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With the help of high-precision tweezers, scientists take a closer look at the pseudopodia of cancer cells
Time of Update: 2022-04-24
With the help of the world's best tweezers, a team of researchers at the University of Copenhagen has uncovered the fundamental mechanisms of all living cells that help them explore their surroundings and even invade tissues .
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Local gene therapy in vivo for recessive dystrophic epidermolysis bullosa
Time of Update: 2022-04-24
Here, we evaluated bermagene geperpavec (B-VEC), an engineered, non-replicating herpes simplex virus type 1 (HSV-1)-containing COL7A1 vector, in the treatment of RDEB skin .
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Yu Hongjie's research group has made progress in the field of genetic monitoring and data sharing of the new coronavirus
Time of Update: 2022-04-24
To this end, Yu Hongjie's research group conducted a study to construct a series of evaluation indicators by collecting genetic surveillance programs from countries around the world, officially reported variant strain data, and gene sequencing data on public platforms to analyze SARS-CoV-2 The heterogeneity of genetic surveillance, the character and quality of genetic sequencing data, the degree of sharing of genetic data, and the discovery and global dissemination of variants of concern (VOCs) .
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"Nature" Potential femoral nasal spray can prevent and treat COVID-19
Time of Update: 2022-04-24
A newly discovered small molecule can be sprayed into people's noses to prevent disease before exposure to COVID-19, according to a study of mice (K18-human ACE2 transgenic mice) led by researchers at Cornell University.
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Nature sub-journal: Controlling cells for personalized cancer treatment
Time of Update: 2022-04-24
"The separation of pairs of particles or cells has been a major goal in the field of acoustic manipulation for many years," said Tony Jun Huang, the William Bevin Distinguished Professor of Mechanical Engineering and Materials Science at Duke University .
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South China Botanical Garden "an immunomodulatory active peptide and its preparation method and application", "an immunomodulatory active hexapeptide and its preparation method and application", "an immunomodulatory active hepteptide and its preparation method and application" were invented patent
Time of Update: 2022-04-24
The fractions eluted from a specific concentration of ethanol solution are collected, concentrated and dried to obtain the target immunomodulatory active peptide, immunomodulatory active hexapeptide, and immunomodulatory activity.
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Shanghai Jiaotong University Zhang Xueqing's research group develops a biomimetic nano-delivery system targeting brain tumors
Time of Update: 2022-04-24
The researchers further studied in the orthotopic glioma mouse model and found that the modification of the penetrating peptide RGE significantly improved the efficiency of HFn nanocarriers infiltrating deep tumors and targeting tumor cells, and did not affect the high efficiency of HFn nanoparticles across the BBB.
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Assessing the invasive and metastatic potential of cancer cells from tissue sections
Time of Update: 2022-04-24
Using this approach, the team found that by agitating a solution containing molecular probes that bind to Rac/Cdc42 activated on cancer tissue sections, they were able to rapidly and definitively assess colon cancer cell motility and invasive capacity .
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The team of Professor Zhang Wenming of Shanghai Jiaotong University has made a new breakthrough in the piezoelectric dynamics of human arterial pulse
Time of Update: 2022-04-24
The new method of electrodynamic analysis reveals the perfect mapping relationship between piezoelectric pulse wave and human blood pressure wave, breaks through the key technical bottleneck of flexible MEMS piezoelectric sensing in continuous blood pressure monitoring, and provides a solid foundation for the development of wearable blood pressure monitoring.
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Penn Medicine Study Finds Inflammation Not Always Linked to Depression
Time of Update: 2022-04-23
"Inflammatory disorders do contribute to depression, but our findings suggest that a subset of older adults with depression do not have elevated levels of inflammation, " says McClure, professor of psychiatry and behavioral research at the Perelman School of Medicine at the University of Pennsylvania.
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Biopsy (biopsy) a thing of the past
Time of Update: 2022-04-23
A new paper published today in the journal Nature Biomedical Engineering describes MediSCAPE, a high-speed 3D microscope capable of capturing images of tissue structure that can guide surgeons to navigate tumors and their borders without The tissue needs to be removed and the pathology results awaited .
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More than $6 billion to develop IgM antibody therapy, Sanofi reaches cooperation
Time of Update: 2022-04-23
Today, Sanofi and IGM Biosciences announced a research and development collaboration to develop agonists against three oncology targets and three immunology/inflammation targets using IGM Biosciences' unique IgM antibody technology platform .
"References:[1] Sanofi and IGM Biosciences Announce Collaboration Agreement for Oncology, Immunology and Inflammation Targets.
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Brain-computer interface helps paralyzed patients use computers for daily tasks
Time of Update: 2022-04-23
Study author Bruce Campbell, MD, MPhil, MD, University of Melbourne, Australia, and member of the American Academy of Neurology, said: "People with ALS eventually lose the ability to move their limbs, leaving them unable to operate devices such as cell phones or computers .
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Genetic risk for asthma stems from changes in airway cells, study finds
Time of Update: 2022-04-23
The first step in TWAS research is to build models to predict how a person's genes function in a particular tissue, based solely on their genetic map .
This allowed them to test whether genetically altered airway gene function was associated with asthma risk .
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Antibody diversity decreases with age
Time of Update: 2022-04-23
A team of researchers led by Dario Ricardo Valenzano investigated whether the immune system of short-lived killifish ages .
"If different antibodies decrease with age, this could lead to a decrease in the ability to respond to infection .
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Liquid biopsy provides new tool for detecting recurrent breast cancer and monitoring its progression
Time of Update: 2022-04-23
Professor Arto Mannermaa from the University of Eastern Finland explained: "By monitoring cancer mutations detected from cell-free DNA, not only recurrent breast cancer can be detected, but also mutations relevant to treatment planning can be identified to support decision-making by medical professionals .
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Photoacoustics for high-precision neuromodulation
Time of Update: 2022-04-23
Complementary to fiber-based photoacoustic emission devices, biocompatible photoacoustic membranes can serve as new neural interfaces that provide a variety of functions, from photoacoustic stimulation to structural support and growth guidance .
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Different SARS-CoV-2 virus variants cause different long-term COVID symptoms
Time of Update: 2022-04-23
A new study presented at this year's European Congress of Clinical Microbiology and Infectious Diseases in Lisbon, Portugal, 23-26 April 2022 suggests that symptoms associated with long COVID may differ among people infected with different variants .
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Neuron releases cellular atlas of trigeminal ganglia, promising to reveal therapeutic targets for migraine
Time of Update: 2022-04-23
Recently, researchers at Brigham and Women's Hospital and Massachusetts General Hospital mapped the cells of the human and mouse trigeminal ganglia, analyzing the genes expressed by each TG cell type at single-cell resolution .
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New treatment for rare blood cancer
Time of Update: 2022-04-23
Gotlib advised Worthen to participate in a phase 1 clinical trial of a drug he leads called avapritinib, which works similarly to midostat but is unlikely to cause serious side effects because it only targets the KIT protein .
