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The first TIL cell therapy submits a rolling marketing application
Time of Update: 2022-09-06
On August 25, 2022, Iovance Biotherapeutics announced the initiation of a rolling marketing application for the TIL therapy lifileucel for the treatment of advanced melanoma that has progressed after PD-1/PD-L1 therapy.
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CT Diagnosis of Common Rib Tumors and Tumor-like Lesions
Time of Update: 2022-09-06
CT manifestations: multiple lesions are the main features of metastatic tumors; most of them are combined with thoracic spine metastasis, and the lesions are mainly osteolytic destruction, and there are also ivory-like osteogenic metastases .
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Nature Cancer: Cancer immunotherapy may impair fertility
Time of Update: 2022-09-06
The study shows that commonly used cancer immunotherapy drugs, such as immune checkpoint inhibitors, cause permanent damage to the ovaries and the follicles they store in mice, reduce the number and quality of eggs, interfere with ovulation, and disrupt reproductive cycles .
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Clinical significance of triple examination for liver cancer screening
Time of Update: 2022-09-06
In order to better assist the clinical diagnosis and differential diagnosis of malignant liver lesions, as well as the early warning and the evaluation of the prognosis of liver cancer, the laboratory can carry out the triple test for liver cancer screening (abnormal prothrombin, alpha-fetoprotein heterogenous body and ratio)Reference range:Clinical significance:(1) Screening and early diagnosis of liver cancerSerum DCP levels were mildly elevated in patients with liver diseases other than HCC, but significantly elevated in HCC patients .
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Nature: Scientists discover key protein that inhibits pancreatic cancer metastasis
Time of Update: 2022-09-06
Paper link:#additional-information Pancreatic ductal adenocarcinoma (PDAC) is an insidious onset and a malignancy with a poor prognosis, with a five-year survival rate of less than 7%, and is characterized by prominent genomic aberrations and increased glycolytic phenotypes .
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JAMA sub-issue: 270,000 people were followed up for 12 years: exercise can reduce cardiovascular and cancer risks!
Time of Update: 2022-09-06
Although there is strong evidence that physical activity has a beneficial role in longevity, there is little insight into how engaging in the same amount of different leisure-time activity types (such as running and cycling) is associated with mortality risk, and whether some activities compare to others There are greater benefits that are poorly understood .
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J Clin Oncol: Sacituzumab govitecan in endocrine-resistant HR+/HER2– advanced breast cancer
Time of Update: 2022-09-06
The prognosis of patients with hormone receptor-positive (HR+) human epidermal growth factor receptor 2-negative (HER2-) endocrine-resistant metastatic breast cancer treated with sequential single-agent chemotherapy is poor .
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Liver cancer comes, urine prophet?
Time of Update: 2022-09-06
In the early stage of cancer, there will be no obvious pain, and some liver cells can work normally, because the body will not experience abnormal symptoms immediately .
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The Lancet: Update on the world's largest real-life prospective study!
Time of Update: 2022-09-06
KBP-2020 is similar to two previous KBP studies to compare and capture trends in lung cancer patient and tumor characteristics over the past 20 years .
KBP-2020 is similar to two previous KBP studies to compare and capture trends in lung cancer patient and tumor characteristics over the past 20 years .
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Can Universal CAR-T Cross Brain Tumor "No Man's Land" DJS
Time of Update: 2022-09-06
Click on the image for the DJSeedin agendaWritten by Cheng LongIn the field of cell therapy, universal CAR-T (UCAR-T) has shown broader therapeutic prospects, but the allogeneic rejection limits the application of UCAR-T in the field of tumors, especially solid tumors .
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Eur Urol Focus: Local tumor destruction versus partial nephrectomy for cancer-specific mortality in T1a renal cell carcinoma
Time of Update: 2022-09-06
In a large-scale analysis of cancer-specific mortality (CSM) in patients with T1a renal cell carcinoma (RCC), there are very few large-scale analyses of local tumor destruction (LTD) relative to partial nephrectomy (PN) .
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European Radiology: Pathology-Grade Analysis of MYCN Amplification in Neuroblastoma Using Apparent Diffusion Coefficient (ADC) Histogram Analysis!
Time of Update: 2022-09-06
Recently, a study published in the journal European Radiology evaluated the role of whole-tumor apparent diffusion coefficient (ADC) histogram analysis in identifying MYCN amplification status in neuroblastoma for a noninvasive, accurate, and comprehensive preoperative assessment of neuroblastoma.
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JAMA Netw Open: After 6 years of tracking more than 40,000 IVF cases, we came to this conclusion...
Time of Update: 2022-09-06
However, children born to parents with fertility problems or undergoing infertility treatment have been found to be at increased risk of epigenetic alterations and adverse perinatal outcomes that may be associated with childhood cancer .
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Implementation guidelines for multidisciplinary team diagnosis and treatment of stage IV primary lung cancer in China
Time of Update: 2022-09-06
Excerpt Although patients with stage IV primary lung cancer have a variety of treatment options, due to the complexity of the disease and the heterogeneity of the disease, the problems that arise in
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5 lifestyle habits that can effectively prevent stomach cancer
Time of Update: 2022-09-06
China is a country with a high incidence of gastric cancer, and the patients with gastric cancer were mostly middle-aged and elderly people .
China is a country with a high incidence of gastric cancer, and the patients with gastric cancer were mostly middle-aged and elderly people .
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Cancer Cell: BioNTech new paper - tumor neoantigen vaccine + chemotherapy + PD-1, a three-pronged approach to treat lung cancer
Time of Update: 2022-09-06
The study reports a phase 1b clinical trial combining the individualized neoantigen cancer vaccine NEO-PV-01 with chemotherapy and the anti-PD-1 drug pembrolizumab in metastatic non-squamous non-small cell lung cancer.
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MRI can detect early liver cancer, primary liver cancer has high incidence in my country
Time of Update: 2022-09-06
CT can detect early-stage liver cancer with a diameter of about 1 cm, and the main coincidence rate for clinical diagnosis and examination of liver cancer is as high as 90%; while MRI can greatly improve the incidence of liver cancer when using a new type of hepatocyte-specific contrast agent, Pumex.
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Fundamental Research: He Jing's team reviewed the research progress of neuroblastoma liquid biopsy
Time of Update: 2022-09-06
Recently, He Jing's research group from the Surgery Laboratory of Pediatric Research Institute of Guangzhou Women's and Children's Medical Center published a research paper entitled: Advances in liqui
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【CLEAR one case per day】A case of hemophilic femoral pseudotumor and pathological fracture
Time of Update: 2022-09-06
Post-traumatic X-ray films showed the fracture of the cortical bone defect in the middle of the femur, the broken ends were displaced and overlapped, the localized soft tissue mass-like density was enlarged compared with the previous one, and the edge was clear .
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15 types of tumors that occur on the ribs, have you seen them all?
Time of Update: 2022-09-06
Lesions that occur in the ribs are mainly characterized by slightly swollen bone destruction, with clear borders and sclerotic edges, and flocculent cartilage tissue or punctate and patchy calcifications can be seen inside the lesions, which are consistent with the imaging manifestations of general chondromas .
