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Application of microglia AAV mutants in the development of a viral vector tool for efficient infection of microglia
Time of Update: 2022-09-14
1. AAV virus mutants that are highly effectively infected with microglia in vivo and at homeThe researchers screened the capsid proteins AAV-cMG.
WPP (~75%) capsid proteins (~75%) that achieved higher transfection microglia efficiency by randomly inserting amino acid sequences to cause mutations.
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Cell: Using AI to prepare for future coronavirus mutations
Time of Update: 2022-09-14
That's why the new approach takes a holistic approach: For each of these many potential viral variants, it predicts the ability to infect human cells, and whether it will be neutralized by antibodies produced by the immune system that are found in people who have been vaccinated and recovered.
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Classification of gliomas and key research targets of their molecular pathology
Time of Update: 2022-09-14
Molecular pathology of high-grade gliomas In the neuropathological diagnosis of gliomas, antibodies against proteins such as IDH (isocitric acid dehydrogenase), ATRX (alpha thalassemia/mental retardation syndrome X-linked), GFAP (glial fibrillary acidic protein), SYN (synaptophysin, EGFR (epidermal Growth factor receptor), p53 (tumor suppressor protein 53), and proliferation marker Ki-67 (MKI67) are the gold standard and are frequently used.
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Professor Seungjoon Oh's collaborative paper was published in the Journal of Empirical Finance
Time of Update: 2022-09-14
In view of this, the paper focuses on the Chinese region, starting from the state-owned city commercial banks, and conducts a study on how natural disasters affect post-disaster lending activities in affected areas and their economic consequences.
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Lepixin recruits scientific instrument product specialists and scientific instrument product assistants
Time of Update: 2022-09-14
net Founded in 2006 and headquartered in Karlsruhe, Germany, Labsun is a group of companies focusing on the development and production of high-end scientific instruments, market expansion, technical support and after-sales service.
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Effect of proper pipetting on 3D cell culture
Time of Update: 2022-09-14
Abstract 3D (3D) Cell Culture Download "Good Practices for Removing 3D Cell Culture Hydrogels"
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Weituo Qichuang successfully appeared in the 3rd China Robotics Academic Annual Conference
Time of Update: 2022-09-14
From August 3 to 5, the 3rd China Robotics Academic Annual Conference was successfully held in Harbin, and more than 1,000 experts and scholars from the field of robotics across the country attended
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For the first time, researchers have mapped spinning spiral waves in the human heart
Time of Update: 2022-09-14
Researchers at the Georgia Institute of Technology and clinicians at Emory University School of Medicine have a new understanding of these complex situations, and for the first time they have performed a high-resolution visualization of stable spiral waves in human ventricles.
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Hepatology Zhao Yang's research group achieves chemical induction of fibroblasts to become have:
Time of Update: 2022-09-14
32686 On July 26, 2022, Zhao Yang's research group at Peking University and the Joint Center for Life Sciences published a research result entitled Direct chemical induction of hepatocyte-like cells with capacity for liver repopulation in the international hepatology journal HEPATOLOGY 。 The study developed a system that uses a chemical small molecule method to step up endogenous transcription factors to induce fibroblasts to reprogram functional hepato parenchymal cells.
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ZEISS Microscopy Biopharmaceuticals Series Webinar: Special Topics in Tumor Immunity
Time of Update: 2022-09-14
Topic: Evaluation of tumor immune microenvironment Discovery of more biomarkers - Evaluation of TiME based on multicolor immunofluorescence (mIF) ※ mIF total solution ※ Application cases of mIF in innovative drug development ※ Establishment and validation of mIF methodology Scan the QR code to register A 35d neuronal organoid sample was taken by the ZEISS laser-chip layer scanning microscopy System Lightsheet 7 Cancer, from the very beginning of human birth, has accompanied human beings like shadows.
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Use 3D printing technology to "grow" edible steaks with cells
Time of Update: 2022-09-14
Figure 1: Overview of the bioprinting process Figure 2: Purification of primary bovine stem cells (bSCs) validation Figure 3: Characterization of primary bovine stem cell (bSCs) tissue manufactured with bioprinting Figure 4: Tendon gel bioprinting integrated with muscle, fat, and vascular tissue manufacturing Figure 5: Fibrous muscle, fat, and vascular tissue combined into an edible "steak" As a leader in 3D bioprinting and printing materials, CELLINK helps researchers create a healthy future.
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New imaging techniques have improved the diagnostic accuracy of most common skin cancers
Time of Update: 2022-09-14
According to a new study presented at the 31st Congress of the European Society of Dermatology and Venereal Diseases (EADV), a new imaging technique significantly improves the accuracy of the diagnosis of basal cell carcinoma (BCC), the most common skin cancer, compared to clinical and dermoscopy alone.
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Haier Biomedical Centrifuge Free Trial 3 Months Activity is in Full Swing!
Time of Update: 2022-09-14
Let the country's well-known universities, cutting-edge institutions, etcAll praised the approved Haier centrifugesDon't you want to experience it?Haier Biomedical Sends Benefits!Haier centrifuges are free to try for 3 months of activityThe heat is ongoingFirst come, first served!Event period: July 1 to September 30Participation form: Scan the following QR code to joinScan the code to register for a free trial
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Esco Scientific meets you at the 9th International Congress of Biopharmaceuticals in Hangzhou
Time of Update: 2022-09-14
The 9th International Biopharmaceutical Congress & Exhibition will be held on September 6-8, 2022 at the Hangzhou International Expo Center, and more than 250 exhibitors are expected to participate i
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Application of HPLC-MS/MS method in the detection of cyclophosphamide concentration in breast microdialysis fluid in rats
Time of Update: 2022-09-14
-END-For more information, please contact us for inquiries Phone : +86-0731-84428665 Contact: Manager Wu +86-180 7516 6076 Cyclophosphamide (Cyclophosphamide) is the most commonly used alkylating agent anti-tumor drug in clinical practice, which is widely used in the treatment of malignant lymphoma, breast cancer, ovarian cancer, cervical cancer, etc.
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Bertsie Lecture Hall: Chemiluminescent Inter-Aperture Interference Solutions
Time of Update: 2022-09-14
Hong Kong Beijing Shanghai Guangzhou Chengdu Jinan Welcome to pay attention to The official WeChat of Birch (WeChat public account: Bio-Gene)
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Birch Webinar: Latest Developments in Cutting-Edge Technology in High-Throughput Drug Development
Time of Update: 2022-09-14
cn Hong Kong Beijing Shanghai Guangzhou Chengdu Jinan BioAuxilium Enhanced Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Technology – THUNDER™ biomarker detection is designed to enable simple, fast, sensitive and reliable quantification of intracellular and intracellular supernatant biomarkers, ideal for cell signaling and cytokine analysis, with significant advantages over traditional ELISA: homogeneous, low sample size, one-step method, wider dynamic range, high throughput, stability and reproducibility.
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BioCon2022 9th Biopharmaceutical Conference & Exhibition opened in Hangzhou
Time of Update: 2022-09-14
Opening of the Conference Figure: Li Bei, founder of Shangtu Information Company, delivered a speech at the opening ceremony Photo: Mr. Li and six vips held the launching ceremony for the opening cer
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CD3/CD28 monoclonal coupling beads can continuously stimulate T cells and share many cases
Time of Update: 2022-09-14
According to relevant statistics, there are currently more than 180 dual antibodies in the clinical development stage and about 260 bispecific antibodies in the preclinical development stage, of which CD3 is the main target of dual antibody drug research [2]Second, T cell activation key "CD28" CD28 as a co-stimulating factor, with two most significant functions:(1) Auxiliary signal of T cell activation: Anti-CD28 can strengthen the proliferation and activation effects of PHA, ConA, anti-CD2McAb, anti-CD3McAb, etc.
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Rapeseed team reveals metabolite transporters BnaPPT1 and BnaBASS2 affecting canola grain oil...
Time of Update: 2022-09-14
BnaBASS2 overexpression significantly increased the expression level of multiple genes involved in lipid synthesis and oil formation, and promoted the accumulation of lipids in the grain.
BnaBASS2 overexpression significantly increased the expression level of multiple genes involved in lipid synthesis and oil formation, and promoted the accumulation of lipids in the grain.
