-
The culprit behind rising antibiotic resistance -- the overlooked jumping gene
Time of Update: 2022-04-17
So, what are the underlying forces driving this natural selection, the researchers ask?In the newly published paper, You and his postdoc Yao Yi suggest that this mysterious mechanism may be antibiotic-mediated selection for "jumping genes" (called transposons) that switch resistance genes from The chromosomes of the cells are carried to the plasmids .
-
First detection and isolation of active SARS-CoV-2 in a hospital setting
Time of Update: 2022-04-17
This study strongly supports the aerosol transmission route of SARS COV-2 and urges revision of the infection control framework for COVID-19 to include airborne transmission .
-
BRCA: 30 Years of Wind and Rain from Gene Identification to Targeted Therapy
Time of Update: 2022-04-17
The story of the classic tumor suppressor genes BRCA1 and BRCA2 began in 1990 when Mary-claire King's team at the University of California, Berkeley discovered that human chromosome 17q21 may be the location of the susceptibility gene for early-onset hereditary breast cancer Speaking of.
-
It took WHO two years to finally admit that the new coronavirus can be 'airborne'
Time of Update: 2022-04-17
Amid the wave of desperate news for the year-end holiday, a team of researchers has welcomed a development that never seemed to come --On December 23, the World Health Organization finally acknowledged a word it previously seemed unable to use for the SARS-CoV-2 virus: "airborne .
-
Building an African Biobank
Time of Update: 2022-04-17
"I really wanted to target my research to populations that have been forgotten over time, such as Africans, African Americans, Latinos and Indigenous peoples," Tcheandjieu said .
-
Combining biomarkers can identify common cognitive disorders
Time of Update: 2022-04-17
"When we combined biomarkers of vascular injury with the protein fragments we identified, the potential to separate patients with subcortical small vessel disease from controls, patients with Alzheimer's disease and mixed dementia," Kettunen said.
-
Meeting all primary and secondary endpoints BMS announces Phase III clinical results for mavacamten
Time of Update: 2022-04-17
Recently, Bristol-Myers Squibb (BMS) announced the latest phase 3 clinical trial results of a potential "first-in-class" cardiac myosin allosteric inhibitor mavacamten for the treatment of obstructive hypertrophic cardiomyopathy (oHCM) .
com/iframes/press-releases/press-release-details/2022/Bristol-Myers-Squibb-Announces-Data-from-EXPLORER-LTE-Demonstrating-Sustained-Improvements-in-Clinically-Meaningful-Cardiovascular-Outcomes-at- Weeks-48-and-84-in-Patients-with-Symptomatic-Obstructive-Hypertrophic-Cardiomyopathy-Receiving-Mavacamten/default.
-
South China Botanical Garden discovers how changes in precipitation patterns affect soil organic carbon accumulation
Time of Update: 2022-04-17
The study speculates that the increase in microbial biomass and changes in the contribution of residual carbon to soil organic carbon caused by increased rainfall in the wet season will enhance the carbon sequestration capacity of tropical forest soils (Figure 3 ) .
-
Wuhan Botanical Garden and others publish the genome of American yellow lotus for the first time
Time of Update: 2022-04-17
Recently, The Plant Journal published an article titled "Comparative analyses of American and Asian lotus genomes reveal insights into petal color, carpel thermogenesis and domestication" from the collaboration of Wuhan Botanical Garden, Chinese Academy of Sciences and Fujian Agriculture and Forestry University , which assembled the first American The complete genome of Huanglian reveals the formation mechanism of the color difference between American and Asian lotus, carpel thermogenesis and other traits .
-
Submission of Marketing Application for Radioimmunotherapy for the Treatment of Neuroblastoma in Children
Time of Update: 2022-04-17
Y-mAbs Therapeutics announced today that it has completed the submission of a Biologics License Application (BLA) to the U.
"References:[1] Y-mAbs Announces Submission of Omburtamab Biologics License Application to FDA.
Retrieved April 1, 2022, from https:// -mAbs-Announces-Submission-of-Omburtamab-Biologics-License-Application-to-FDA.
-
New achievements of Chinese scholars reveal nonlinear changes in the interaction between sustainable development goals
Time of Update: 2022-04-17
The SDGs cluster diagram of the synergy network can clearly reflect the change process of first decoupling and then recoupling between SDGs with the level of sustainable development (Figure) .
-
TNBC treatment breakthrough: mRNA therapy + PD-L1 inhibitor greatly enhances the efficacy of immunotherapy
Time of Update: 2022-04-17
A team from the Hospital del Mar Medical Research Institute found that in triple-negative breast cancer (TNBC), cancer stem cells are able to evade the immune system, and that increased expression levels of a protein called LCOR (ligand-dependent corepressor) can interfere with this.
-
The Art of Smell: The Brain's Smell Process Is Both a Painting and a Symphony
Time of Update: 2022-04-16
When the centrifugal fibers are in another state, cells in the piriform cortex detect and classify odors through patterns that depend on brain activity, improving accuracy and speed .
-
Earthworms like to eat some plastic, but their digestive side effects are unclear
Time of Update: 2022-04-16
By placing earthworms in containers filled with different types of plastics at specific locations in the soil, the researchers found that the earthworms preferred either biobased polylactic acid (PLA) pellets or petroleum-derived polyethylene terephthalate (PET) Particulate soil, but actively steer clear of some semi-synthetic plastics .
-
Early ivermectin treatment fails to reduce COVID-19 hospitalizations
Time of Update: 2022-04-16
3% in the placebo group,There was one primary outcome event: COVID-19 hospitalization or worsening of COVID-19 in emergency department visits, defined as more than 6 hours of observation within 28 days after randomization; relative risk 0.
-
milestone!
Time of Update: 2022-04-16
Analyses of genes and biological mechanisms point to schizophrenia from disruptions in communication at synapses (where neurons connect), and shed light on how different variants in the same gene can affect disease risk for psychiatric and neurodevelopmental disorders .
-
Wang Dehua and Zhang Xueying's team revealed the mechanism of high salt tolerance in desert rodents through the "microbiota-gut-kidney" axis
Time of Update: 2022-04-16
A long-term high-salt diet in humans can easily cause a series of diseases such as high blood pressure, heart disease, kidney disease, and cerebral hemorrhage. However, some animal species can stay
-
Tiny jumping genes blamed for rising antibiotic resistance
Time of Update: 2022-04-16
So, what are the underlying forces driving this natural selection, the researchers ask?In the newly published paper, you and his postdoc Yao Yi suggest that this mysterious mechanism may be antibiotic-mediated selection of "jumping genes" (called transposons) that switch resistance genes from The chromosomes of the cells are carried to the plasmids .
-
NEJM: Is chemotherapy necessary for low-risk thyroid cancer?
Time of Update: 2022-04-16
In this multicenter, randomized, controlled trial involving patients with low-risk differentiated thyroid cancer, researchers demonstrated for the first time that patients who did not receive radioactive iodine after thyroidectomy had no worse prognosis than those who received radioactive iodine .
-
Biodegradable gel boosts immune system's attack on several types of cancer
Time of Update: 2022-04-16
Tested in mice, the gel releases the drug and specialized antibodies while destroying immune-blocking cells called macrophages from the surgical site and activating T cells that enable them to attack cancer .
