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WHO I. Meningoma liver metastasis
Time of Update: 2020-11-08
MRI imaging showed that the right-hand top pillow leaf tumor, the size of 6×3×3.5 cm, uneven reinforcement, visible intracranial hemorrhage; hemorrhage under the epidural and in the top leaf trench of the right hemisphere of the brain (Figure 1).
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Advanced kidney cancer "immune and targeted" first-line treatment! The Opdivo-Cabometyx combination is on the market in Japan, beating Sutt!
Time of Update: 2020-11-08
October 31, 2020 // -- Exelixis corporation recently announced that its clinical development and commercialization partners takeda and Ono Pharma, which are responsible for the clinical development and commercialization of the cancer drug Cabozantinix in Japan, have The Ministry of Health, Labour and Labour (MHLW) submitted a supplementary application seeking approval for Cabomyx's joint anti-PD-1 therapy Opdivo (Odivo, common name: nivolumab, Navulyu monoanti) for the treatment of non-excisive, advanced or metastatic renal cell carcinoma (RCC) patients.
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Rhythmic regulatory molecule BLOCK alters the micro-environment of gliomas by immunosuppressing small glial cells
Time of Update: 2020-11-07
Peiwen Chen of the MD Anderson Cancer Center at the University of Texas, USA, et al., found that the complex of circadian rhythm-regulating molecules BLOCK and BMAL1 promotes the dry maintenance of GBM stem cells and activates downstream OLFML3 to promote immunosuppressive small glial cells that alter tumor microencepts, the results of which were published in the March 2020 issue of Cancer Discovery.
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GUT: Effects of postoperative colonoscopy review intervals on the risk of advanced lesions in patients with colonosis
Time of Update: 2020-11-06
end point of this study is an AN event, defined as ≥10 mm low-level heterogeneity, high-level heterogeneity or immersive tumor lesions.
3,926 patients, with an average age of 57.3 years, 2,440 men (62%) and 2,166 completed follow-up visits, including 1,087 in 2 review groups and 1,079 in 1 review group.
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GUT: Risk of primary tumors in the subsequent digestive system of childhood tumor survivors
Time of Update: 2020-11-06
PanCareSurFup queue, which includes a total of 69,460 child tumor survivors in 12 European countries, looked at the standardized incidence of primary tumors in the follow-up digestive system (SIRS), absolute additional risk, and cumulative incidence of the population.
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J Clin Oncol: Breast cancer patients with PALB2 embryo mutations can also benefit from PARPi treatment
Time of Update: 2020-11-06
recruit MVC patients who carry HR-related gene germ line mutations (queue 1) other than BRCA1/2, or THOSE-related gene (including BRCA1/2) system mutations (queue 2).
PARP inhibition can effectively treat MPC patients with gPALB2 or SBRCA/2 mutations, greatly expanding the population of breast cancer patients who may benefit from PARPi therapy.
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The results of 20 years of large-scale registration showed that diabetes was not associated with a risk of rupture of abdominal aortic aneurysms
Time of Update: 2020-11-06
patients with ruptured abdominal aortic aneurysms were paired 1:1 with patients undergoing selected surgery, depending on the patient's gender, age and year of diagnosis.
patients with total abdominal aortic aneurysms, no diabetes was found to have a protective effect on abdominal aortic aneurysm rupture.
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Lancet oncol: Biomarkers guide the effectiveness of treatment for non-small cell lung cancer
Time of Update: 2020-11-06
Lung Cancer Master Program (Lung-MAP; S1400) is a complete biomarker-driven master program designed to address the unsolved need for better treatment of squamous non-small cell lung cancer.
Lung-MAP (S1400) has achieved its goal of rapidly addressing biomarker-driven treatment for squamous non-small cell lung cancer.
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Early diagnosis and treatment of stomach cancer still needs to be strengthened, and the dawn of immunotherapy has been dawned
Time of Update: 2020-11-06
In autumn and October, as the weather cools down, the appetite naturally warms up. pay attention to the "people to eat for the day" Chinese in autumn has a "paste autumn" custom. old saying that aut
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J Clin Oncol: According to the UGT1A1 genotype quantification of Iliticon can significantly improve the prognostic prognostics of patients with advanced rectal cancer
Time of Update: 2020-11-06
4 and 6 patients in the control group and the experimental group received complete clinical remission, respectively.
3/4 toxicity in 11 (6%) and 68 (38%) patients in the control group and the experimental group, respectively.
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Systematic review and meta-analysis of long-term interventional therapy after in-cavity aneurysm repair
Time of Update: 2020-11-06
, the researchers conducted a systematic review and meta-analysis of the available literature to determine the long-term degree of freedom and re-intervention rates of EVAR intervention over time.
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The 8th National Conference on Blood Tumors, the latest treatment strategy for multiple myeloma in China, see Professor Qiu You give you a clear article
Time of Update: 2020-11-05
patient prognosis differences are large in china, large triple-A hospitals have blood disease diagnosis and treatment centers, generally distributed in developed cities, these centers MM patients' survival time has been significantly improved.
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Cancer cell: Scientists have developed an artificial intelligence system that allows AI to match the best combination of drugs for cancer patients
Time of Update: 2020-11-05
DrugCell combines the internal workings of the model with the hierarchy of human cell biology to predict the response of any drug in any cancer and to design effective combination therapies.
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NEJM: A study of the efficacy of oxytosinib as an auxiliary treatment after surgery for non-small cell lung cancer
Time of Update: 2020-11-05
At 24 months, 90 percent of patients in the Ositeni group had stage II to IIIA, and 44 percent of patients in the placebo group in stage II to IIIA achieved disease-free survival (the total risk ratio of recurrence or death was 0.17).
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Nature: In addition to anti-PD-1, immunosuppressors can also be suppressed by phosphatase collection
Time of Update: 2020-11-05
mouse models of small cell lung cancer and colon cancer, MICER-PD1 reduced tumor progression in general, and the study proposed an alternative method of weakening cell surface sensor signals, called inhibition of the subject through phosphatase collection (RIPR).
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Cell Death Dis: RASSF1A inhibits the deterioration of nasopharyngeal cancer through YAP1 dependence
Time of Update: 2020-11-05
the level of expression of RASSF1A was associated with self-renewal and tumor-ogenogenization of nasopharyngeal cancer cells in the study, the researchers found that the expression of RASSF1A inhibited the malignancy of NPC cells.
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From the past: Professor Li Ning talks about rare tumors
Time of Update: 2020-11-05
In September 2020, the Official Public Number of the Drug Clinical Trial Research Center (GCP) of the Oncology Hospital of the Chinese Academy of Medical Sciences opened a special "Rare Tumors, Where are the Drugs" column, which aims to raise the industry's attention to rare tumors, and to study doctors and pharmacists to share information, treatment status and (potential) therapeutic drugs on several rare tumors.
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Selenium is an essential element to improve resistance and prevent cancer! Eat more of these foods without fear of selenium deficiency
Time of Update: 2020-11-05
lack of selenium, you will be more likely than others to get 5 diseases in the professional field, selenium is well-known, both "heart protection God" praise, also known as the "king of cancer." , can antioxidant, delay aging, can improve immunity, can effectively protect the brain ...
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Cancer Discov: Do cancer cells want to metaste from lymphatics? Scientist: I'm sorry, it's not the way
Time of Update: 2020-11-05
To solve this problem and explore ways to limit lymphatic metastasis, scientists at the University of Heidelberg and the German Cancer Research Center modeled the lymphatic system in mouse tumors and found that antibodies targeting lymphatic endodertic cell signaling molecules can cause lymphatic tube death in tumors and inhibit metastasis, thereby prolonging the survival of mice.
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NEJM: 2 years in advance! Wu Yilong, in a team of 284 centers around the world and in China, found that surgery and precision-targeted treatment reduced the risk of recurrence after early and mid-stage lung cancer
Time of Update: 2020-11-05
In summary, the study found that in NSCLC patients who were positive for EGFR mutations in periods IB through IIIA, patients who received oxytinib had significantly longer disease-free lifetimes than those who received placebo (for patients with early-to-mid-stage lung cancer from IB to IIIA and with gene mutations, their risk of tumor recurrence decreased by 83 percentage points after pre-surgical removal with the aid of third-generation targeted drugs).
