific protein particles in a patient's blood sample and measure their size in nanometers .
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Cancer Res from the University of Hong Kong: Determining new drug combinations for liver cancer through CRISPR-Cas9 screening
Time of Update: 2022-01-24
By combining CRISPR-Cas9 screening, focusing on a set of drug targets whose expression is upregulated in HCC cancer stem cells, the Hong Kong Polytechnic University research team found that the two combinations contained the common target NMDAR1, and the paired targets were two kinases (FLT4 and FGFR3) , and the corresponding inhibitors are all one-clone rafenib .
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Chinese scholars discover boson strange metal state in high-temperature superconductivity
Time of Update: 2022-01-24
51722204, 51972041), the team of Academician Li Yanrong from the University of Electronic Science and Technology of China and his collaborators have made progress in the field of high-temperature superconducting quantum phase transition, and discovered and confirmed the boson strange metal .
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"Nature Metabolism" scientists find for the first time a protein that can promote the autonomous browning of white fat!
Time of Update: 2022-01-24
Since obesity is determined by a variety of genetic and environmental factors, Luca Scorrano's team used identical twins as research objects, and adopted a unified method to measure mitochondrial protein levels in obese patients to explore the relationship between obesity and op1 expression in adipose tissue .
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Cell Rep identifies signaling mechanism in pancreatic cancer cells that may offer therapeutic targets
Time of Update: 2022-01-24
The results suggest that novel small-molecule drugs that inhibit ATR are being investigated for the treatment of several cancers, including PDAC, and could be used in combination with interferon "amplification" to block the escape ability of tumor cells .
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Chinese scholars find the relationship between neonatal jaundice and air pollution and build a predictive model
Time of Update: 2022-01-24
Sun Jianhua and Beifei's team started from the clinical phenomenon that "there seem to be more patients with neonatal jaundice during the period of high air pollution", established a multi-center cohort of healthy pregnant women and their newborn babies, and established a related prediction model .
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New understanding of the origin of life
Time of Update: 2022-01-24
So the team simulated the original conditions, growing six different cell lines in an environment where the only available nutrients were oleic acid vesicles (OAVs) rather than the more common glucose .
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First identification of Earth's earliest phototrophic eukaryotes
Time of Update: 2022-01-24
Marie Catherine Sforna, a postdoctoral researcher at the Laboratory for Early Traces of Life at ULiège University, has conducted a new scientific study of Congo Basin fossils under the supervision of Professor Emmanuelle Javaux .
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New GUT findings may help better diagnose and treat liver cancer
Time of Update: 2022-01-24
"The research team conducted a more detailed study of the specific pairing of an RNA-binding protein (CCT3) and a lncRNA molecule (LINC00326) .
There are many more combinations to studyThe researchers' findings provide insight into the interactions between RNA-binding proteins and lncRNA molecules and contribute to a better scientific understanding of their roles in tumors .
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"Neuron" Alzheimer's disease: Inflammatory markers evident in early stages
Time of Update: 2022-01-24
In recent years, evidence has shown that the brain's immune system and related inflammatory processes -- also known as "neuro-inflammation" -- contribute significantly to the development of Alzheimer's disease .
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JAMA Oncology Hearing different perspectives in the face of ADAURA study with stunning data
Time of Update: 2022-01-24
The results showed that at 24 months, among patients with stage II-IIIA NSCLC, the DFS rates in the osimertinib group and placebo group were 90% and 44%, respectively (HR=0.
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Nature sub-journal: Key signaling pathways involved in tumor formation
Time of Update: 2022-01-24
To identify and characterize these central control mechanisms, a research team led by Charité and Goethe University systematically searched for altered genes found in lymphomas, cancers of the lymphatic system .
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"A method for the construction of agricultural non-point source pollution ecological prevention and control plant community with myrtle as the dominant species" won the invention patent
Time of Update: 2022-01-24
The agricultural non-point source pollution ecological prevention and control plant community constructed by the invention can effectively increase the surface runoff time by 1.
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Evidence that common herpes virus causes multiple sclerosis
Time of Update: 2022-01-24
The research team examined the association between Epstein-Barr virus infection and MS by analyzing serum samples and medical data collected from a cohort of more than 10 million U.