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Early ivermectin treatment fails to reduce COVID-19 hospitalizations
Time of Update: 2022-04-16
3% in the placebo group,There was one primary outcome event: COVID-19 hospitalization or worsening of COVID-19 in emergency department visits, defined as more than 6 hours of observation within 28 days after randomization; relative risk 0.
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Earthworms like to eat some plastic, but their digestive side effects are unclear
Time of Update: 2022-04-16
By placing earthworms in containers filled with different types of plastics at specific locations in the soil, the researchers found that the earthworms preferred either biobased polylactic acid (PLA) pellets or petroleum-derived polyethylene terephthalate (PET) Particulate soil, but actively steer clear of some semi-synthetic plastics .
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Genetic mapping identifies heart disease risk in people with type 2 diabetes
Time of Update: 2022-04-16
In this study, the researchers explored whether genetic variants associated with high blood pressure were also associated with later heart disease or stroke in people with type 2 diabetes, and used this information to determine a risk score .
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"Cell" Westlake University team found evidence that bacteria help cancer cells metastasize!
Time of Update: 2022-04-16
Although the study revealed a clear role for intratumoral bacteria in promoting metastatic colonization of cancer cells, the authors did not rule out the possibility that the gut microbiota and immune system might work together with intratumoral bacteria to determine cancer progression .
Tumor resident intracellular microbiota promotes metastatic colonization in breast cancer10.
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What survival advantage did Tyrannosaurus rex's short arms have?
Time of Update: 2022-04-16
rex's short forelimbs evolved to do, it's better to ask how those forelimbs benefited the animal as a whole, Padian said .
rex ancestors had longer arms, so they were smaller in size and joint mobility, Padian noted .
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Professor Li Hongye's team from the College of Agriculture published a paper in Microbiome to reveal the response and underlying mechanism of plant phyllosphere microbiome to pathogen invasion
Time of Update: 2022-04-16
Multiple microbiome signatures indicated a shift in the phyllosphere microbiome infested by Citrus black spot, highlighted by a significant reduction in microbial community uniformity, the emergence of a large number of new microorganisms, and an intensified microbial network .
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Evidence that vitamin K is beneficial to the rat brain
Time of Update: 2022-04-16
In a new study in rats, scientists report evidence that vitamin K can help prevent cognitive decline associated with Alzheimer's and other forms of dementia .
The new study sheds light on some of the biological pathways by which vitamin K appears to help preserve cognitive function .
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Cell's new discovery solves a century-old mystery
Time of Update: 2022-04-16
A team led by researchers at Utah State University has discovered a molecule produced by male parasites called schistosomes that promotes sexual maturation in females of these species .
They soon discovered that a gene called gli1 appeared to play a key role in promoting female sexual maturity in males .
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Cell Stem Cell: Gene deletions behind abnormalities in blood cancer cells
Time of Update: 2022-04-16
Summarizing the recent findings, Doulatov said, "We show that lamin B1 deletion leads to alterations in stem cell function, nuclear shape, and leukemia progression .
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The research group of Shao Lei and Zhang Wenming of Shanghai Jiaotong University has made a breakthrough in the field of dynamic testing of MEMS chips
Time of Update: 2022-04-16
Recently, the team of Shao Lei of JI, Shanghai Jiaotong University, Zhang Wenming of the School of Mechanical and Power Engineering, Jason Gorman of the National Institute of Standards and Technology, and the team of Amit Lab of Cornell University published the title "Femtometer" in the internationally renowned academic journal "Nature Communications".
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A new molecule holds promise for cancer and rare diseases
Time of Update: 2022-04-16
Their work initially focused on blocking the interaction of members of the CDC42 family of GTPases with the key kinase PAK1, which is amplified in breast, colon and other cancers, and in the pathology of rare diseases such as neurofibromatosis and Ewing's sarcoma active .
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How polygenes affect vision development and cause rare vision impairment
Time of Update: 2022-04-16
Now, in a study published in the journal Ophthalmology, researchers combining data from more than 900 cases around the world have been able to identify the spectrum of genetic changes behind these foveal defects and, crucially, they Occurs during the development of an unborn baby .
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Nature sub-journal: Genetic 'hot spots' that accelerate/slow down brain aging
Time of Update: 2022-04-16
1 million markers screenedAfter calculating the rate of brain tissue changes in 15,000 people of different ages, the researchers screened 1 million markers across their genomes to detect 15 genomic loci specific, the physical location of a gene or other DNA sequences - they accelerate changes in brain tissue .
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Nature Immunology: How Vaccination Before and After Primary Infection Affects Immune Responses
Time of Update: 2022-04-16
Jude Children's Research Hospital assessed the impact of SARS-CoV-2 vaccination and infection on the immune system .
"If you become infected, the vaccine will still activate and amplify your immune response in a protective way," said co-corresponding author Paul Thomas, PhD, of St.
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Degeneration of neurons, not sleep deprivation, makes Alzheimer's patients drowsy
Time of Update: 2022-04-16
"We were able to show what our previous research had pointed out -- that in Alzheimer's patients who need to nap all the time, the disease damages the neurons that keep them awake," says neuropathologist Grinberg, who works with psychiatrists J.
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Mini Liver on a Chip
Time of Update: 2022-04-16
"In recent years, thanks in large part to advances by researchers at McDevitt and Gladstone, the emergence of 3D liver organoids has provided a new, more realistic way to study the interactions between hepatocytes, hepatitis C virus, and T cells.
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Key to early detection of ovarian cancer may be fallopian tubes
Time of Update: 2022-04-16
For some, taking a family history and seeking genetic testing to identify mutations in genes, such as BRCA1 and BRCA2, is a way to detect this cancer risk early .
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Xiao Bailong, School of Pharmacy, Tsinghua University/Li Xueming, School of Life Sciences, revealed the tension sensing mechanism of PIEZO1 on lipid membranes
Time of Update: 2022-04-16
Figure 1 Schematic diagram released by the 2021 Nobel Committee on Physiology or Medicine summarizing the discovery of PIEZO (top half), the physiopathological functions it mediates such as touch and proprioceptive perception (bottom half right), as well as structural models and mechanical forces Perception Hypothesis Conjecture (bottom half left) .
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The team of Yin Huancai of Suzhou Institute of Medicine and Engineering has made progress in the development of a portable nucleic acid rapid detection system for pathogens
Time of Update: 2022-04-16
In response to the above-mentioned needs for rapid nucleic acid detection, researcher Yin Huancai, who has long focused on high-sensitivity molecular diagnostic technology, combined with researcher Ma Fuqiang and related scientific research forces, and with the support of the self-deployed project of Suzhou Institute of Medical Technology, launched a loop-mediated isothermal amplification ( LAMP ) technology ( Loop-mediated isothermal amplification ).
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Study finds inhibition of PDK1 holds promise for acute myeloid leukemia
Time of Update: 2022-04-16
Related research results were recently published in the journal Nature Communications with the title "The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia" .
