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Fungal food is here!
Time of Update: 2022-09-08
"As well as advising startups, the researchers at Nanyang Technological University's FST project also hope to develop their products to further improve their nutritional content while reducing food waste .
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Japanese scholars have constructed the first mouse model carrying mitochondrial tRNALeu mutations
Time of Update: 2022-09-08
Recently, a team of researchers at the University of Tsukuba in Japan constructed the first mouse model carrying disease-associated mitochondrial tRNA Leu mutations, and showed that the resulting disease was caused by misprocessing of RNA.
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[Research News] The team of Professor Chen Junwei from the School of Life of Huazhong University of Science and Technology revealed that original targeted anticancer drugs induce apoptosis and inhibition of malignant tumor stem cells...
Time of Update: 2022-09-08
202203173 On August 28, Advanced Science, an international authoritative journal, published an online article entitled "Synthetic "retinoid kills drug-resistant cancer stem cells via inducing RARγ translocation mediated tension reduction and chromatin decondensation", jointly revealing that the original targeted anticancer drug-a novel retinoic acid analog WYC-209 efficiently induces the apoptosis of malignant tumor stem cells and inhibits cancer New Mechanobiological Mechanisms of Metastasis .
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Cell: Sugar destroys the gut microbiome and eliminates protection against obesity and diabetes
Time of Update: 2022-09-08
"Article titleMicrobiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome The findings, published in the journal Cell, suggest that diet is important, but an optimal microbiome is just as important for preventing metabolic syndrome, diabetes, and obesity.
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Nature Aging: Is there really a drug that can make you "rejuvenate", can you believe it?
Time of Update: 2022-09-08
”Article titleLong-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy Figure: Rapamycin is currently the most promising anti-aging drug.
”Article titleLong-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy Figure: Rapamycin is currently the most promising anti-aging drug.
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A new third mechanism for polysaccharide output
Time of Update: 2022-09-08
Gram-negative bacteria include some of the most destructive human pathogens, and there are only two known polysaccharide output mechanisms: the outer membrane OPX protein (in the so-called Wzx/Wzy- and ABC transporter-dependent pathways) and the outer membrane β barrel protein (in the so-called synthase-dependent pathway).
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Can dogs also suffer from Alzheimer's disease? The latest study says the risk increases year on year with the age of dogs
Time of Update: 2022-09-08
BEIJING, Aug. 26 (Xinhua) -- A recent veterinary research paper published in Science Reports, an open access academic journal owned by Springer Nature, argues that for dogs over 10 years old, their relative risk of developing Canine Cognitive Dysfunction (CCD), commonly known as dog dementia, will increase by more than 50% year by year.
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The location and cause of protein malfunction in Parkinson's disease
Time of Update: 2022-09-08
Sonia Gandhi, lead author and senior group leader at Crick University and Professor of Neurology at UCL's Queen Square Institute of Neurology, said: "Great progress has been made in understanding protein misfolding, but the main challenge is research The first stage of this process in human cells .
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New therapeutic targets for triple-negative breast cancer were discovered
Time of Update: 2022-09-08
The researchers then experimented with triple-negative breast cancer cell lines to determine whether an increase in TLX expression reduces the cancer's typical characteristics: tumor growth, migration, invasion, and metastasis.
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Large-scale sequencing efforts link the new gene to the risk of Crohn's disease
Time of Update: 2022-09-08
Genome-wide association studies (GWAS) have revealed common genomic variants and regions, or loci, in Crohn's disease, but most variants are located in regions of the genome that do not code for proteins, making it difficult for scientists to study their function and propose strong therapeutic hypotheses.
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"PNAS" Drunk once, can permanently change brain nerves
Time of Update: 2022-09-08
The study, "Single-dose ethanol intoxication causes acute and long-lasting neuronal changes in the brain," was published in the Proceedings of the National Academy of Sciences (PNAS) .
Single-dose ethanol intoxication causes acute and lasting neuronal changes in the brain.
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eLife: Young people with genetic risk of mental illness have different brain activity when they sleep
Time of Update: 2022-09-08
They measured the correlation between sleep EEG patterns and psychiatric symptoms, as well as performance on a recollection test the next morning.
They measured the correlation between sleep EEG patterns and psychiatric symptoms, as well as performance on a recollection test the next morning.
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Genetically boosting neurons restores memory in Alzheimer's mice
Time of Update: 2022-09-08
"However, the role of newly formed neurons in memory formation, and whether deficits in neurogenesis contribute to AD-related cognitive impairment, remains unclear," said Orly Lazarov, professor of anatomy and cell biology at the University of Illinois at Chicago School of Medicine.
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The scientific research team of the Institute of Microbiology reveals the material basis and molecular mechanism of Qilian Mountain's characteristic mushroom polysaccharide to improve intestinal flora and weight loss
Time of Update: 2022-09-08
The results showed that the isolated polysaccharide could not only significantly reduce obesity symptoms in high-fat diet-induced obese (DIO) mice, but also regulate the structure and function of gut microbiota, enrich Bacteroides intestinalis and Lactobacillus johnsonii, and increase plasma and The content of secondary bile acids, especially lithocholic acid (LCA) and deoxycholic acid (DCA) in feces, promotes the body's heat production and enhances the body's energy consumption .
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New labeling method for "exosomes"
Time of Update: 2022-09-08
He was the corresponding author of a study in the Journal of Extracellular Vesicles, detailing a labeling technique he and his research team developed to analyze exosome content for any particular cell type to better understand their role in health and disease.
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The new ALS blood test promises rapid diagnosis
Time of Update: 2022-09-08
Article titlemiRNA extracted from extracellular vesicles is a robust biomarker of Amyotrophic Lateral Sclerosis Image: Dr. Sandra Barnack prepares microRNA analysis of blood samples from ALS patients in the Brain Chemistry Laboratory.
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Plants also develop mitochondrial genomic mutations, but they can be repaired and are not passed on to future generations
Time of Update: 2022-09-08
How do plants experience mitochondrial mutations?Amanda Broz, a research scientist in the lab of Dan Sloan, an associate professor in the Department of Biology, led a study recently published in the Proceedings of the National Academy of Sciences that revealed how plant mitochondrial genomes mutate, though rarely happen.
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Science Advances New Breakthrough: A New Method for Rapid and Efficient Production of Human Immune Cells
Time of Update: 2022-09-08
Article titleDLL4 and VCAM1 enhance the emergence of T cell–competent hematopoietic progenitors from human pluripotent stem cells A team of researchers at the University of British Columbia has developed a new, fast, and efficient way to produce cancer-fighting immune cells in the lab.
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Can we reverse the memory decline caused by age? Scientists say yes
Time of Update: 2022-09-08
Article titleLong-lasting, dissociable improvements in working memory and long-term memory in older adults with repetitive neuromodulation Image: A researcher performs a stimulus treatment through a hat.
Article titleLong-lasting, dissociable improvements in working memory and long-term memory in older adults with repetitive neuromodulation Image: A researcher performs a stimulus treatment through a hat.
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New research data from Nilapali are released, suggesting more possibilities in advanced ovarian cancer
Time of Update: 2022-09-08
Patients with advanced ovarian cancer avoid excessive fear of recurrence affecting current treatment In fact, lower levels of fear of cancer recurrence are considered to be normal emotional responses, which can help patients monitor and care for their own condition and improve their vigilance against cancer recurrence.
