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Nature sub-journal: A novel method of mRNA delivery using extracellular vesicles
Time of Update: 2023-02-01
Intradermally delivered mRNAencapsulating extracellular vesicles for collagen-replacement therapy Dr. Betty KimSource: University of Texas Anderson Cancer CenterA team of researchers led by the University of Texas MD Anderson Cancer Center has developed a novel messenger RNA (mRNA) delivery system using extracellular vesicles (ev).
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Nat Aging: Scientists have the potential to map senescent cells in the body and their effects on aging and health
Time of Update: 2023-02-01
1038/s43587-022-00326-5 Recently, a study entitled "NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health" published in the international journal Nature Aging, Scientists from Jackson Laboratory and other institutions in the United States have drawn a map of senescent cells and their impact on aging and human health through research.
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Detectable 10 years before Alzheimer's disease symptoms appear!
Time of Update: 2023-02-01
Alzheimer's disease begins decades before any symptoms, such as memory loss, begin to manifest. Therefore, early diagnosis increases the chances of slowing the disease with medication. A new study on
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Shenzhen Bay Laboratory has made a series of important progress in esophageal squamous cell carcinoma research
Time of Update: 2023-02-01
Esophageal cancer is one of the world's most common malignant tumors, China's esophageal cancer incidence and mortality are ranked first in the world, the latest statistics show that in China every y
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The research group of Jaehyung Ju, a teacher at JI at Shanghai Jiaotong University, proposed the design of magneto-thermal reprogrammable mechanical metamaterials
Time of Update: 2023-02-01
Recently, the team of Jaehyung Ju, a teacher at JI Shanghai Jiao Tong University, published a scientific paper entitled "Magneto-Thermomechanically Reprogrammable Mechanical Metamaterials" in Advanced Materials (impact factor 32.
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Science: Infections in hospitalized patients may be caused by their own bacteria
Time of Update: 2023-02-01
Through studies of mice, the researchers found that urinary tract infections (UTIs) occurred even after a sterile catheter was inserted into the urethra, even if no bacteria were detected in the bladder beforehand.
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Aging: Studying combinations of genetic mutations may hold promise to uncover specific biomarkers of Alzheimer's disease in humans
Time of Update: 2023-02-01
Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers, Aging (2022).
Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers, Aging (2022).
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The protein science research team worked with the rapeseed team to analyze plant-specific phospholipid hydrolases...
Time of Update: 2023-02-01
Link to the paper: Review: Liu Zhu Guo Liang Nanhu News Network News (correspondent Fan Ruyi) Recently, Hubei Hongshan Laboratory, the National Key Laboratory of Crop Genetic Improvement, the protein science research team and the rapeseed team published an online report entitled "Insights into themechanism of phospholipid hydrolysis by plant non-specific" in Nature Communications phospholipase C".
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Scholars from the Chinese Academy of Sciences published an article today in Nature: revealing the structural basis of the inherent transcription termination of bacteria
Time of Update: 2023-02-01
On January 12, 2023, Yu Zhang's research team from the Key Laboratory of Synthetic Biology, Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, and the team of Robert Land
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The South China Botanical Garden used ecogenomics methods to predict the response of forest tree species to climate change
Time of Update: 2023-02-01
Wang Baosheng's research group of researcher Wang Baosheng of the South China Botanical Garden of the Chinese Academy of Sciences took Quercus acutissima, a species of quercus in China, which is widely distributed in China, as the research object, based on population genetics and ecological genomics theory, through genetics Ecological factor modelling methods explore the resilience of the species to future climatic conditions.
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Researcher Fengyan Bai of the Institute of Microbiology received the Johanna Westerdijk Award
Time of Update: 2023-02-01
The award is a scientific prize selected and presented by the Westerdijk Institute for Fungal Biodiversity (formerly CBS) of the Royal Netherlands Academy of Sciences (KNAW) to recognize outstanding contributions to the preservation of CBS cultures and outstanding achievements in mycological research.
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Insulin tablets go one step further
Time of Update: 2023-02-01
Micromotor Based Mini-Tablet for Oral Delivery of Insulin As shown, chemical "micromotors" can efficiently deliver insulin to rats without injection.
Micromotor Based Mini-Tablet for Oral Delivery of Insulin As shown, chemical "micromotors" can efficiently deliver insulin to rats without injection.
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Progress in predicting bacterial diversity in the metabolic model of Nanjing soil
Time of Update: 2023-02-01
Paper link Figure 1 Theoretical framework of pH and temperature two-factor metabolic model Figure 2 Validation of two-factor models at different levels Soil biodiversity is extremely complex, often containing billions of organisms in small amounts of soil, including soil microorganisms (bacteria, fungi and protists) and soil fauna (nematodes).
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Molecular mechanisms by which nutrients induce disease resistance in plants
Time of Update: 2023-02-01
1094/PHYTO-02-22-0052-RRupali Gupta, Meirav Leibman-Markus, Gautam Anand, Dalia Rav-David, Uri Yermiyahu, Yigal Elad, Maya Bar. Nutrient Elements Promote Disease Resistance in Tomato by Differentially Activating Immune Pathways.
1094/PHYTO-02-22-0052-RRupali Gupta, Meirav Leibman-Markus, Gautam Anand, Dalia Rav-David, Uri Yermiyahu, Yigal Elad, Maya Bar. Nutrient Elements Promote Disease Resistance in Tomato by Differentially Activating Immune Pathways.
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Nature Cancer: The level of inflammation is related to the severity of blood cancer
Time of Update: 2023-02-01
Researchers at NYU Langone Health Center and its Cancer Center used bone marrow samples from 20 adults and 22 children with the deadly disease to score each patient's level of inflammation.
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Why do humans age? The answer may have a lot to do with mitochondria
Time of Update: 2023-02-01
OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases It is thought that mitochondrial defects (impairs the conversion of food sources into usable energy) force cells to slow down their metabolic rate in an effort to conserve energy.
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The Slit2 signaling pathway stimulates the growth of Ewing's sarcoma
Time of Update: 2023-02-01
Their findings reveal a novel role in stimulating the growth of Ewing sarcoma by the Slit2 signaling pathway and suggest that the pathway can be targeted for therapy.
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Hu Junjie's research group collaborated to develop a small molecule fusion agonist to repair mitochondrial damage
Time of Update: 2023-02-01
On January 12, 2023, Hu Junjie's team from the Institute of Biophysics, Chinese Academy of Sciences, Chen Bai's team from Nankai University and Hao Xiaojiang's team from the Kunming Institute of Botany, Chinese Academy of Sciences presented a presentation in Nature Chemical Biology The co-published article titled "Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction" reports S89, a small molecule compound that specifically activates MFN1 and repairs multiclass mitochondrial damage.
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The Pesticide Toxicology and Pest Resistance team has made new progress in the field of pest resistance
Time of Update: 2023-02-01
Microbiome variation driven by abiotic environmental factors shapes the detoxification gene expression pattern of brown planthoppers, which in turn affects host insecticide resistance variation Based on the major needs of green, high-quality and safe rice production in China, the research team carried out a series of studies on the resistance of brown planthopper, an important rice pest.
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THF-II riboswitch recognizes ligands and regulates structural mechanisms of gene translation
Time of Update: 2023-02-01
1093/nar/gkac1257 Tetrahydrofolate (THF) and its derivatives, collectively known as folic acid, are coenzymes of the one-carbon transferase system in the body, which can be used as a carrier of one carbon group to participate in the synthesis of a variety of biologically active substances, and are therefore essential in the normal cellular metabolism of almost all life forms.
