-
Wang Jiancheng's team published a review article in the Journal of Controlled Release: Non-viral vectors for RNA delivery
Time of Update: 2022-04-21
Recently, Wang Jiancheng's team from the State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmacy, Peking University published a review article in the Journal of Controlled Release , No.
-
Nat Biotech: Same-day identification of pathogenic variants with ultrafast nanopore sequencing in just 8 hours
Time of Update: 2022-04-21
The researchers developed the process based on Oxford Nanopore's high-throughput sequencing device PromethION 48, combined with an optimized sample preparation scheme, parallel sequencing on 48 sequencing chips, and rapid data analysis, which is expected to help doctors quickly diagnose critically ill patients.
-
Professor Zhang Hongquan's team discovered a new molecular mechanism by which oxidative stress regulates the activation of Hippo signaling pathway and inhibits the growth of lung cancer cells
Time of Update: 2022-04-21
On March 30, 2022, Professor Zhang Hongquan's team from Peking University School of Basic Medicine published a long research paper titled "Oxidative stress-CBP axis modulates MOB1 acetylation and activates the Hippo signaling pathway" in the journal Nucleic Acids Research, revealing that The role and molecular mechanism of oxidative stress regulating Hippo signaling pathway activation and inhibition of lung adenocarcinoma cell growth .
-
Tumor cells in some childhood leukemia block new neuron formation
Time of Update: 2022-04-21
Tumor cells that colonize this area of the brain prevent the differentiation of new neuronsResearch led by the Universidad Complutense de Madrid (UCM) has shown that the subventricular neurogenic niche is an area of the brain where tumor cells can evade chemotherapy treatment and reappear later, causing childhood acute lymphoblastic leukemia ( ALL) and prevent the formation of new neurons .
-
Rogue immune cells that steal proteins may worsen multiple sclerosis
Time of Update: 2022-04-21
Now, a new study shows that when some T cells go down the road to destruction, they pick up an important protein from another type of immune cell called a B cell .
Multiple sclerosis patients often receive treatments that target immune cells that carry CD20, which scientists have traditionally thought of as B cells .
-
A 'perfect storm' of genetic mutations is responsible for rare brain malformation
Time of Update: 2022-04-21
"Right now we can develop blood tests to identify these mutations in the brain, and in the future, we can develop treatments to inhibit the mechanisms that lead to the formation of these lesions," Awad said .
-
A nationwide longitudinal study by Professor Liu Min's team from the School of Public Health concludes that risk management can reduce maternal mortality in China
Time of Update: 2022-04-21
Figure Trends in Maternal Mortality and Proportion of High-Risk Pregnant Women in China Liu Min said that in the future, China should continue to implement the risk management strategy based on the five systems of maternal and child safety to ensure the realization of the United Nations Sustainable Development Goals and the "Healthy China 2030" plan by 2030 .
-
The research team of the Department of Infectious Medicine of Nanfang Hospital has achieved a series of research results on new markers of hepatitis B virus
Time of Update: 2022-04-21
Recently, a review "Circulating hepatitis B virus RNA: From biology to clinical applications" with Sun Jian from the Department of Infectious Medicine of Southern Hospital and two professors from the University of Pittsburgh, Guo Haitao, as the corresponding authors, was published online in Hepatology, an international authoritative journal in the field of gastrointestinal and liver diseases .
-
"Science" heavyweight: finally completed!
Time of Update: 2022-04-21
" After the T2T consortium sequenced the missing DNA, Altemose and his team used new techniques to find within the centromere where a large protein complex called the kinetochore holds onto the chromosome so that other machinery in the nucleus can Separate pairs of chromosomes .
-
Chinese scholars and foreign collaborators have made progress in the study of oxidized subarc asthenospheric mantle
Time of Update: 2022-04-21
Current research generally confirms that arc volcanic rocks in subduction zones are more oxidized than mid-ocean ridge basalts, but whether their oxidation comes from "mantle source" (material contribution of the subducted slab to the mantle wedge) or "crust source" (the influence of the crustal evolution process) ), is still controversial .
-
Shanghai Jiaotong University He Yawen's team has made important progress in the field of quorum sensing and salicylic acid signaling interaction of the plant pathogen Xanthomonas
Time of Update: 2022-04-21
Recently, "mBio", an international authoritative journal in the field of microbiology, published online a research article by Professor He Yawen's team from the School of Life Science and Technology, Shanghai Jiaotong University, "The plant defense signal salicylic acid increases the intracellular and extracellular pH of the phytopathogenic Xanthomonas spp.
-
Two Nature papers refute conventional wisdom: a new paradigm for DNA repair
Time of Update: 2022-04-21
Past research has identified an important search mechanism: transcription-coupled repair relies on RNA polymerase, a large protein machine (complex) that moves along DNA strands and reads instructions as they are transcribed Take the DNA code into the RNA molecule, which then directs the construction of the protein .
-
Shanghai Jiaotong University Xue Hongwei's research group revealed that auxin and brassinosterol synergistically regulate the development of rice leaf inclination angle
Time of Update: 2022-04-21
. Recently, Xue Hongwei's research group from Shanghai Modern Seed Industry Collaborative Innovation Center and School of Agriculture and Biology, Shanghai Jiaotong University published a research paper online in The Crop Journal entitled "Rice OsIAA6 interacts with OsARF1 and regulates leaf inclination", revealing that OsIAA6 interacts with OsIAA6- The OsARF1 module inhibits auxin signaling and is involved in the regulation of rice leaf inclination .
-
How 'Blood' 'Zinc' Works to Boost Immunity
Time of Update: 2022-04-21
Research has also shown that an experimental compound that mimics zinc's actions in this organ works even better than the natural mineral in promoting immune recovery and possible therapeutic potential in people receiving blood stem cell transplants as a treatment for advanced leukemia or another serious blood disorder .
-
New cancer-fighting substances found in soybean extract and kudzu
Time of Update: 2022-04-21
It should be noted that choline chloride and citric acid also have their own therapeutic properties and thus can enhance the effect of isoflavones on cancer cells," explains Abushanab say .
-
The team of Professor Zhu Ping of Shanghai Jiaotong University and his collaborators have made new progress in the design of mechanical invisibility cloaks
Time of Update: 2022-04-21
Figure 2 Mechanical stealth realization of various shapes of voidsIn order to verify the effectiveness of the method, the paper designed mechanical invisibility cloaks with different boundary conditions, cavity shapes and matrix microstructure > .
-
The research results of Zhang Huijie's team were published in the international authoritative journal Diabetes Care
Time of Update: 2022-04-21
Recently, the team of Zhang Huijie from the Department of Endocrinology and Metabolism of Nanfang Hospital of our school published an online publication entitled "Association of Serum 25-hydroxyvitamin D with Cardiovascular Outcomes and All-cause Mortality in Individuals with Prediabetes and Diabetes: Results from the UK Biobank Prospective Cohort Study", the corresponding author is Zhang Huijie, and the first author is Nanfang Hospital of Southern Medical University .
-
Where do red meat kiwis come from?
Time of Update: 2022-04-20
At present, multiple MYB transcription factors have been identified in kiwifruit with the potential to induce anthocyanin synthesis, but their real regulatory effects in kiwifruit fruit are not clear, and the molecular mechanism of red meat / red heart kiwifruit formation is also unclear .
-
New study explores link between psychedelics and consciousness
Time of Update: 2022-04-20
"This study shows that when beliefs change after a psychedelic experience, the tendency to ascribe consciousness to a different entity increases," said Sandeep Nayak, MD, PhD, Johns Hopkins Psychedelic and A postdoctoral researcher at the Center for Consciousness Research and one of the researchers involved in the study .
-
New Chinese Academy of Sciences-led study finds way to limit metastatic cancer growth
Time of Update: 2022-04-20
A research team led by Professor ZHU Tao from the University of Science and Technology of China (USTC), Chinese Academy of Sciences, published a study in the journal Nature Communications, revealing the role of phenotypic plasticity regulated by CSCs in metastatic colonization .
