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Original: Zero sugar is also unhealthy? The Cell paper confirmed that artificial sweeteners affect the gut microbiota and alter blood sugar
With economic development and rising living standards, obesity has become a major public health problem
Up to 2.
Human sweetener
However, do these artificial sweeteners have an effect on the human body? Are they really healthy?
On August 19, 2022, researchers at the Weizmann Institute of Science published a research paper
Cell
The study confirmed that artificial sweeteners (sugar substitutes) that have long been considered healthy and widely used are not inert in the human body, and that they can significantly affect the human gut microbiome, thereby altering the body's blood sugar levels
Artificial sweeteners that have long been considered healthy and widely used are not inert in the human body, they can significantly affect the human gut microbiome, thereby altering the body's blood sugar levels
Back in 2014, eran Elinav's team at the Weizmann Institute of Science found that non-nutritive artificial sweeteners affected the gut microbiome of mice, affecting their blood glucose response
Eran Elinav
To address this important question, the research team carefully screened more than 1,300 people who strictly avoided the use of artificial sweeteners in their daily lives and identified 120 people from them to participate in follow-up experiments
Saccharin sucralose steviol glycoside aspartame
Eran Elinav, co-corresponding author of the paper, said that in participants who consumed artificial sweeteners, it was easy to observe very pronounced changes
Eran Elinav saccharin and sucralose can more significantly affect glucose tolerance in healthy adults
To determine the causal relationship between these changes, the research team transplanted the gut microbiomes of these human participants into germ-free mice that had previously been reared in a completely sterile environment and had no microbiome
The results were so surprising that after the gut microbiomes of all participants who consumed artificial sweeteners were transplanted to germ-free mice, the mice showed very similar blood glucose changes
The research team said that the effects of these artificial sweeteners on humans may vary from person to person, after all, each person's gut microbiome is highly heterogeneous
Eran Elinav said: "Additional sugar is very harmful to human metabolism, and while we avoid eating sugar, we need to continue to find ways
Eran Elinav drinking only water seems to be the best solution
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