-
"Science" cover: a milestone in flow cytometry!
Time of Update: 2022-02-20
BDX, a leading global medical technology company, announced today that a study conducted in collaboration with the European Molecular Biology Laboratory (EMBL) and published as a cover story in the January 21 issue of Science, describes the use of flow cytometry in A new BD innovation that adds fluorescence imaging and image-based decision-making to classify individual cells at exceptionally high speed, based on the visual details of each cell, not just the type or number of biomarkers present .
-
Science Announces Molecular-Level Analysis of World's First Omicron Spike Protein
Time of Update: 2022-02-20
Source: UBC School of Medicine"Understanding the molecular structure of the viral spike protein is important as it can help us develop more effective therapeutic Omicron and related variants in the future," said lead author Sriram Subramaniam, Ph. D.
-
"Nature" Stanford University What disease-causing changes occur in aging ribosomes
Time of Update: 2022-02-20
To address this question, researchers in the lab of Judith Frydman, the Donald Kennedy Chair in the Stanford School of Humanities and Sciences, focused on how age affects the function of ribosomes -- the ribosomes responsible for converting messenger RNA into proteins cellular mechanism .
-
How do we control the actions of neuronal "couriers"?
Time of Update: 2022-02-20
In a study published in December 2021 in the journal Development, the researchers describe how an enzyme called GSK3β acts as a stop switch for a motor protein called kinesin 1 .
-
NEJM: Pills extracted from human feces treat recurrent intestinal infections
Time of Update: 2022-02-20
One option, a pill containing bacterial spores isolated from human feces, has now been successful in a Phase 3 trial, paving the way for the first approval of this type of drug .
The new pill, called SER-109, made by Seres Therapeutics, is extracted from human feces and purified to screen for resident microbes .
-
Jia Hao and others from the School of Basic Medicine published a new method for the treatment of oral leukoplakia in the journal Molecular Therapy...
Time of Update: 2022-02-20
The team's researchers further used high-throughput genetic screening to find that compared with normal tissues, the long-chain non-coding RNA IFITM4P was highly expressed in human oral leukoplakia/squamous cell carcinoma tissues, and its expression level increased with the degree of malignancy.
-
"Nature Biotechnology" RNA editing has reached a new level!
Time of Update: 2022-02-20
This study develops a set of guide RNAs, gRNA clusters, that bind target mRNAs in a multivalent manner without the need for exogenous proteins, utilize endogenous ADAR enzymes to enable high-precision and high-efficiency editing, and enable editing that cannot be achieved by gRNA design targeted editing of previous sequences .
-
Cell's new discovery: Neurons that control movement
Time of Update: 2022-02-20
"Our findings also have the potential to lead to new ideas for therapeutic avenues, whether they involve spinal cord injury or the treatment of neurodegenerative diseases that affect movement and motor control .
-
The achievements of Liu Tao's team were selected as the top ten domestic medical science and technology news in 2021
Time of Update: 2022-02-20
Liu Tao's team from Peking University School of Pharmacy and Ye Haifeng's team from East China Normal University School of Life Sciences jointly developed a gene "switch" that rapidly regulates insulin expression, providing a new tool for synthetic biology and cell therapy research .
-
Lactic acid is involved in the regulation of obesity-induced insulin resistance
Time of Update: 2022-02-20
On January 14, 2022, the research group of Chen Yan from Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences published an online article entitled "Lactate is a key mediator that links obesity to insulin resistance via modulating cytokine production from adipose tissue" in Diabetes , a well-known international journal in the field of diabetes.
-
Nature Cancer: How melanoma prepares lymph nodes for tumor spread
Time of Update: 2022-02-20
Melanoma cells release small cell envelopes that contain the protein nerve growth factor receptor, which primes nearby lymph nodes for tumor metastasis, according to a new study by Weill Cornell Medicine researchers .
-
Watching dramas for 4 hours a day increases the risk of blood clots by 30%
Time of Update: 2022-02-20
According to the paper published in the "European Journal of Preventive Cardiology" on the 20th, people who watch TV for 4 hours or more a day have a 35% higher risk of developing blood clots .
-
Shanghai Jiaotong University Jin Fangming's research team's paper was reviewed by Michael J. Russell, founder of the theory of the origin of life under the sea
Time of Update: 2022-02-20
Last month, the research team of Professor Jin Fangming from the School of Environmental Science and Engineering, Shanghai Jiao Tong University published a long-chain hydrothermal conversion of carbon dioxide production in the Proceedings of the National Academy of Sciences of the United States of America (PNAS).
-
New high-throughput method greatly expands view of how mutations affect cells
Time of Update: 2022-02-20
"While the team focused on cancer-related genes and mutations in this study, they noted that sc-eVIP is genetically indeterminate and highly scalable, using single-cell RNA sequencing as a readout, providing An efficient and generalizable method to generate rich phenotypic data .
-
Nat Cancer: Can eating pig trotters prevent cancer cells from metastasizing?
Time of Update: 2022-02-20
So the researchers wondered, could cancer cells remain dormant if the amount of collagen type III in the tumor microenvironment increased?
In animal experiments, they found that after increasing collagen type III, cancer cells that had metastasized to different sites did enter hibernate state .
-
Nature: Studying the roots of aging through the ribosome
Time of Update: 2022-02-20
Using models of human aging, yeast and roundworms, Stanford University researchers traced this problem in aging to age-dependent damage to the mechanisms that produce new proteins .
-
Artificial intelligence, cloud computing, extended reality, etc. will support five technology trends in the medical and health field in 2022
Time of Update: 2022-02-20
In the medical field, this trend includes digital simulations of "virtual patients" -- those testing drugs and treatments, with the aim of shortening the time it takes for a new drug to move from the design stage to the generic stage .
-
PNAS discovers pathogenesis of rare childhood blood cancer
Time of Update: 2022-02-20
Dr Xiang said: "Because we have the structure of this region and we know its function, we are fully confident that we have identified a key therapeutic target for the treatment of myelodysplastic syndromes in children derived from SAMD9 and SAMD9L mutations .
-
BD Showcases Milestones in Cell Sorting on the Cover of Science
Time of Update: 2022-02-20
The new technology adds fluorescence imaging and image-based decision-making, enabling the sorting of individual cells at very high speeds and based on microscopic images of each cell, not just the type or number of biomarkers .
-
New discovery: Targeting bone cells better at targeting leukemia than malignant stem cells?
Time of Update: 2022-02-20
In the same study, Kousteni and Galán-Díez observed continuously elevated levels of kynurenine and SAA1 in patients with AML and in patients with myelodysplastic syndrome (MDS) .
