World Alzheimer's Day | How to prevent incurable diseases?

Dementia, also known as cognitive disorders, cognitive disorders, dementia, including Alzheimer's that is common in Alzheimer's disease, which is a high morbidity, high mortality of neurodegenerative diseases, with The patient’s condition develops, with amnesia, dementia, and disability, accompanied by abnormal mental behavior.
The condition may last for 8-20 years.
The cause of the disease is complicated and there is currently no cure.
However, the development of the condition can be delayed and improved by means of drugs, rehabilitation, etc.
The patient’s quality of life
.

Dementia, also known as dementia, dementia, and dementia, includes the common Alzheimer’s disease, Alzheimer’s disease, which is a neurodegenerative disease with high disability and mortality.
Development, patients with amnesia, dementia, disability, and abnormal mental behavior, the condition may last 8-20 years, the cause of the disease is complicated, and there is no cure at present, but it can delay the development of the condition and improve the patient through drugs, rehabilitation, etc.
Quality of life
.

 

 

According to statistics, there are approximately 10 million Alzheimer's disease patients in China
.

With the accelerated aging of the social population, it is estimated that by 2050, the number of patients in China will reach 40 million, which will cause a serious burden on patients' families and society

According to statistics, there are approximately 10 million Alzheimer's disease patients in China

 

 

AD is a degenerative disease of the central nervous system.
The clinical manifestations are cognitive impairment and mental behavior disorder.
The course of the disease is chronic and progressive.
It is the most common type of senile dementia
.

At present, all therapeutic drugs for AD are mainly aimed at delaying the progression of the disease as much as possible, and no drug has been proven to be truly effective in treating AD

AD is a degenerative disease of the central nervous system.

 

The so-called PCAD, as the name suggests, refers to patients with early AD pathological changes, but have not yet reached the earlier stage of clinical mild cognitive impairment (MCI) and dementia diagnostic criteria
.

This period of time may be as long as 15-20 years, during which the patient may have no symptoms

The so-called PCAD, as the name suggests, refers to patients with early AD pathological changes, but have not yet reached the earlier stage of clinical mild cognitive impairment (MCI) and dementia diagnostic criteria

 

 

 

Although the complex etiology of AD is not yet fully understood, it is generally believed that the accumulation of beta amyloid (Aβ42) in the brain into plaques and the production of neurofibrillary tangles Tau protein are responsible for the damage, death, and induction of brain neurons.
Two major factors of AD
.

Therefore, it is pointed out that primary prevention and secondary prevention measures should be actively taken in the PCAD stage .

Although the complex etiology of AD is not yet fully understood, it is generally believed that the accumulation of beta amyloid (Aβ42) in the brain into plaques and the production of neurofibrillary tangles Tau protein are responsible for the damage, death, and induction of brain neurons.

 

10 early warning signs of dementia:

10 early warning signs of dementia : 10 early warning signs of dementia:

 

  

  1.
memory loss

  1.
Memory loss   1.
Memory loss

 

  

  2.
Do not do familiar work

  2.
Can't do familiar work   .
2.
Can't do familiar work.

 

  

  3.
Difficulty in language communication

  3.
Language communication difficulties   3.
Language communication difficulties

 

  

  4.
Can't figure out the time and place

  4.
Can't figure out the time and place   4.
Can't figure out the time and place

 

  

  5.
Decreased thinking and judgment

  5.
Decreased   thinking and judgment 5.
Decreased thinking and judgment

 

  

  6.
Can't figure out the context

  6.
Can't figure out the context of   events 6.
Can't figure out the context of events

 

  

  7.
Misplaced things

  7.
Things are misplaced   7.
Things are misplaced

 

  

  8.
Changes in personality and behavior

  8.
Change in   character behavior 8.
Change in character behavior

 

  

  9.
Difficulty in understanding visual and auditory information

  9.
Difficulty in   understanding visual and auditory information 9.
Difficulty in understanding visual and auditory information

 

  

  10.
Withdraw from work or social activities

  10.
Withdraw from work or social activities   10.
Withdraw from work or social activities

 

  Once the early symptoms appear, family members should promptly accompany the elderly to the geriatrics, neurology, memory clinic or mental health specialist hospital of the general hospital
.

 With the deepening of research on AD, people's awareness of the disease has gradually improved, and they have gradually gained better experience and technology in the prevention and treatment of the disease .

IMR blood protein ultra trace detection technology allows early diagnosis of AD is more convenient, accurate and ultra trace its sensitivity and precision degree, can occur in AD 15-20 years before clinical symptoms detected Aβ42 and abnormal Tau protein content start Increase, and then as a means of medical intervention

Prevention of Alzheimer's disease : Prevention of Alzheimer's disease: ♦Reduce the intake of sugar, salt, and oil: usually have a light diet and try to eat less food containing sugar, salt, and oil .
♦Reduce the intake of sugar, salt, and oil: usually eat lightly, and try to eat less food containing sugar, salt, and oil .
♦Drink less or don't drink strong alcohol: Alcohol can not only reduce the density of brain cells, but also cause brain cells to shrink quickly .
♦Drink less or don't drink strong alcohol: Alcohol can not only reduce the density of brain cells, but also cause brain cells to shrink quickly .
♦ Think much ground brains: often some mental activities, such as reading, playing chess and so on .
♦ Think much ground brains: often some mental activities, such as reading, playing chess and so on .
Don't smoke: Smoking can cause insufficient blood supply to the brain and atrophy of brain cells, so you should actively quit smoking .
Don't smoke: Smoking can cause insufficient blood supply to the brain and atrophy of brain cells, so you should actively quit smoking .
♦ Active physical activity: Proper physical activity will speed up people's blood circulation, so that brain cells will get sufficient nutrients and oxygen .
Therefore, regular participation in sports activities can prevent Alzheimer's disease .
♦ Active physical activity: Proper physical activity will speed up people's blood circulation, so that brain cells will get sufficient nutrients and oxygen .
Therefore, regular participation in sports activities can prevent Alzheimer's disease .
           

 

Patients with Alzheimer's disease should be actively treated.
Drug therapy and non-drug therapy can help patients improve cognitive function, reduce complications, improve quality of life, and reduce burden .
Under the guidance of professionals, non-drug treatments such as sensory stimulation, physical and intelligent exercises, and environmental therapy can be carried out .
For the patients' families and all walks of life in society, making changes from the depths of their hearts, attitudes, and actions can bring warmth and courage to face AD ​​patients .
knowledge is power! World Alzheimer’s Day 2021 focuses on the popularization of knowledge, early screening and early diagnosis .
Once we have the knowledge of Alzheimer's disease prevention and treatment through popular science and education, and once we understand our own memory changes through screening, we will be armed with knowledge, respect, kindness and help, and we can be more effective and more effective.
Comprehensively prepare for, respond to, overcome and defeat the intrusion of Alzheimer's disease on yourself and your family .
References 1.
Lai Siqiang, Li Peng, Ma Tianjun, et al.
Research progress in Alzheimer's disease in the preclinical stage[J].
Chinese Journal of Nervous and Mental Diseases, 2016(12): 760-763.
2.
Elliott, C.
, Masliah ,E.
, Ryan, L.
, & Silverberg, N.
(2018).
Nia-aa research framework: toward a biological definition of alzheimer'sdisease.
Alzheimers & Dementia the Journal of the Alzheimers Association,14(4), 535.
   3.
5-2.
Youn,YC,Kang,S.
,Suh,J.
,Park,YH,Kang,MJ,&Pyun,JM,etal.
(2019).
Blood amyloid-β oligomerization associated with neurodegeneration of alzheimer's disease.
Alzheimer's research & therapy, 11(1), 40.
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