-
Liu Wenxian's research group published a paper at CMI to reveal that Myc inhibitors are found in the anti-tumor immune response.
Time of Update: 2022-10-01
The study takes the function of the proto-oncogene Myc in the anti-tumor immune response as the core of the study, and for the first time proves that the sensitivity of different T cell subsets to Myc inhibitors in the tumor microenvironment is determined by the expression of Myc protein, and the difference between Trg and CD8+ T for Myc inhibitor sensitivity in the tumor microenvironment is used to break the immune balance and enhance the anti-tumor immune response.
-
The Nature sub-journal RNA editing tool is a quick and easy tool for detecting COVID-19 and other diseases
Time of Update: 2022-10-01
Jie Yang, a postdoctoral researcher at Rice University, has led an effort to transform the Cas13 genome editing tool into a highly sensitive detector for detecting the presence of the SARS-CoV-2 virus that causes COVID-19.
-
Peng Yijie's research group of Guanghua School of Management published a paper proposing an efficient simulation optimization method to solve the problem of personalized decision-making in large-scale complex stochastic systems
Time of Update: 2022-10-01
Recently, an article by Peng Yijie's research group at Peking University's Guanghua School of Management titled "Efficient Learning for Clustering and OptimizingContext-Dependent Designs" was accepted by Operations Research 。 Operations Research has been recognized as the flagship journal in operations research and management science for publishing theoretical methods such as stochastic modeling, simulation, optimization and application in the fields of energy environment, financial engineering, operations management, and medical services.
-
New research from the Science subjournal calls into question old ideas about how hearing works
Time of Update: 2022-10-01
essayBest frequencies and temporal delays are similar across the low-frequency regions of the guinea pig cochlea Pictured: Anders Friedberg and Pierre Hakizmana measure the vibrations of the auditory organs.
-
New proteins were found to be associated with Alzheimer's disease risk
Time of Update: 2022-10-01
According to a new study from the University of Southern California, mutations in a newly discovered small protein are associated with a significant increase in the risk of developing Alzheimer's disease, expanding the known genetic targets of the disease and providing a new potential treatment pathway.
-
How did we first discover how our adaptive immunity evolved?
Time of Update: 2022-10-01
”A family of unusual immunoglobulin superfamily genes in an invertebrate histocompatibility complex When compatible colonies of longhorn hydra recognize each other as "themselves" by the Alr gene, they fuse together.
-
Science's surprising discovery in revising textbooks – chromosomes are actually "liquid"!
Time of Update: 2022-10-01
To draw these conclusions, published in the journal Science, scientists from CNRS, the Curie Institute, and the Sorbonne University, in collaboration with scientists at MIT, work in the laboratories of nuclear dynamics, physical chemistry, cell biology, and cancer, attaching magnetic nanoparticles to a small fraction of the chromosomes of living cells.
-
PNAS: Aging, Intergenerational Change, and Urban Energy Consumption in China
Time of Update: 2022-10-01
Figure 1 Mechanism of the impact of population transition on energy consumption Figure 2 Prediction result. (A) changes in residents' energy consumption caused by population; (B) population, househol
-
The Institute of Aquatic Sciences reveals how the East Asian monsoon climate has created a rich diversity of freshwater fish species in China
Time of Update: 2022-10-01
These work have enhanced understanding of the evolutionary patterns of freshwater fish in East Asia and provided a model for understanding the impact of major historical events on biota evolution 。 The work was published online in SCIENCE CHINA Life Sciences under the title "Monsoon boosted radiation of the endemic East Asian carps" (Article Link: http://engine.
-
Nature sub-issue: Just turn off this backup gene and the cancer will be alleviated
Time of Update: 2022-10-01
Metabolic collateral lethal target identification reveals MTHFD2 paralog dependency in ovarian cancer Researchers at the University of Michigan and Indiana University have shown that the way tumor cells grow uncontrollably is also a weakness that can be harnessed to treat cancer.
-
Why do people have a fever? See how Academician Zhuang Xiaowei uses MERFISH to answer this question
Time of Update: 2022-10-01
MERFISH technology detects gene expression by means of super-resolution fluorescence in situ imaging with single-molecule detection sensitivity, defines different cell types, retains spatial location information, and more intuitively displays that the distribution of VMPO LPS neuronal cells in the tissue with the ependymal membrane and the cells that make up the blood-brain barrier has spatial proximity, as a strong evidence to find that VMPOLPS neuronal cells are activated by paracrine cells.
-
"Mining plant ITS sequences from second-generation sequencing data and using them to identify variety lines" was authorized by the national invention patent
Time of Update: 2022-10-01
. TRS_Editor P{margin-top:0px;margin-bottom:12px;line-height:1. 8;font-family:;font-size:12pt;}. TRS_Editor DIV{margin-top:0px;margin-bottom:12px;line-height:1. 8;font-family:;font-size:12pt;}. TRS_E
-
The Chengdu Institute of Biology has revealed the body color polymorphisms and information transmission functions of the rare and endangered species crocodile lizard
Time of Update: 2022-10-01
. TRS_Editor P{margin-top:0px;margin-bottom:12px;line-height:1. 8;font-family:;font-size:12pt;}. TRS_Editor DIV{margin-top:0px;margin-bottom:12px;line-height:1. 8;font-family:;font-size:12pt;}. TRS_E
-
The results of the affiliated Ruijin Hospital and Renji Hospital teams were published in the journals The Lancet and Nature, and the first clinical study for Chinese was published
Time of Update: 2022-10-01
Explain the importance of protecting the elderly population during the COVID-19 pandemicThe Lancet published the blockbuster results of the affiliated Ruijin HospitalRecently, Professor Wang Weiqing, Department of Endocrinology and Metabolism, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, and National Clinical Research Center for Metabolic Diseases led a team to publish a corresponding article in The Lancet: "Protecting older people: a high priority during the COVID-19 pandemic".
-
The Xi's Qiaoran research group in the School of Life Sciences revealed that lncRNA-Smad7 regulates mouse embryos by mediating TGF-β and BMP signaling pathways...
Time of Update: 2022-10-01
Figure: The Nodal signaling pathway transcription activates the expression of long-chain non-coding RNA lncRNA-Smad7, which binds to the promoter region of Bmp2, inhibits the transcriptional expression of Bmp2, and then regulates the differentiation process of mouse embryonic stem cells to cardiomyocytes.
-
NAR: PhaSepDB, a new phase protein separation database
Time of Update: 2022-10-01
Recently, Li Tingting's research group in the Department of Medical Bioinformatics of Peking University School of Basic Medicine published an article online in the journal Nucleic Acids Research "PhaSepDB in 2022: annotating phase separation-related proteins with droplet states, co-phase separation partners, and other.
-
Cultivating Developing Neurons: How Major Immune Cells Promote Brain Development Through Interactions with Newborn Neurons
Time of Update: 2022-10-01
essayMicroglial control of neuronal development via somatic purinergic junctions Photo: Microglia (green) contact mouse hippocampal neoneurons (red) The Neuroimmunology Laboratory of the Institute of Experimental Medicine (IEM) in Budapest, Hungary, led by ádám Dénes, described the presence of sites of direct interaction between microglia and developing neuronal cell bodies and revealed their role in brain development.
-
Embryonic macrophages: monitoring hematopoietic stem cell quality determines hematopoietic clonality
Time of Update: 2022-10-01
The authors studied the blood development of zebrafish embryos and found that hematopoietic stem cells and progenitor cells (HSPCs) emerge from the abdominal wall of the dorsal aorta (VDA), enter the circulatory system, and stay in the embryonic niche, a vascular plexus called caudal hematopoietic tissue (CHT).
-
Ultra-sensitive immunological detection technology is applied to the response of new crown antibodies
Time of Update: 2022-10-01
The research team proposed a bold hypothesis: after infection or vaccination, the emergence of SARS-CoV-2-specific antibodies is a continuous process, so using a method with higher sensitivity than ELISA, it is possible to shorten the serum transition time of IgG and IgM, that is, it is expected to detect the new crown virus infection with immunoassay at an earlier point in time.
-
Fight against "sedentary" has been saved! "Special" muscle can promote glucose and fat burning
Time of Update: 2022-10-01
Marc Hamilton, a professor of health and human behavior at the University of Houston, has discovered one of the best activation methods — he pioneered the "Flounder Muscle Push-ups" (SPU), which can effectively boost muscle metabolism for hours, even while sitting.
