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$3.16 million in funding for the development of cancer immunotherapy drugs
Time of Update: 2022-09-09
16 million from the National Cancer Institute to develop a drug that could boost the immune system response of cancer patients and destroy tumor cells.
16 million from the National Cancer Institute to develop a drug that could boost the immune system response of cancer patients and destroy tumor cells.
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New preclinical models could accelerate research into thymic cancer
Time of Update: 2022-09-09
, professor of medicine and associate director of clinical research at Sandra and Edward Meyer Cancer Center at Weill Cornell School of Medicine, and his colleagues described a genetically engineered mouse model in which animal thymic epithelial cells contain a genetic variant called GTF2I L424H, the most common mutation in thymic cancer.
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Nature Metabolism: Control of diet in areas other than the brain!
Time of Update: 2022-09-09
The new review paper, written by lead authors Wenwen Cheng, Dr. Myers, Pers, and their colleagues, combined these findings with other recent findings to build a new model of neural circuits in the brainstem and how they control food intake and nausea.
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Blood of China University of Science and Technology: Mechanism of early recurrence of AML after allo-HSCT
Time of Update: 2022-09-09
A few days ago, the research group of Professor Wei Haiming from the Department of Life Sciences and Medicine of the Chinese University of Science and Technology cooperated with the team of Professor Sun Zimin and Professor Zhu Xiaoyu from the Department of Hematology of the First Affiliated Hospital to investigate the relapse mechanism and intervention of acute myeloid leukemia (AML) after allogeneic hematopoietic stem cell transplantation (allo-HSCT).
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Cell Sub-Journal: It turns out that there is also a "helpful" brain area!
Time of Update: 2022-09-09
Article titleDistinct neural representations for prosocial and self-benefitting effort Scientists at the University of Birmingham and the University of Oxford have identified an area of the brain that is specifically responsible for helping others.
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The Hong Kong University of Science and Technology has discovered a protein that can be used to treat Alzheimer's disease
Time of Update: 2022-09-09
Article titleAn IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease Figure: This figure shows how an increase in the level of sST2 in AD impairs microglia clearance of amyloid pathology: an increase in the level of sST2 protein (1) in the blood enters the brain; This bait receptor blocks the normal signaling of IL-33 stimulation in microglia (2).
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A new way to remove toxic waste from the brain
Time of Update: 2022-09-09
Researchers at Washington University School of Medicine in St. Louis have discovered a new drug pathway that can increase the amount of longwater channel protein 4 near blood vessels and increase the clearance of waste products from the brain.
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Root pressure for recovery of plants rust-colored spiderwort after dehydration...
Time of Update: 2022-09-09
To this end, Associate Researcher Fu Peili and Researcher Fan Zexin cooperated with researchers from Anhui Normal University, Yunnan University, University of Western Australia and the University of Maine, combining field sampling and potted plants, to further study the effect of rust-colored spiderwort in Changes in parameters such as leaf gas exchange, leaf water content, leaf hydraulic conductance, and root pressure during drought and post-drought rehydration .
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No need for bacterial culture, a new method for rapid detection of multiple bacteria in 1 hour
Time of Update: 2022-09-09
To meet this need, a research team led by Professor Hiroshi Shiigi of the Graduate School of Engineering of Osaka Metropolitan University used the optical properties of organometal NHs – a composite material composed of polyaniline particles that encapsulates a large number of metal nanoparticles – to quickly and simultaneously identify intestinal hemorrhagic Escherichia coli (E.
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eLife: The gut microbiome is influenced by host genes
Time of Update: 2022-09-09
"Article titleKey features of the genetic architecture and evolution of host-microbe interactions revealed by high-resolution genetic mapping of the mucosa-associated gut microbiome in hybrid mice Scientists say your gut microbiome, the bacterial community that lives in your digestive system, is influenced not only by your diet and environment, but also by your genes.
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The oversized action of nanopores
Time of Update: 2022-09-09
Research from washington University St. Louis' McKelvey School of Engineering suggests that when these materials are soaked in liquids, the chemistry inside tiny pores called nanopores can be very different from the chemistry in the overall solution.
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A new study suggests that the plant immune system can adapt to stressors in inanimate environments
Time of Update: 2022-09-09
Article titleRecognition of Microbe- and Damage-Associated Molecular Patterns by Leucine-Rich Repeat Pattern Recognition Receptor Kinases Confers Salt Tolerance in Plants Image: Two of the study's 12 authors, corresponding author Yusuke Saijo and lead author Eliza Loo. When we think of plants, we usually don't think of the word "too stressed.
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Cancer Discovery A marker of chemotherapy resistance and prognosis for triple-negative breast cancer
Time of Update: 2022-09-09
Researchers at Baylor School of Medicine, the MIT Broad Institute, and Harvard University, as well as clinicians at Washington University in St. Louis, have identified biomarkers associated with chemotherapy resistance in triple-negative breast cancer (TNBC).
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How cells stay strong and flexible in the right place and at the right time
Time of Update: 2022-09-09
Then we consider: Maybe the capture bond could explain why living cells combine the elasticity of rubber with the strength of brick?"To test these ideas, the researchers measured the mechanical properties of the cytoskeletal network they reconstructed in the lab and worked with a biophysical team to pull a single bond.
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Can cancer cells turn back into normal cells?
Time of Update: 2022-09-09
A recent study explains how chemical modifications of messenger RNA, or so-called epigenetics, that alter the genetic material of a particular type of leukemia cell cause highly proliferating leukemia cells to transform into normal cells that can no longer reproduce .
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What makes the human brain unique?
Time of Update: 2022-09-09
Original title:Molecular and cellular evolution of the primate dorsolateral prefrontal cortex What makes the human brain different from all other animals, including our closest relatives?
Original title:Molecular and cellular evolution of the primate dorsolateral prefrontal cortex What makes the human brain different from all other animals, including our closest relatives?
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The research group of Kan Haidong and Cai Jing of our hospital has made progress in the field of environmental noise exposure assessment and research on environmental noise exposure and mental health of pregnant women
Time of Update: 2022-09-09
(Contributed by Xu Xueyi)Recently, the research group of Kan Haidong and Cai Jing from the School of Public Health of Fudan University and the research group of Associate Professor Xu Zhendong from the First Affiliated Maternal and Child Health Hospital of Tongji University have made progress in the research fields of environmental noise exposure assessment, environmental noise exposure and pregnant women's mental health .
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Researchers have discovered new ways to treat inflammatory bowel disease with lipid nanoparticles
Time of Update: 2022-09-09
Photo: Dr. Didier Merlin, a board professor at the Institute of Biomedical Research at Georgia State University and a senior research career scientist at ATR Inc Source: Georgia State UniversityAccording to a new study by researchers at Georgia State University's Institute of Biomedical Sciences, lipid nanoparticles targeted by the colon are a new therapeutic strategy for treating ulcerative colitis.
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Nature Sub-Journal: A Breakthrough in Cell Engineering! High-yielding CRISPR without viral vectors
Time of Update: 2022-09-09
"We demonstrated that we can design more than 1 billion cells in a single run, which is far more than the number of cells we need to treat a single patient," said first author Brian Shy. From double-stranded to single-stranded DNA CRISPR-Cas9, a system for editing genes within living cells, has been used as a basic research tool for the past decade.
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The structure of proteins is not static
Time of Update: 2022-09-09
"This is an interesting insight for us because it shows that in order to get more productive rubisco engineering results, we can't just look at the simplest answer, that regions of the enzyme actually interact with carbon dioxide," said lead author Albert Liu, a graduate student in Shih's lab.
