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New Material: Get Faster, More Accurate COVID-19 Tests Now Without Poke Your Throat
Time of Update: 2022-04-22
In initial tests, the sensor detected SARS-COV-2 in saliva samples with 92 percent accuracy, comparable to PCR detection .
The sensor is based on large-area nanoimprint lithography, surface-enhanced Raman spectroscopy (SERS), and machine learning techniques .
Highly sensitive and ultra-rapid antigen-based detection of SARS-CoV-2 using nanomechanical sensor platform .
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Alzheimer's: Amyloid and tau are a dangerous combination
Time of Update: 2022-04-22
Our current findings suggest that this may indeed contribute to memory function in the early stages of the disease," said brain researcher Emrah Düzel, an equine Spokesman for the DZNE website in the city of Gedeburg and director of the Institute for Cognitive Neurology and Dementia at Otter von Glick University in Magdeburg .
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Nature Metabolism: Appetite genes control children's growth
Time of Update: 2022-04-22
These findings provide a better understanding of the mechanisms that control appetite and energy metabolism early on, and could help us find better treatments for obesity in adolescence and adulthood .
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The team of Tian Ying and Gao Yu from the School of Public Health of Environment International found that NEOs were violent during pregnancy...
Time of Update: 2022-04-22
The paper (to be published in May 163) explores the relationship between NEOs exposure during pregnancy and birth outcomes and the potential mediating effect of oxidative stress .
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New hypoglycemic drug: Save insulin-producing cells in diabetics
Time of Update: 2022-04-22
Erwin Ilegems, first author of the new study and senior researcher at the Department of Molecular Medicine and Surgery, Karolinska Institutet, said: "In diabetics, beta cells are challenged to produce large amounts of insulin .
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Study reveals decisive role of PDK1 enzyme in acute myeloid leukemia
Time of Update: 2022-04-22
Treatment of acute myeloid leukemia (AML) remains difficult because of high genetic heterogeneity not only between patients, but also between subclonal populations of cancer cells within the same individual .
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PNAS: Cell division in embryos is not a typical symmetry phenomenon
Time of Update: 2022-04-22
Their latest findings, published in the Proceedings of the National Academy of Sciences (PNAS), could change the understanding of one specific aspect of cell division and open the door to further research into how cell division plays a role in the viability of embryos, even human embryos.
In one of our experiments, Lia discovered that something unusual happens during cell division .
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Right or wrong?
Time of Update: 2022-04-22
Researchers at The University of Texas MD Anderson Cancer Center have discovered that two distinct types of cancer-associated fibroblasts (CAFs) accumulate in the pancreatic cancer microenvironment and play opposite roles, either promoting or inhibiting pancreatic cancer progression.
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Shanghai Jiaotong University Li Can and Cui Daxiang's research group has made new progress in the field of nano-drug delivery carriers
Time of Update: 2022-04-22
Li Can's research group from Bio-X Institute of Shanghai Jiaotong University and Cui Daxiang's research group from School of Electronic Information and Electrical Engineering cooperated to publish a cover article in the internationally renowned academic journal Nanoscale, "Engineered mesenchymal stem cell-derived exosomes with high CXCR4 levels for targeted siRNA gene therapy against cancer", and was included in the "2022 Nanoscale HOT Article Collection" series .
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Nature sub-journal: This method can shorten the culture time of CAR T cells
Time of Update: 2022-04-22
"While traditional manufacturing methods for making CAR-T cells take days to weeks, there is still a need to reduce the time and cost of producing these complex therapies," Milone said.
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BIOPIC Zhang Zemin/Ren Xianwen's research group and collaborators analyze the potential influencing factors of tumor microenvironment formation
Time of Update: 2022-04-22
Unlike cross-cancer analysis, the tumor metastasis process provides researchers with a unique system to unravel the effects of niche and malignancy on TME, since metastatic tumors originate from the same individual's primary tumor, collecting different tumor sites from patients with metastases can Help researchers to parse the TME formed by tumor cells of the same origin in different organs .
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eLife Surprising Discovery: Epigenetic-Accelerated Aging Causes Bowel Cancer
Time of Update: 2022-04-22
The acceleration, as measured by a DNA methylation-based predictor of age known as the epigenetic clock, is associated with several adverse health outcomes, including cancer .
The team compared four established epigenetic clocks used to measure biological aging and their genetically predicted links to a range of cancer types .
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New progress in identification of tick-derived promoters and research on tick cell line transfection systems
Time of Update: 2022-04-22
Establishing a plasmid transfection method for tick cell lines and efficiently driving the expression of exogenous proteins is of great significance for the study of the interaction mechanism between tick-borne viruses and key proteins and factors in tick cells, and for analyzing the infection and replication mechanism of viruses in tick cells .
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'eLife' Egg cells have a backup plan
Time of Update: 2022-04-22
Sadie Wignall of Northwestern University, who led the study, said: "Before our work, certain proteins were thought to be necessary for cell division .
To understand why egg cells are more prone to errors, Wignall studied a football-shaped structure called the spindle, which organizes genetic material before egg cells divide .
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Lung disease-causing bacteria live on red blood cells
Time of Update: 2022-04-22
Now, a new study by Hiroshima University scientists has found that mycobacteria are associated with red blood cells at the site of infection in the lungs, an interaction that has remained undiscovered by science in the 140 years since the discovery of the microbe that causes tuberculosis .
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PNAS identifies potential therapeutic window for ALS
Time of Update: 2022-04-22
In this study, his team showed that the drug tonabersat, originally used to treat migraine and epilepsy, blocked astrocyte-induced motor neuron death in human ALS stem cell lines and animal models .
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The team of Professor Ma Lizhuang of Shanghai Jiaotong University published 14 high-level papers in CVPR 2022
Time of Update: 2022-04-22
This paper proposes a new large-scale knowledge base Oakink, which aims to recognize and understand the interaction behavior of objects through visual information .
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10-second video can predict blood cancer recurrence
Time of Update: 2022-04-22
In a previous study involving non-invasive microscopy and graft-versus-host disease, researchers stumbled upon a link between higher white blood cell activity and cancer recurrence .
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Positive Phase 2 Clinical Results of LAG-3 Therapy for Non-Small Cell Lung Cancer
Time of Update: 2022-04-22
"References:[1] Immutep's efti in combination with MSD's pembrolizumab shows encouraging antitumor activity in difficult to treat 2nd line metastatic lung cancer patients.
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Expanding the target range of CRISPR/Cas systems
Time of Update: 2022-04-22
Professor Basil Hubbard University of Toronto researchers have created a genome-editing technique that allows small changes in target DNA but retains local specificity, which could help realize the potential of CRISPR/Cas-based gene therapy and pathogen diagnosis .
