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Aging Cell: How interpersonal memories decay with age
Time of Update: 2022-09-21
Image credit: University of Maryland School of Medicine Figure: PDE11A memory enzyme (green) in the brains of young (left) and elderly (right) mice.
Image credit: University of Maryland School of MedicineFigure: PDE11A memory enzyme (green) in the brains of young (left) and elderly (right) mice.
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【Scientific research dynamics】Professor Xue Yu's team collaborated to propose a cross-omic core kinase inference algorithm
Time of Update: 2022-09-21
In this work, the researchers integrated phosphorylation group and transcriptome data to develop a cross-omics "central kinase inference" (CKI) algorithm.
In this work, the researchers integrated phosphorylation group and transcriptome data to develop a cross-omics "central kinase inference" (CKI) algorithm.
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UBA6 Crystal Structure Publication reveals which mutations in UBA6 selectively shut down ubiquitination and FAT10 function
Time of Update: 2022-09-21
A key to the study is to identify UBA6 mutations that can cause UBA6 selective FAT10 deficiency or ubiquitin deficiency.
A key to the study is to identify UBA6 mutations that can cause UBA6 selective FAT10 deficiency or ubiquitin deficiency.
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MIT conducted an in-depth study of duplicate protein sequences
Time of Update: 2022-09-21
They found that while LCRs will vary in different proteins and species, they often have a similar role — helping proteins join larger combinations, such as nucleoli, a type of organelle found in almost all human cells.
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How many drinks is too much?
Time of Update: 2022-09-21
When they analyzed the samples, the researchers found that a gene called hypoxia-inducing factor 3 α subunit( Hif3a for short) was associated with changes and behaviors in the brain after alcohol exposure, such as how long the rats stayed in the maze area closed (highly anxious) or open arms (low anxiety).
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South China Botanical Garden made progress in the resource and environmental impact assessment of the green ammonia remote coupling system
Time of Update: 2022-09-21
As a renewable energy medium suitable for long-distance trading, chloroamine has become a new hot spot in the energy transformation strategies of many countries and multinational companies. However,
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Save the Northern White Rhino! The 10th oocyte collection yields 5 new embryos
Time of Update: 2022-09-21
The biological rescue team collected 23 oocytes from Fatu, the younger of the two remaining female northern white rhinos.
The biological rescue team collected 23 oocytes from Fatu, the younger of the two remaining female northern white rhinos.
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Textbooks have been updated again, with different effects of elevated carbon dioxide concentrations on plant growth
Time of Update: 2022-09-21
"We found that the increase in phytic acid levels in plants needs to be tightly controlled in order for plants to grow in a high carbon dioxide environment.
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【Research Dynamics】Professor Guo Anyuan's team at the School of Life Sciences of Huazhong University of Science and Technology identified RNA features in a single extracellular vesicle for the first time
Time of Update: 2022-09-21
Figure 1 Article informationThis study proposes a high-throughput sequencing method for EVs based on the 10x Genomics platform, which explores the characteristics of the EVs transcriptome at the single EV level.
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Science: Are you anxious? This may be because of the effects of your gut microbiome
Time of Update: 2022-09-21
According to a prospective article recently published in the journal Science by a researcher at the University of Texas Southwest, there is now growing evidence that microbes in the human gut also affect a person's neurological and emotional health.
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Li Dan's research group and collaborators at Shanghai Jiaotong University explained the molecular mechanism of Hsp27 inhibiting pathological aggregation and toxicity of pTau in Alzheimer's disease
Time of Update: 2022-09-21
Alzheimer's disease (AD) as the most common neurodegenerative disease, the current global confirmed patients have exceeded 50 million, there is no specific drug, which seriously affects human life and
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iScience: A potential way to combat inherited neurological disorders
Time of Update: 2022-09-21
Image credit: Ioannou Laboratory, Department of Genetics and Genomic Sciences, Icahn School of Medicine, Mount SinaiScientists at the National Center for The Advancement of Translational Science (NCATS) at the Icahn School of Medicine in Mount Sinai, New York, and other researchers have reversed the effects of several life-threatening inherited neurodegenerative diseases— lysosomal storage disorders (LSDs) in patient cells and mice.
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A new tool to determine whether dilated cardiomyopathy has a genetic origin
Time of Update: 2022-09-21
Dr. García-Pavía and Dr. Luis EscobarScientists have developed a software application that can predict the possibility that dilated cardiomyopathy is caused by a genetic mutation.
Dr. García-Pavía and Dr. Luis EscobarScientists have developed a software application that can predict the possibility that dilated cardiomyopathy is caused by a genetic mutation.
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Molecular mechanism of DPY30 promoting methyltransferase activity of MLL complexes
Time of Update: 2022-09-21
TRS_Editor A{font-family:;font-size:12pt;} On August 17, the international academic journal iScience published the research results of The Chen Yong Research Group of the Center for Excellence in Molecular Cell Science (Institute of Biochemistry and Cell Biology) of the Chinese Academy of Sciences online: "DPY30 acts as an ASH2L-specific stabilizer to stimulate the enzyme activity of MLL family methyltransferases on.
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PNAS reveals the topological intersection center of the misfolded tetrahymbranenuclease
Time of Update: 2022-09-21
On September 6, 2022, Zhang Kaiming of the University of Science and Technology of China and professors Rhiju Das and Wah Chiu of Stanford University cooperated to publish important research results in the field of cryo-EM analysis of the three-dimensional structure of pure RNA online in the Proceedings of the American Academy of Sciences (PNAS) in a direct submission.
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PNAS mouse experiments have proven that exercise hormones can block the symptoms of Parkinson's disease
Time of Update: 2022-09-21
Researchers from the Johns Hopkins School of Medicine and the Dana Farber Cancer Institute in Boston have shown that during endurance or aerobic exercise, a hormone secreted in the blood lowers levels of proteins associated with Parkinson's disease and stops exercise problems in mice.
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A new target for the treatment of the most common lung cancer
Time of Update: 2022-09-21
essayAberrant TIMP-1 overexpression in tumor-associated fibroblasts drives tumor progression through CD63 in lung adenocarcinoma From left to right: Marselina Arshakyan, Elba Marín (front), Paula Duch, Cristina Teixidó, Noemí regart, Rafael Ikemori, Jordi Alcaraz, Marta Gabasa and Natalia Díaz.
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Why is pancreatic cancer so deadly? The latest research has uncovered new tools to improve pancreatic cancer treatment
Time of Update: 2022-09-21
Costa-Silva said: "Our study shows for the first time that by looking at the change in eVs in pancreatic cancer patients over time, we can know how well they respond to treatment.
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The team of Dong Ruijiao of Shanghai Jiaotong University and collaborators jointly developed a new strategy for the preparation of orderly porous nanofilms that can be used for accurate screening of drugs
Time of Update: 2022-09-21
This research has developed a new strategy to prepare ultra-thin films with a thickness of less than 10 nanometers in the orderly arrangement of macrocyclic molecules, which realizes the precise control of membrane pores and the accurate screening of drug molecules, and provides new ideas for expanding the application of porous membranes in drug separation.
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The key mechanism behind preventing the formation of obese brown adipose tissue
Time of Update: 2022-09-21
Researchers at the IRB barcelona, led by Dr. Antonio Zorzano, professor at the Faculty of Biology of the University of Barcelona (UB) and a member of CIBERDEM, describe a mechanism that regulates the correct formation of brown adipose tissue through autophagy, a natural cell renewal process.
