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Human cocaine and heroin addiction is associated with damage to specific brain circuits in animals
Time of Update: 2022-10-12
The results highlight the potential specificity of the apparent prefrontal cortex connection to the neuropathology of drug addiction Source: Mount Sinai Health SystemA study conducted by researchers at the Icahn School of Medicine at Mount Sinai and Baylor College of Medicine showed that the brain's white matter, previously involved in animal studies, is now thought to be particularly impaired in the brains of cocaine or heroin addicts.
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Nature Immunology Li Huabing research group and cooperation team reported that tRNA-m1A modification is CD4+T fine...
Time of Update: 2022-10-12
Wilson Distinguished Service Professor, Department of Chemistry,University of Chicago Investigator, Howard Hughes Medical Institute Li Huabing's team has been focusing on the study of the impact of RNA modification on immune cell development and function, especially on the exploration of the epigenetic regulation of T cell RNA, and published a series of high-level research results, which has formed a certain academic influence.
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Cell's first result: no harm to beneficial intestinal bacteria, precise inhibition of pathogenic microorganisms
Time of Update: 2022-10-04
Original title:Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation The myriad of microbes in our gut are collectively known as the microbiome, and they are considered important to our health, but they can also breed bacteria that cause inflammatory bowel disease or other diseases.
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For the first time, Guo Song's team from the School of the Environment quantified the full volatile components of catering sources, revealing the effects of cooking methods and edible oil types on cooking emissions
Time of Update: 2022-10-03
2c00207 On August 2, 2022, the Journal of Atmospheric Chemistry and Physics published the latest research results of researcher Guo Song's research group in the School of Environmental Science and Engineering of Peking University 。 The article is titled "Impact of cooking style and oil on semi-volatile and intermediate volatility organic compound emissions from Chinese domestic cooking", Song Kai, a 2019 doctoral student in the research group, is the first author of this paper.
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One of the three major challenges of the Great Breakthrough Human Proteome Project - protein identification of shear variants
Time of Update: 2022-10-03
Professor Zhang Gong of Jinan University developed the three-generation full-length translation group sequencing technology, broke through the protein product identification of shear variants of one of the three major problems of the human proteome project, found that there are thousands of mRNA shearing variants in human cells that have never been included in the database can be translated into proteins, and identified the characteristic peptides of some of the new shear variants at the protein level by mass spectrometry.
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PNAS overturns the long-held assumption that the true origin of South American canids is
Time of Update: 2022-10-03
Over the past few thousand years, a number of key genetic mutations have led to rapid extreme changes in height, body size and diet in South American canines, and these genetic mutations were introduced through artificial selection breeding, resulting in a more common canine – the domestic dog – of alarming diversity.
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Science Immunology: When alveolar macrophages do not work properly
Time of Update: 2022-10-03
(2022): “C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages,” Science Immunology, DOI: 10.
(2022): “C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages,” Science Immunology, DOI: 10.
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Nanjing Medical University Cancer Cell published a paper: A new genetic mechanism of lung cancer pathogenic variants
Time of Update: 2022-10-03
On September 15, 2022, Shen Hongbing and Hu Zhibin's research group at the School of Public Health of Nanjing Medical University published a report entitled "Analyses of rare predisposing variants of
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Exercise may be key to developing treatments for rare movement disorders
Time of Update: 2022-10-03
"Activation of TrkB - Akt signaling rescues deficits in a mouse model of SCA6 Spinal cerebellar ataxia (SCA6) is an inherited neurological disorder that has a debilitating effect on motor coordination.
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Huazhong University of Science and Technology: Using microbiome big data to help predict the three-dimensional structure of proteins
Time of Update: 2022-10-03
At present, the interrelationship between the environment and human health is receiving more and more attention, especially in today's society where the new crown pneumonia is ravaging the world, and
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A study of the variation of two large bees spanning 21,000 years
Time of Update: 2022-10-03
, of the Coevolution Research Group of Banna Botanical Garden, discussed the potential distribution areas and possible coexistence areas of the two large bees under the background of global climate change, as well as the key factors affecting the distribution of the two large bees, thus providing a scientific basis for the protection of these two important pollinators.
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Cell's new research reveals the molecular origins of the genetic disease cystine disease
Time of Update: 2022-10-03
Structural and biophysical studies of human cystine have revealed the molecular mechanisms and conformational kinetics of proton-coupled lysosomal amino acid transport.
Structural and biophysical studies of human cystine have revealed the molecular mechanisms and conformational kinetics of proton-coupled lysosomal amino acid transport.
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Causes of brain dysfunction in patients with Huntington's disease
Time of Update: 2022-10-03
It is reported that the research team of the Institute of Brain Science of the Korea Academy of Science and Technology (KIST, President Yoon Seok-jin) found that the activity of the focus adhesion kinase (FAK) protein, which plays an important role in the movement of nerve processes and normal synaptic formation in the brain tissue of HD patients, was significantly reduced.
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Cell Systems: The universal rules that shape cellular power stations
Time of Update: 2022-10-03
essayEvolutionary inference across eukaryotes identifies universal features shaping organelle gene retention Mitochondria are compartments within cells, the so-called "organelles," that provide chemical energy for our activities, thoughts, and lives.
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Science Your family has a long history and unique gut "army"
Time of Update: 2022-10-03
Scientists at the Tübingen Institute for Biological Research have now found that gut microbes have a parallel evolutionary history with their human hosts: these microbes co-evolved in the human gut environment for hundreds of thousands of years.
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The research results of Wang Ruzhu's team at Shanghai Jiaotong University have achieved large-scale water production in semi-arid areas
Time of Update: 2022-10-03
Recently, the ITEWA team led by Professor Wang Ruzhu of Shanghai Jiaotong University published a paper in Nature Communications entitled Exceptional water production yield enabled by batch-processed portable water harvester in semi-arid climate.
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Dirty kitchen windows can be a refuge for toxic pollutants
Time of Update: 2022-10-03
The evolution of surface structure during simulated atmospheric ageing of nano-scale coatings of an organic surfactant aerosol proxy Under the fatty acid protective film of cooking emissions, dirty windows can hide potentially harmful pollutants — pollutants that can stay on windows for long periods of time.
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Mitochondrial RNA modifications may promote aggressive spread of cancer
Time of Update: 2022-10-03
When researchers block the function of enzymes responsible for RNA modification in cancer cells, the number of metastatic cancer cells decreases, and in a laboratory setting, specific antibiotics that inhibit protein synthesis in mitochondria may also inhibit the aggressive spread of cancer cells.
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Explore how living cells regulate the growth of organelles
Time of Update: 2022-10-03
She plans to use mathematical modeling and simulation to quantitatively analyze the mechanisms used by cells to maintain competing structures in shared pools.
She plans to use mathematical modeling and simulation to quantitatively analyze the mechanisms used by cells to maintain competing structures in shared pools.
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T cells destroy cancer cells with force
Time of Update: 2022-10-03
Source: James Cremasco, Daryan Kempe and Maté Biro T cells (blue) snuggle up on targeted cancer cells (orange) and produce forces to promote the killing of pore-forming proteins (yellow).
