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Huazhong University of Science and Technology's Nature sub-issue: BTNL2 is a new potential target for anti-tumor immunotherapy
Time of Update: 2022-03-07
On February 14, 2022, the team of Professor Wang Chenhui from the School of Life Science and Technology of Huazhong University of Science and Technology published the title "Cancer cell-expressed BTNL2 facilitates tumor immune escape via engagement with IL-17Aproducing γδ T cells" in the international authoritative journal "Nature Communications" latest research results .
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Proteins that control tissue sensing, response to mechanical forces discovered
Time of Update: 2022-03-07
To demonstrate how tension affects tissue growth, the researchers set up an experiment to see how human cancer cells convert mechanical information into biochemical signals in vitro, Leckband said .
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Wuhan Botanical Garden has made new progress in the biogeographical research of Podophyllum subfamily
Time of Update: 2022-03-07
Secondly, the fossil-corrected loose molecular clock and the reconstruction of the ancestral distribution area show that the Podophyllum subfamily originated in the Himalayas - Hengduan Mountains region in the late Eocene , differentiated in the middle Miocene ( about 13.
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Genetically engineered microorganisms with kill switches
Time of Update: 2022-03-07
Also, in some cases, the kill switch might not fire for days .
Moen, for example, is interested in developing genetically engineered microbes to eat plastic as a way to deal with hazardous waste .
Genetically stable CRISPR-based kill switches for engineered microbes .
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PLOS: How the enteric nervous system affects the gut microbiome
Time of Update: 2022-03-07
A new study from the University of Oregon shows that nerves in the gut help regulate the acidity of the gut .
To make this connection, Eisen and Gillette studied a zebrafish with a genetic mutation that caused the loss of nerves in the gut .
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'Broken Heart Syndrome' Is Real and Can't Be Ignored - 'It's Totally Biological'
Time of Update: 2022-03-07
" April Stempien-Otero, a cardiologist at the University of Washington Medical Heart Institute, sees cases every year that are severe enough to require treatment in the intensive care unit .
"It's very touching to take care of these people when they realize this emotional event is the cause of their heart problems .
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The University of Hong Kong's latest paper: How guard cell chloroplasts obtain energy
Time of Update: 2022-03-07
Boon Leong Lim's research group at the University of Hong Kong used a plant fluorescent protein sensor to observe the production of ATP and NADPH in real time in the mesophyll cells and chloroplasts of the simulated plant Arabidopsis thaliana .
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The Nature sub-issue of Xiamen University: Construction of a new live varicella vaccine with dual attenuated skin and nerve properties
Time of Update: 2022-03-07
The laboratory and Rutgers University New Jersey School of Medicine have constructed the first new live attenuated varicella vaccine VZV-7D with dual attenuated skin and nerve properties, and verified the preclinical safety of the vaccine by using various in vitro and in vivo model systems and immunogenicity, providing important support for the vaccine to enter clinical trials .
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Nature Biotechnology unveils a more efficient RNA editing technique
Time of Update: 2022-03-07
To overcome these problems, Mali and colleagues designed a new guide RNA that recruits the cell's own ADARs very efficiently to edit precise target RNA regions .
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USTC establishes new method for de novo protein design
Time of Update: 2022-03-07
(a) The minima on the energy surface of the SCUBA main chain corresponds to the designable main chain structure of the protein, that is, the lowest free energy structure under a specific amino acid sequence; (b) The statistical energy term represented by neural network in SCUBA; (c) and (d ) A method framework for learning analytical energy functions from protein structure raw data using a nearest neighbor counting (NC)-neural network (NN) approach .
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The enteric nervous system regulates intraluminal pH: altering the microbial environment for gut health
Time of Update: 2022-03-07
A new study from the University of Oregon shows that nerves in the gut help regulate the acidity of the gut .
To make this connection, Eisen and Gillette studied a zebrafish with a genetic mutation that caused the loss of nerves in the gut .
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Nature sub-journal discovers molecular mechanism of cerebral venous thrombosis
Time of Update: 2022-03-07
Scientists from the Rudolf Virchow Center for Integrative and Translational Bioimaging at the University of Würzburg (RVZ) and the University Hospital Würzburg, in collaboration with colleagues from Tübingen and Greifswald at Transregio Center (SFB TR) 240 in collaboration, has now been able to show for the first time that activation of two specific receptors on the surface of platelets leads to cerebral venous thrombosis .
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The first Omicron variant in white-tailed deer
Time of Update: 2022-03-07
International war "epidemic" operationScience and Technology Daily (Reporter Liu Xia) According to reports from Fox News and CBS on February 9, researchers at Penn State University in the United States said they found a mutant strain of the new coronavirus in New York white-tailed deer.
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"Science" p53 protein actually plays a key role in tissue repair
Time of Update: 2022-03-07
Eugenia Piddini, Professorial Research Fellow in Cell Biology and Wellcome Trust School of Cellular and Molecular Medicine (CMM) Senior Research Fellow at the University of Bristol, UK, and lead senior author of the work, said: "Our findings improve our ability to An understanding of the mechanisms by which cells repair tissue can be used to develop systems that accelerate wound healing .
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A new treatment option for type 1 diabetes?
Time of Update: 2022-03-07
Is improving the patient's intestinal flora beneficial to the treatment of type 1 diabetes?Screenshot source: MicrobiomeA recent study published in "Microbiome" showed that taking plant-based food supplements can improve the gut microbiota in patients with type 1 diabetes, which may increase the production of short-chain fatty acids, which can enhance the function of the immune system.
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A durable model of human germ cell precursors
Time of Update: 2022-03-07
But Shioda and colleagues explain reporting in the Journal of Stem Cells that they have developed a method to maintain the germ-cell-like function of hPGCLCs in cell culture without the need for special handling, and the cells survive and continue to replicate for at least five months without losing the original germ- cell-like features .
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Ovarian cancer's secret hideout revealed
Time of Update: 2022-03-07
"By increasing our understanding of how tumor genes trick the immune system, we will be able to develop more effective ways to activate the body's own immune defenses to kill cancer cells," Inga-Maria said .
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New approach to targeting mutated RAS offers hope for cancer patients
Time of Update: 2022-03-07
Because the R15 monomer does not easily enter cells, O'bryan explained that a small molecule targeting the nucleotide-free mutant RAS protein would be a more effective treatment .
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When seeking TBI therapy, astrocytes may be the bullseye
Time of Update: 2022-03-07
"Previous research by my lab and others has found that pharmacological inhibition of MAGL reduces neuropathology in traumatic brain injury and improves cognitive function," said senior author Chu Chen, Ph. D.
Knockout of MAGL in astrocytes significantly reduced brain injury disease effects and cognitive decline in TBI animals .
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Brain training with neurofeedback can enhance cognitive function
Time of Update: 2022-03-07
Previous studies have reported a positive correlation between increased brain activity during brain training and improved cognitive function, and the research team is eager to discover whether brain training, which enhances brain activity through neurofeedback, has a positive effect on cognitive performance influence .
