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The exploration process of mucosal melanoma: combination therapy ignites the hope of survival, and looks forward to more Chinese wisdom
Time of Update: 2022-10-13
A study at ESMO Annual Meeting 2022 evaluated the efficacy of adjuvant PD-1 inhibitor therapy in patients with resected stage III/IV atrial or mucosal melanoma[3].
A study at ESMO Annual Meeting 2022 evaluated the efficacy of adjuvant PD-1 inhibitor therapy in patients with resected stage III/IV atrial or mucosal melanoma[3].
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BMJ: Eat less ultra-processed foods, especially men! Data from more than 200,000 people show that men's intake of large amounts of ultra-processed foods is associated with a 72% increased risk of distal coloral cancer
Time of Update: 2022-10-13
Association of ultra-processed food consumption with colorectal cancer risk among men and women: results from three prospective US cohort studies BMJ 2022; 378 :e068921 doi:10.
Association of ultra-processed food consumption with colorectal cancer risk among men and women: results from three prospective US cohort studies BMJ 2022; 378 :e068921 doi:10.
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Express treatment of prostate cancer, Pfizer PARP inhibitor combination therapy reached the main clinical endpoint of Phase 3
Time of Update: 2022-10-13
▎Editor of WuXi AppTec content teamPfizer today announced that its combination therapy of PARP inhibitor Talzenna (talazoparib) and Xtandi (enzalutamide) has achieved positive results in the TALAPRO-2
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Optic tube top abrasion during saddle nodule meningioma
Time of Update: 2022-10-13
At the cranial inlet port of the optic neural tube, the optic nerve is covered by a sickle ligament extending from the anterior bed process to the saddle nodule (Figure 1), and the length of the covered nerve varies from 1 mm to 1 cm.
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The WU-KONG6 study was honored in the 2022 ESMO ESMO Sulvotinib Strength, Attacking the EGFR 20 Exon Insertion Mutation
Time of Update: 2022-10-13
In addition to this year's ESMO conference, suvotinib has previously reported 2-3 in the internationally renowned journal "Cancer Discovery" with a high impact factor and other influential international conferences (such as ASCO, WCLC), and the report of this ESMO conference once again confirms the broad application prospects of suvoltinib in the future, suggesting that it is expected to change the treatment pattern of EGFR 20 exon insertion mutation.
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2022CSH Prof. Dehui Zou: Application Status of CAR-T Cell Therapy
Time of Update: 2022-10-13
Could you please briefly talk about the current application of CAR-T cell therapy in hematological malignancies worldwide?Professor Zou DehuiIn the past ten years, cell therapy drugs represented by CAR-T have developed rapidly, and commercial CAR-T products have been listed at home and abroad.
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How much alcohol do you drink per day to increase your risk of cancer? JAMA sub-journal gives the answer!
Time of Update: 2022-10-13
A 2020 study published in the British Journal of Cancer analyzed the adjusted risk-adjusted ratio (HR) of cancer associated with total alcohol intake (drink/week) by ≥ Australian participants aged 226162 45 years (2006-2009) [4].
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The future of biased IL-2 is uncertain, and Nektar seeks to merge
Time of Update: 2022-10-13
com/rising-from-the-il-2-ashes-and-drastic-reorg-nektar-in-merger-talks-with-puretech/After failing three consecutive IL-2 clinical trials, Nektar began seeking concorposion.
com/rising-from-the-il-2-ashes-and-drastic-reorg-nektar-in-merger-talks-with-puretech/After failing three consecutive IL-2 clinical trials, Nektar began seeking concorposion.
com/rising-from-the-il-2-ashes-and-drastic-reorg-nektar-in-merger-talks-with-puretech/References:https://endpts.
com/rising-from-the-il-2-ashes-and-drastic-reorg-nektar-in-merger-talks-with-puretech/
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Can the new model be useful in reducing overtreatment of prostate cancer?
Time of Update: 2022-10-13
Through a series of studies and data, the organization has developed a "MUSIC diagnosis and treatment model" suitable for active monitoring of prostate cancer patients, and proposed guidelines such as imaging standards.
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Professor Changlin Zhao: Why is a colonoscopy preferred for fine screening for coloral cancer? How can I improve the detection rate and early diagnosis accuracy of colorectal tumors on colonoscopy?
Time of Update: 2022-10-13
Author:Zhao ChanglinThis article is authorized by the author to publish Memai, please do not reprint without authorization. Expert profileProfessor Zhao ChanglinNational Grade III Professor Ph. D. in
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JEM: Fu Yangxin/Peng Hua collaborated to develop a new generation of tumor-specific anti-PD-1-IL-15 immunotherapy drugs
Time of Update: 2022-10-13
The "pro-cytokine" prodrug strategy previously proposed by Peng Hua's research group of the Institute of Biophysics of the Chinese Academy of Sciences can effectively reduce toxicity (Cell Res, 2021).
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The second-line treatment of liver cancer has added "fierce general"! The successful approval of the indication for remoxizumab has brought more hope to patients in China
Time of Update: 2022-10-13
The results showed that the study reached the main positive endpoint of OS, and the survival benefit of patients with advanced liver cancer with advanced liver cancer with remoxizumab single-agent second-line treatment AFP≥ 400 ng/ml was significantly higher than placebo 。 Among them, the median OS of patients in the remoxilizumab group was 8.
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2022CSH Prof. Mingfeng Zhao: Research progress of CAR-T cells in the treatment of acute myeloid leukemia
Time of Update: 2022-10-13
The 2018 American Hematology Annual Meeting (ASH) reported efficacy results in a targeted CD123 CAR-T therapy in which 4/6 patients with AML achieved complete remission (CR) after treatment; However, many researchers, including Professor Zhao Mingfeng's team, have not been able to repeat such good results in subsequent trials.
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2022CSH | Professor Wang Jin: CAR-T cell therapy is a double-edged sword, and the prospect of ALL new drug treatment is considerable
Time of Update: 2022-10-13
In recent years, he has published more than 30 academic works as the first or corresponding author in internationally renowned journalsAs the first person in charge, he undertook 8 projects, including major national science and technology cooperation projects, national natural science foundation projects and key projects of Shanghai Municipal Science and Technology Commission, and was selected as a "double hundred people" research physician in the Shanghai Municipal Education Commission's Summit Plateau Program - Jiaoyi Medicine.
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Are you aware of the "hereditary tumor susceptibility syndrome" associated with an increased risk of stomach cancer?
Time of Update: 2022-10-13
According to the literature, germline truncation mutations of the tumor suppressor gene CDH1 (encoding the intercellular adhesion protein E-cadherin) have been found in 30% to 50% of HDGC patients' families.
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When will immunotherapy benefit more? 2022 ESMO Reveals the Answer!
Time of Update: 2022-10-13
*For medical professionals onlyUsed before surgery, the risk of death is reduced by 37%!Adjuvant treatment group of 159 people, direct surgery, postoperative use of 18 doses of K drugs;In the neoadjuvant treatment group, 154 people were first treated with 3 doses of K drugs before surgery, and 15 doses of K drugs were used after surgery.
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Research frontiers Efficacy and safety of radium-223 in patients with mCRPC with asymptomatic bone metastases
Time of Update: 2022-10-13
Study the designEXCAAPE (NCT03002220) is a multicenter, single-armed, open-label, uncontrolled Phase IIa trial of 52 patients with mCRPC with asymptomatic BMS who developed progress after treatment with abiraterone or enzalumine.
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Immunotherapy enables patients with gastroesophageal cancer to achieve a high rate of complete remission
Time of Update: 2022-10-13
Commenting on NEONIPIGA is a landmark study that shows that patients with MSI-H esophageal gastric adenocarcinoma achieve high pathological complete remission rates after receiving neoadjuvant therapy with ipimumab and navurizumab.
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Colonoscopy can help! Colonoscopy is required for these 22 conditions
Time of Update: 2022-10-13
*For medical professionals only"Small symptoms" may indicate "big problems"Colonoscopy is the most important method for early detection of colorectal cancer, it will be colonoscopy through the anus in
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Guidelines Overview China Guidelines for the Diagnosis and Treatment of Mantle Cell Lymphoma (2022 Edition)
Time of Update: 2022-10-13
Since the release of the "Chinese Expert Consensus on the Diagnosis and Treatment of Mantle Cell Lymphoma (2016 Edition)", it has greatly promoted the understanding of the disease among medical workers in China and standardized clinical diagnosis and treatment.
