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A DNA swab solves the mystery of the origin of cancer
Time of Update: 2023-02-03
They developed a new software that accurately infers continental ancestry from tumor DNA and RNA.
They developed a new software that accurately infers continental ancestry from tumor DNA and RNA.
They developed a new software that accurately infers continental ancestry from tumor DNA and RNA.
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New software creates 3D nanostructures out of DNA to create miniature containers for delivering drugs
Time of Update: 2023-02-03
Science and Technology Daily Beijing, Dec. 27 (Reporter Zhang Mengran) According to the latest issue of Science Advances magazine, a new open-source software program developed by researchers at Duke
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Science Advances: Scientists discover the mechanism that plants use to control their mouths
Time of Update: 2023-02-03
The results were published in the journal Science Advances, "Stomatal CO2/bicarbonate sensor consists of two interacting protein kinases, Raf-like HT1 and non-kinase-activity activity requiring MPK12/MPK4。The researchers found that in a low-CO2 environment, a protein kinase called HT1 phosphorylates and activates the negative regulatory protein kinase CBC1 downstream, forcing guard cells on both sides of the stomata to swell and keep the stomata open for as long as possible to absorb carbon dioxide and meet the needs of photosynthesis.
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BBI: The team of Zhongda Hospital Affiliated to Southeast University discovered the reason why poor sleep hurts the brain!
Time of Update: 2023-02-03
Recently, Professor Ren Qingguo's team from the Department of Neurology, Zhongda Hospital Affiliated to Southeast University, published important research results online in the internationally renowned journal Brain, behavior, and immunity, they found that chronic SD can lead to intestinal dysbacteriosis, thereby activating the intestinal and brain NLRP3 inflammasomes, destroying the intestinal and blood-brain barriers, triggering the inflammatory response of the intestine and central nervous system (CNS), and then impairing cognitive function.
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Circulation: Cell reprogramming may reverse the body's heart fibrosis caused by a heart attack
Time of Update: 2023-02-03
Because adult cardiomyocytes have little ability to regenerate, resident cardiac fibroblasts synthesize extracellular mechanisms and form fibrosis after myocardial infarction (MI), leading to cardiac
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Cell Metabolism Thousands of unknown microproteins have been discovered in fat cells, one of which can increase appetite
Time of Update: 2023-02-03
Profiling Mouse Brown and White Adipocytes to Identify Metabolically Relevant Small ORFs and Functional Microproteins From left: Alan Saghatelian and Thomas MartinezObesity and metabolic diseases, such as diabetes, are very common in the United States.
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Cell: A self-positioning brain circuit was found in zebrafish
Time of Update: 2023-02-03
html In a new study, researchers from the Howard Hughes Medical Institute in the United States show that a multi-regional brain circuit allows juvenile zebrafish to track where they are, where they have been, and how they return to their original location after displacement.
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The inner ear cells are arranged in a checkerboard shape that allows us to hear sound
Time of Update: 2023-02-03
essentialsIn the Corti organ of the inner ear, there are two types of cells arranged in a checkerboard-like mosaic pattern; Hair cells are responsible for hearing and support cells.
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How old is your brain? Artificial intelligence accurately predicts human cognitive function and Alzheimer's disease
Time of Update: 2023-02-02
Now, a new artificial intelligence (AI) model, developed by USC researchers that analyzes magnetic resonance imaging (MRI) brain scans, can be used to accurately capture cognitive decline associated with neurodegenerative diseases such as Alzheimer's earlier than previous methods.
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Scenes reactivate novel mechanisms of addictive memory through inhibition-desuppression neural circuits
Time of Update: 2023-02-02
Recently, the research work of Professor Zheng Ping's research group of the Institute of Brain Sciences/State Key Laboratory of Medical Neurobiology of Fudan University has discovered a new mechanism by which scenes reactivate addictive memory through the inhibition-desuppression neural circuit.
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Reprogramming mature intestinal cells: The important role of collagen was discovered for the first time
Time of Update: 2023-02-02
essayCollagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation Image: Simplified epithelial plasticity shows how type I collagen initiates properties that alter the epitheliumSource: TMDU Center for Stem Cell and Regenerative MedicineResearchers at Tokyo Medical and Dental University (TMDU) have found that collagen deposition at the site of intestinal injury activates inflammation and regeneration signals in mouse and human cells Most cells have a fairly normal life: they are born, grow, age, and then die.
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A special study for rapid diagnosis of Covid-19-related inflammatory syndromes in children
Time of Update: 2023-02-02
The National Institutes of Health awarded eight research grants to improve new technologies for the early diagnosis of severe illness caused by SARS-CoV-2 infection in children. The new award follows
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Eur Heart J: The dietary supplement tridecylglycerol significantly resolves atherosclerosis
Time of Update: 2023-02-02
When we were young, our parents told us to eat vitamins so that we could grow big and strong. Now, in a new study, researchers from Osaka University in Japan have found that a dietary supplement can
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Chinese medical experts were the first to discover the mechanism and characteristics of single-cell metastasis in breast cancer
Time of Update: 2023-02-02
" Professor Shao Zhimin emphasized that clinical researchers urgently need to focus on this problem, find the metastasis mechanism and cell characteristics of breast cancer cells "running" to axillary lymph nodes and other organs, and then find drugs or therapeutic targets that can "block" this channel to further improve patient efficacy.
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Challenging established wisdom: The accumulation of Aβ in the brain is linked to Alzheimer's disease
Time of Update: 2023-02-02
"essayAmyloid futures in the expanding pathology of brain aging and dementia A new study from the USC Leonard Davis School of Gerontology challenges existing ideas that the accumulation of β amyloid (Aβ) in the brain is linked to Alzheimer's disease.
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ACS Nano: Development of nanoprobes for imaging and treatment of gliomas
Time of Update: 2023-02-02
Fig. 1 Structure and mechanism of co-assembled nanodiagnostic and therapeutic probes As a highly invasive and highly metastatic tumor, glioma is considered to be one of the most aggressive malignant brain tumors due to its challenges such as poor prognosis, high mortality and high recurrence rate.
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New Nature Cancer study identifies molecular differences between primary breast cancer and metastatic breast cancer
Time of Update: 2023-02-02
"essayMultiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis "This study involves a broad collaboration between many institutions to advance our understanding of breast cancer.
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The efficacy is better than that of Pfizer Paxlovid! The latest research data of Guangshengtang 3CL protease inhibitor was released
Time of Update: 2023-02-02
The results showed that Taizonidine (GST-HG171 tablets/ritonavir tablets) had superior anti-new coronavirus efficacy, and the nucleic acid conversion time of new crown patients was significantly better than that of the positive control Paxlovid and placebo control, and the safety and tolerability were good, which achieved the expected purpose of the trial and provided important supporting evidence for the later drug marketing.
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Scientists crack DNA's 'mechanical code'
Time of Update: 2023-02-02
An international team of researchers, led by Durham University in the United Kingdom, has revealed a previously unknown way in which nature encodes biological information in DNA sequences by deciphering the mechanical code of DNA.
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Cancer Sci: Scientists identify key molecular targets against pancreatic cancer in humans
Time of Update: 2023-02-02
Previous results have shown that cancer cells can express a high-level special enzyme encoded by the SETD1A gene, histone H3K4 methyltransferase, which can be added to the histone (necessary building blocks of chromatin) of specific targeted genes through methylation chemical groups, a process called methylation process, however, the molecular mechanism that induces overexpression of this enzyme and its effect on cancer cells.
