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Study finds hemoglobin is a chemosensory signal for mother mice to protect pups
Time of Update: 2022-03-06
The researchers then first exposed male mice to a small amount of blood and observed blood-dependent activation of peripheral sensory neurons located in the vomeronasal organ of the nose .
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World's first genome editing tool for ticks
Time of Update: 2022-03-06
In the iScience study, researchers developed a successful tick embryo injection protocol and targeted gene disruption using CRISPR-Cas9 using two approaches: embryo injection and receptor-mediated ovarian cargo transduction ( ReMOT Control) - a less labor-intensive approach to gene editing in arthropods .
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Chinese scholars discover a new mechanism for improving chronic migraine with traditional Chinese medicine prescriptions
Time of Update: 2022-03-06
Tuwuzhuyu Decoction relieves pain sensitization in chronic migraine by increasing central and peripheral 5-HT, inhibiting CGRP release Funded by the National Natural Science Foundation of China (Grant No.
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Shenzhen University discovers three new rare bacterial phyla and reveals their metabolic characteristics and evolutionary history
Time of Update: 2022-03-06
Recently, Li Meng's research group from the Institute for Advanced Study of Shenzhen University published a research paper entitled Genomic insights into versatile life> .
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Microsystems & Nanoengineering Publishes Latest Results in Circulating Tumor Cell Detection
Time of Update: 2022-03-06
In this study, inspired by the windmill airflow disturbance model in nature, researchers developed a novel integrated microdevice of a pinwheel-like array membrane for efficient, clogging-free and self-mixing enrichment of circulating tumor cells .
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Nature sub-journal: Compressing gene banks to expand accessibility and research opportunities
Time of Update: 2022-03-06
This "attrition" largely preserves the image while greatly reducing file size and provides inspiration for new research directions in genomics, said Justin Pritchard, assistant professor of biomedical engineering .
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'Wonder' nanoparticles from corn: an effective and affordable cancer treatment
Time of Update: 2022-03-06
Using this knowledge, researchers from Tokyo University of Science (TUS) have recently developed bionanoparticles with anticancer activity, using corn as a raw material .
In a series of promising results, cNPs were taken up by multiple cell types, including clinically relevant colon tumor cells (cancer cells from mice), RAW264.
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Unexpectedly high levels of harmful chemicals found in nail salons
Time of Update: 2022-03-06
"We were very surprised to find that nail salon workers are exposed to some chemicals 30 times more than in households, and more than e-waste disposal facilities," said co-author Miriam Diamond, a professor in the Department of Earth Sciences at the University of Toronto.
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Robot that can check blood pressure
Time of Update: 2022-03-06
student Tae-Ho Kim and a team from SFU's Additive Manufacturing Lab, Kim and the researchers replicated the leech's folding mechanism in a 3D-printable origami sensor they designed, replacing the traditional blood pressure procedure .
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Cell Discovery Tang Fuchou's team and Hao Jihui's team work together to reveal the epigenetic regulation mechanism of pancreatic ductal adenocarcinoma
Time of Update: 2022-03-06
Characterization of DNA methylation and chromatin status in pancreatic ductal adenocarcinoma tumor cells and normal epithelial cells (2) In pancreatic ductal adenocarcinoma tumor cells, DNA methylation in the promoter regions of hundreds of genes was strongly up-regulated, and the corresponding chromatin changed from an open state to a closed state, and showed a high degree of consistency in all patients .
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Genome-wide characterization of SARS-CoV-2 cytopathic proteins in the search for antiviral targets
Time of Update: 2022-03-06
We sought to identify antiviral targets through genome-wide identification of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins that are critical for viral pathogenesis and cause deleterious cytopathic effects .
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A new microscope allows high-throughput 3D adaptive optics imaging
Time of Update: 2022-03-06
About a year ago, a research team led by Professor CHOI Wonshik from the Centre for Molecular Spectroscopy and Dynamics (CMSD) at the Institute for Basic Sciences (IBS) demonstrated an imaging technique called "reflection matrix microscopy" that combines hardware and the ability to compute advanced adaptive optics .
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The research team of Feng Xu and Liu Chuan from the School of Physics has made new progress in the study of lattice quantum chromodynamics of nuclear structures
Time of Update: 2022-03-06
Studying the composition of quarks and gluons of nucleons is of great significance for understanding the basic laws of strong interaction and the deep structure of matter; this is also the future big scientific device - China Polarized Electron Ion Collider (EicC) and American Polarized Electron One of the important physical targets of the ion collider (EIC) .
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Large-scale neural recordings at single-neuron resolution in human cortex using neural pixel probes
Time of Update: 2022-03-06
The goal of this report in Nature Neuroscience is to develop a technique that uses modified neuropixel probes to record brain activity in human patients undergoing neurosurgery in the operating room .
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The team of Professor Yin Yuxin of Peking University and the team of Academician Wang Jun cooperated to develop a new method for early detection of lung cancer combined with metabolome and artificial intelligence
Time of Update: 2022-03-06
Yuxin Yin from Peking University School of Basic Medicine and the team of Academician Wang Jun from People's Hospital jointly published an online publication titled " Lung cancer scRNA-seq and lipidomics reveal aberrant lipid metabolism for early-stage " in the journal Science Translational Medicine.
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A microbial compound in the gut can lead to anxiety-producing behaviors, Nature finds
Time of Update: 2022-03-06
Needham/CaltechA Caltech-led team has found that a small-molecule metabolite produced by bacteria in the guts of mice can enter the brain and alter the function of brain cells, leading to increased anxiety in the mice .
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Astellas Announces Interim Safety Data for AT845: Good Safety and Tolerability!
Time of Update: 2022-03-06
Developed for the treatment of late-onset Pompe disease (LOPD), AT845 efficiently transduces a functional GAA gene for direct delivery into disease-affected tissues that express GAA, including skeletal and cardiac muscle .
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Nature Methods Publishes New Method to Improve Single-Cell RNA Sequencing Efficiency
Time of Update: 2022-03-06
Single-cell RNA sequencing (scRNA-seq) is a breakthrough technology that allows scientists to analyze the gene expression of individual cells in mixed populations .
"DisCo SolutionsA research team led by Deplancke has now developed a new method that allows scRNA-seq to efficiently process samples with low cell numbers .
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Mystery of cancer spread found in Nature sub-journal
Time of Update: 2022-03-06
The study, led by researchers at NYU Grossman School of Medicine and the NYU Courant Institute for Mathematical Sciences, used a new technique to measure when cell populations move along tissue membranes and into position in developing animals.
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Arvinas Announces Latest Results of Androgen Receptor PROTAC Therapy
Time of Update: 2022-03-06
Arvinas announced today that it has published new data showing that bavdegalutamide (also known as ARV-110), a novel PROTAC protein degrader targeting the androgen receptor (AR), targets metastatic castration-resistant prostate cancer (mCRPC), Continue to provide evidence of antitumor activity and patient benefit .
