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Breakthrough in development of oral insulin tablets
Time of Update: 2022-09-07
Professor Anubhav Pratap-Singh said: "These exciting results show that we are on the right track in developing an insulin formulation that no longer requires injections before each meal, which will improve the The quality of life and mental health of people with diabetes .
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Researcher Wang Jianwei from the School of Physics won the 2022 Asia-Pacific Federation of Physical Societies-Asia-Pacific Center for Theoretical Physics "Yang Zhenning Award"
Time of Update: 2022-09-07
The winner of the "Yang Zhenning Award" in 2022, with Wang Jianwei in the middleWang Jianwei is one of the earliest scholars in the world to carry out interdisciplinary research on integrated optics, quantum physics, and quantum information science.
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Cancer Cell Review: Technological Advances in Cancer Treatment
Time of Update: 2022-09-07
Rubin, Director of the Biomedical Research Department (DBMR) and the Center for Precision Medicine (BCPM) at the University of Bern summarize and review the latest advances in multi-omics tumor analysis .
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Nature Genetics: To treat childhood leukemia, scientists map mutation roadmap
Time of Update: 2022-09-07
Because of the size of this study, we were able to Identifying many new genes not previously associated with leukemia or cancer and showing the cellular pathways they are involved in .
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Sci Rep: A method for direct measurement of skeletal muscle myotube strength
Time of Update: 2022-09-07
Image credit: Tokyo Metropolitan UniversityResearchers at Tokyo Metropolitan University have developed a method to characterize the forces generated by contracting myotubes, the precursors of skeletal muscle fibers, combining electrical stimulation and analysis of wrinkles on silicone substrates .
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How does the gut help drive COVID-19?
Time of Update: 2022-09-07
"Single-cell gene expression links SARS-CoV-2 infection and gut serotonin New findings from Flinders University demonstrate the molecular link between COVID-19 and serotonergic cells in the gut .
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Synergistic effects of BCL-2 family inhibitors contribute to selective clearance of senescent cells
Time of Update: 2022-09-07
"article titleSynergistic action of BCL-2 family inhibitors facilitates selective clearance of senescent cells Experimental setup and data analysisCellular senescence, a complex cellular response to stress characterized by the arrest of cell cycle progression, is a contributing factor to aging, according to a new research paper published in Aging .
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Where did the "sense of rhythm" come from?
Time of Update: 2022-09-07
Neuroscientists at the Massachusetts Institute of Technology (MIT) have now discovered a neuronal property and mechanism in these circuits: an oscillator that controls the rhythmic back-and-forth swing of mouse tactile tentacles .
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New treatment may lead to more donor lungs
Time of Update: 2022-09-07
Sandra Lindstedt, adjunct professor at Lund University, said: "Our findings suggest that a certain treatment could help us use a larger portion of the donor lung, with improved outcomes two days after surgery .
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Signal transduction pathways from wound healing to regeneration
Time of Update: 2022-09-07
Injury-induced MAPK activation triggers body axis formation in Hydra by default Wnt signaling The phenomenon of regeneration was discovered in freshwater polyps more than 200 years ago .
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Lupus immunomodulation research based on large cohort and single-cell RNA sequencing technology
Time of Update: 2022-09-07
To accompany the lupus advocacy, we share here two innovative studies that have brought new insights into systemic lupus erythematosus (SLE) to understand genomic differences in circulating immune cells and cell-type-specific genes Express the relationship between features .
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Coupling mechanism of biological clock genes regulating environmental temperature and plant growth
Time of Update: 2022-09-07
This paper reveals that the transcriptional repressor RVE5 (REVEILLE5) regulates the expression of ELF4 (EARLY FLOWERING 4) by competing with the transcriptional repressor CCA1 (CIRCADIAN CLOCK ASSOCIATED 1), which has stronger transcriptional repression activity, at mild and high temperature, thereby increasing the downstream effects of ELF4 on the Inhibition of growth-related genes, inhibiting plant overgrowth at high temperatures .
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Huang Tao's research group reveals the relationship between social risk score, genetics, healthy lifestyle and the risk of type 2 diabetes
Time of Update: 2022-09-07
46), a well-known journal in the field of endocrinology and metabolism, published online a research paper by Huang Tao's group from the Department of Epidemiology and Health Statistics, School of Public Health, Peking University, entitled "Associations of polysocial risk score, lifestyle and genetic factors with incident" type 2 diabetes: a prospective cohort study", this paper revealed the relationship between the polysocial risk score (polysocial risk score), lifestyle, genetic risk and the risk of developing type 2 diabetes .
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Nature Medicine of East China Normal University reports the world's first clinical results of CRISPR gene editing in children with β0/β0 severe thalassaemia
Time of Update: 2022-09-07
The trial transplanted gene-edited autologous hematopoietic stem progenitor cells (HSPCs) into two pediatric patients, one with the β0/β0 genotype classified as the most severe type of TDT; the other treated with Also belongs to TDT .
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PNAS: Chromosome movement linked to injury response, ability to repair itself
Time of Update: 2022-09-07
A multidisciplinary team of researchers at Indiana University has discovered that the movement of chromatin, the substance that makes up DNA, can help promote efficient repair of DNA damage in the nucleus of human cells—a discovery that could lead to improved cancer diagnosis and treatment .
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Nature Professor Ma Jinbiao's research results published in the main journal of "Nature"
Time of Update: 2022-09-07
The Dicer-2–Loqs-PD complex binds the complete cycle of ATP-dependent processing of double-stranded RNA to generate siRNA .
The Dicer-2–Loqs-PD complex binds the complete cycle of ATP-dependent processing of double-stranded RNA to generate siRNA .
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Nature Medicine Stem Cell Gene Therapy Shows Promise in ALS Treatment Trial
Time of Update: 2022-09-07
Transplantation of human neural progenitor cells secreting GDNF into the spinal cord of patients with ALS: a phase 1/2a trial Cedars-Sinai researchers have developed an investigational therapy that uses Sertoli cells and a protective protein that can cross the blood-brain barrier .
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Jiang Ying's group from the School of Physics uses a new scanning probe technology to greatly improve the coherence of solid-state qubits
Time of Update: 2022-09-07
Microscope system, a new technology for controllable manipulation of diamond near-surface electron spin library has been developed, which greatly improves the coherence of shallow solid-state qubits (coherence time T2 can be extended by up to 20 times), which is expected to break through the application bottleneck in the field of quantum sensing.
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Cell's unexpected new discovery: It turns out that this "near-death experience" makes cancer cells worse
Time of Update: 2022-09-07
article titleSublethal cytochrome c release generates drug-tolerant persister cells Dr. Halime Kalkavan and Dr. Doug GreenSource: Courtesy of St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospital have discovered how some cancer cells cheat treatment-induced cell death .
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A new strategy to treat Huntington's disease
Time of Update: 2022-09-07
154108 The study, co-authored by Jin Jiongzhu (transliteration), was published in the online edition of the Journal of Clinical Investigation Insights on August 9, 2022, with the title "A pathogenic proteolysis-resistant huntingtin isoform induced by an antisense oligonucleotide maintains huntingtin function.