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Editor in charge: Food Science
0
Traditional analytical techniques in food safety focus on the determination of the average content of hazardous substances, and it is difficult to obtain information on the spatial distribution of hazardous substances.
The lack of information on the spatial distribution of risk substances will lead to insufficient scientific setting of the limit standards.
Therefore, it is crucial to study the spatial distribution of hazardous substances.
Important
.
Recently, Zhang Feng, chief expert team of the Chinese Academy of Inspection and Quarantine Sciences, has made breakthroughs in the research on the spatial distribution of risky substances in food.
At present, the imaging technologies widely used in the study of the spatial distribution of food safety risk substances mainly include hyperspectral imaging, terahertz imaging, Raman spectroscopy imaging, etc.
, which have the advantages of simple operation, non-destructive, and no pre-processing.
However, there are still the following technical bottlenecks: ( 1) The spatial resolution is low and it is difficult to analyze complex systems; (2) It is easy to be interfered by environmental factors and difficult to achieve accurate analysis; (3) The detection sensitivity is low and it is difficult to analyze trace substances
.
As a new type of molecular imaging technology, mass spectrometry imaging can obtain in-situ visualized spatial distribution information of substances in tissue slices.
In this report, the research team first optimized the spray substrate, slice thickness, laser dots and other key parameters, established a mass spectrometry imaging analysis method for PFOA in zebrafish model organisms, and used it to monitor the PFOA of different zebrafish tissues exposed to a simulated PFOA environment.
Dynamic distribution
.
By analyzing the changing laws of MSI data with high spatial resolution, an exponential function model suitable for type I tissues (heart, gallbladder, liver, kidney, intestine) and type II tissues (brain, fish bladder, spine, gills, etc.
The research was completed by Bian Yu, a graduate student of the Chinese Academy of Inspection and Quarantine Science, under the guidance of Zhang Feng's chief expert, and was assisted by researcher Ling Yun, Dr.
He Muyi and other teachers.
The research paper was published in the SCI Zone 1 TOP journal Environmental pollution (IF = 8.
071 ) On
.
This work was supported by the national key research and development program
Researcher Zhang Feng
Zhang Feng, Ph.
D.
, researcher, national special support talent for high-level talents, young and middle-aged innovation leader in the "Innovative Talent Promotion Plan" of the Ministry of Science and Technology
Research direction: detection and detection technology of unknown hazardous substances in food; green food safety detection technology; unknown risk holographic determination technology; development of high-selective ion source mass spectrometry; mass spectrometry imaging technology
.
Scientific research achievements: presided over 1 second prize of National Science and Technology Progress Award, 3 first prizes of Science and Technology Award of China Analysis and Testing Association, and 1 first prize of "Science and Technology Inspection Award" from the former General Administration of Quality Supervision, Inspection and Quarantine
.
In Analytical Chemistry , Journal of Agricultural and Food Chemistry published magazine articles and more than 200 domestic and foreign, of which the first or corresponding author published 69 SCI papers, edited 6 books, 14 patents, the development of national standards 9
